Evolution of the T1 retroposon family in the Anopheles gambiae complex.

abstract：:Cysteine-rich secretory proteins (CRISPs) are glycoproteins found exclusively in vertebrates and have broad diversified functions. They are hypothesized to play important roles in mammalian reproduction and in reptilian venom, where they disrupt homeostasis of the prey through several mechanisms, including among other...

journal_title：Molecular biology and evolution

authors： Sunagar K,Johnson WE,O'Brien SJ,Vasconcelos V,Antunes A

更新日期：2012-07-01 00:00:00

abstract：:Various hypotheses for the peopling of the Japanese archipelago have been proposed, which can be classified into three models: transformation, replacement, and hybridization. In recent years, one of the hybridization models ("dual-structure model") has been widely accepted. According to this model, Neolithic hunter-ga...

journal_title：Molecular biology and evolution

authors： Nakagome S,Sato T,Ishida H,Hanihara T,Yamaguchi T,Kimura R,Mano S,Oota H,Asian DNA Repository Consortium.

更新日期：2015-06-01 00:00:00

abstract：:Thyroid hormones are involved in the regulation of growth and metabolism in all vertebrates. Transthyretin is one of the extracellular proteins with high affinity for thyroid hormones which determine the partitioning of these hormones between extracellular compartments and intracellular lipids. During vertebrate evolu...

journal_title：Molecular biology and evolution

authors： Prapunpoj P,Richardson SJ,Fumagalli L,Schreiber G

更新日期：2000-08-01 00:00:00

abstract：:Previous studies have shown that genes that are expressed predominantly or exclusively in males tend to evolve rapidly in comparison to other genes. In most cases, however, it is unknown whether this rapid evolution is the result of increased positive (or sexual) selection on male-expressed traits or if it is due to a...

journal_title：Molecular biology and evolution

authors： Zhang Z,Parsch J

更新日期：2005-10-01 00:00:00

abstract：:Functional redundancy in genomes arises from genes with overlapping functions, allowing phenotypes to persist after gene knockouts. Evolutionary redundancy or evolvability of a genome is one step removed, in that functional redundancy is absent but the genome has the potential to evolve to restore a lost phenotype. Ex...

journal_title：Molecular biology and evolution

authors： Heineman RH,Bull JJ,Molineux IJ

更新日期：2009-06-01 00:00:00

abstract：:The guppy sex chromosomes show an extraordinary diversity in divergence across populations and closely related species. In order to understand the dynamics of the guppy Y chromosome, we used linked-read sequencing to assess Y chromosome evolution and diversity across upstream and downstream population pairs that vary ...

journal_title：Molecular biology and evolution

authors： Almeida P,Sandkam BA,Morris J,Darolti I,Breden F,Mank JE

更新日期：2021-01-23 00:00:00

abstract：:We report the presence of four nuclear paralogs of a 380-bp segment of cytochrome b in callitrichine primates (marmosets and tamarins). The mitochondrial cytochrome b sequence and each nuclear paralog were obtained from several species, allowing multiple comparisons of rates and patterns of substitution both between m...

journal_title：Molecular biology and evolution

authors： Mundy NI,Pissinatti A,Woodruff DS

更新日期：2000-07-01 00:00:00

abstract：:Employing comparative analysis of the cDNA-coding sequences of the unique preprorelaxin of the Afro-lorisiform Galago crassicaudatus and the Malagasy lemur Varecia variegata and the relaxin-like factor (RLF) of G. crassicaudatus, we demonstrated distinct differences in the dynamics of molecular remodeling of both horm...

journal_title：Molecular biology and evolution

authors： Klonisch T,Froehlich C,Tetens F,Fischer B,Hombach-Klonisch S

更新日期：2001-03-01 00:00:00

abstract：:Past analyses of the genome of the yeast Saccharomyces cerevisiae have revealed substantial regional variation in G+C content. Important questions remain, though, as to the origin, nature, significance, and generality of this variation. We conducted an extensive analysis of the yeast genome to try to answer these ques...

journal_title：Molecular biology and evolution

authors： Bradnam KR,Seoighe C,Sharp PM,Wolfe KH

更新日期：1999-05-01 00:00:00

abstract：:The ability to counter periods of low humidity is an important determinant of distribution range in Drosophila. Climate specialists with low physiological tolerance to desiccation stress are restricted to the tropics and may lack the ability to further increase resistance through evolution. Although the physiological ...

