Postoperative pancreatic fistula after distal pancreatectomy for non-pancreas retroperitoneal tumor resection.

Abstract:

INTRODUCTION:Short-term outcomes after distal pancreatectomy (DP) for retroperitoneal (RP) tumors are unknown. We sought to identify rates of postoperative pancreatic fistula (POPF) and morbidity after en bloc DP with RP tumor resection. METHODS:A retrospective review of 43 patients who underwent DP with RP tumor resection (1/2011-12/2017) was performed. RESULTS:Seventeen patients had RP sarcoma, 12 renal cell carcinoma, 11 gastrointestinal stromal tumor, and 3 adrenocortical carcinoma. Grade III-IV complications occurred in 7 patients. Grade B POPF occurred in 14 patients, grade C POPF in none, and biochemical leak in 6. Of 22 patients who developed radiographically evident peri-pancreatic fluid collections, 7 required percutaneous drainage. The 90-day readmission rate was 33%. CONCLUSIONS:DP with RP tumor resection is associated with high rates of clinically relevant POPF compared to historical results for DP for primary pancreatic tumors. Multi-center studies to identify targetable predictors and risk mitigation strategies for POPF in this rare high-risk population are needed.

journal_name

Am J Surg

authors

Keung EZ,Asare EA,Chiang YJ,Prakash LR,Rajkot N,Torres KE,Hunt KK,Feig BW,Cormier JN,Roland CL,Katz MHG,Lee JE,Tzeng CD

doi

10.1016/j.amjsurg.2019.11.026

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

140-146

issue

1

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(19)31540-5

journal_volume

220

pub_type

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