journal_title：Molecular biology and evolution

authors： Telonis-Scott M,Gane M,DeGaris S,Sgrò CM,Hoffmann AA

更新日期：2012-05-01 00:00:00

abstract：:Ecological diversity in fungi is largely defined by metabolic traits, including the ability to produce secondary or "specialized" metabolites (SMs) that mediate interactions with other organisms. Fungal SM pathways are frequently encoded in biosynthetic gene clusters (BGCs), which facilitate the identification and cha...

journal_title：Molecular biology and evolution

authors： Gluck-Thaler E,Haridas S,Binder M,Grigoriev IV,Crous PW,Spatafora JW,Bushley K,Slot JC

更新日期：2020-10-01 00:00:00

abstract：:The plant pathogen Phytophthora infestans emerged in Europe in 1845, triggering the Irish potato famine and massive European potato crop losses that continued until effective fungicides were widely employed in the 20th century. Today the pathogen is ubiquitous, with more aggressive and virulent strains surfacing in re...

journal_title：Molecular biology and evolution

authors： Martin MD,Ho SY,Wales N,Ristaino JB,Gilbert MT

更新日期：2014-06-01 00:00:00

abstract：:Heme biosynthesis represents one of the most essential metabolic pathways in living organisms, providing the precursors for cytochrome prosthetic groups, photosynthetic pigments, and vitamin B(12). Using genomic data, we have compared the heme pathway in the diatom Thalassiosira pseudonana and the red alga Cyanidiosch...

journal_title：Molecular biology and evolution

authors： Oborník M,Green BR

更新日期：2005-12-01 00:00:00

abstract：:Coevolutionary conflict among imprinted genes that influence traits such as offspring growth may arise when maternal and paternal genomes have different evolutionary optima. This conflict is expected in outcrossing taxa with multiple paternity, but not self-fertilizing taxa. MEDEA (MEA) is an imprinted plant gene that...

journal_title：Molecular biology and evolution

authors： Miyake T,Takebayashi N,Wolf DE

更新日期：2009-04-01 00:00:00

abstract：:The genotypic signature of spatially varying selection is ubiquitous across the Drosophila melanogaster genome. Spatially structured adaptive phenotypic differences are also commonly found, particularly along New World and Australian latitudinal gradients. However, investigation of gene expression variation in one or ...

journal_title：Molecular biology and evolution

authors： Levine MT,Eckert ML,Begun DJ

更新日期：2011-01-01 00:00:00

abstract：:It is widely accepted that evolutionary changes in conserved developmental signaling pathways play an important role in morphological evolution. However, few in silico studies were interested in tracking such changes in a signaling pathway. The Ectodysplasin (EDA) pathway provides an opportunity to fill this gap becau...

journal_title：Molecular biology and evolution

authors： Pantalacci S,Chaumot A,Benoît G,Sadier A,Delsuc F,Douzery EJ,Laudet V

更新日期：2008-05-01 00:00:00

abstract：:The spread of farming out of the Balkans and into the rest of Europe followed two distinct routes: An initial expansion represented by the Impressa and Cardial traditions, which followed the Northern Mediterranean coastline; and another expansion represented by the LBK (Linearbandkeramik) tradition, which followed the...

journal_title：Molecular biology and evolution

authors： Olalde I,Schroeder H,Sandoval-Velasco M,Vinner L,Lobón I,Ramirez O,Civit S,García Borja P,Salazar-García DC,Talamo S,María Fullola J,Xavier Oms F,Pedro M,Martínez P,Sanz M,Daura J,Zilhão J,Marquès-Bonet T,Gilbert MT,

更新日期：2015-12-01 00:00:00

abstract：:Convergent and parallel amino acid substitutions in protein evolution, collectively referred to as molecular convergence here, have small probabilities under neutral evolution. For this reason, molecular convergence is commonly viewed as evidence for similar adaptations of different species. The surge in the number of...

journal_title：Molecular biology and evolution

authors： Zou Z,Zhang J

更新日期：2015-08-01 00:00:00

abstract：:Human histatins are a family of low-M(r), neutral to very basic, histidine-rich salivary polypeptides. They probably function as part of the nonimmune host defense system in the oral cavity. A 39-kb region of DNA containing the HIS1 and HIS2 genes was isolated from two human genomic phage libraries as a series of over...

journal_title：Molecular biology and evolution

authors： Sabatini LM,Ota T,Azen EA

更新日期：1993-05-01 00:00:00

abstract：:The chemokine receptor CCR5 can serve as a coreceptor for M-tropic HIV-1 infection and both M-tropic and T-tropic SIV infection. We sequenced the entire CCR5 gene from 10 nonhuman primates: Pongo pygmaeus, Hylobates leucogenys, Trachypithecus francoisi, Trachypithecus phayrei, Pygathrix nemaeus, Rhinopithecus roxellan...

journal_title：Molecular biology and evolution

authors： Zhang YW,Ryder OA,Zhang YP

更新日期：1999-09-01 00:00:00

abstract：:Two recent studies have presented conflicting views on variation present within the 294 base third domain of the 12S rRNA gene in the genus Drosophila, and in D. pseudoobscura in particular. One study suggested that this gene is highly invariant across the genus, while another recovered 22 distinct haplotypes from 22 ...

journal_title：Molecular biology and evolution

authors： Noor MA,Larkin JC

更新日期：2000-06-01 00:00:00

abstract：:Whether coding or regulatory sequence change is more important to the evolution of phenotypic novelty is one of biology's major unresolved questions. The field of evo-devo has shown that in early development changes to regulatory regions are the dominant mode of genetic change, but whether this extends to the evolutio...

journal_title：Molecular biology and evolution

authors： Jasper WC,Linksvayer TA,Atallah J,Friedman D,Chiu JC,Johnson BR

更新日期：2015-02-01 00:00:00

abstract：:Over time, natural selection molds every gene into a unique mosaic of sites evolving rapidly or resisting change-an "evolutionary fingerprint" of the gene. Aspects of this evolutionary fingerprint, such as the site-specific ratio of nonsynonymous to synonymous substitution rates (dN/dS), are commonly used to identify ...

journal_title：Molecular biology and evolution

authors： Pond SL,Scheffler K,Gravenor MB,Poon AF,Frost SD

更新日期：2010-03-01 00:00:00

abstract：:Current phylogenetic tree reconstruction methods assume that there is a single underlying tree topology for all sites along the sequence. The presence of mosaic sequences due to recombination violates this assumption and will cause phylogenetic methods to give misleading results due to the imposition of a single tree ...

journal_title：Molecular biology and evolution

authors： McGuire G,Wright F,Prentice MJ

更新日期：1997-11-01 00:00:00

abstract：:Numerous studies have used indices of genetic distance between species to reconstruct evolutionary relationships and to estimate divergence time. However, the empirical relationship between molecular-based indices of genetic divergence and divergence time based on the fossil record is poorly known. To date, the result...

journal_title：Molecular biology and evolution

authors： Wayne RK,Van Valkenburgh B,O'Brien SJ

更新日期：1991-05-01 00:00:00

abstract：:Parasites sometimes expand their host range by acquiring a new host species. After a host change event, the selective regime acting on a given parasite gene may change as a result of host-specific adaptive alterations of protein functionality or host-specific immune-mediated selection. We present a codon-based model t...

journal_title：Molecular biology and evolution

authors： Forsberg R,Christiansen FB

更新日期：2003-08-01 00:00:00

abstract：:Accurately inferring the genome-wide landscape of recombination rates in natural populations is a central aim in genomics, as patterns of linkage influence everything from genetic mapping to understanding evolutionary history. Here, we describe recombination landscape estimation using recurrent neural networks (ReLERN...

journal_title：Molecular biology and evolution

authors： Adrion JR,Galloway JG,Kern AD

更新日期：2020-06-01 00:00:00

abstract：:Heuristic approaches were used to quantify the influence that sequencing errors have on estimates of nucleotide diversity, substitution rate, and the construction of genealogies. Error rates of less than 1 nucleotide/kb probably have little affect on conclusions about the evolutionary history of highly polymorphic org...

journal_title：Molecular biology and evolution

authors： Clark AG,Whittam TS

更新日期：1992-07-01 00:00:00

abstract：:The malaria parasite's chloroquine resistance transporter (CRT) is an integral membrane protein localized to the parasite's acidic digestive vacuole. The function of CRT is not known and the protein was originally described as a transporter simply because it possesses 10 transmembrane domains. In wild-type (chloroquin...

journal_title：Molecular biology and evolution

authors： Martin RE,Kirk K

更新日期：2004-10-01 00:00:00

abstract：:In correctly predicting that selection efficiency is positively correlated with the effective population size (Ne), the nearly neutral theory provides a coherent understanding of between-species variation in numerous genomic parameters, including heritable error (germline mutation) rates. Does the same theory also exp...

journal_title：Molecular biology and evolution

authors： Ho AT,Hurst LD

更新日期：2021-01-04 00:00:00