Abstract:
:Titanium osteosynthesis is currently the fixation system of choice in maxillofacial traumatology. Biodegradable osteosynthesis systems have the ability to degrade in the human body. The aim of this study was to conduct a systematic review, with meta- and trial sequential analyses, to assess the efficacy and morbidity of biodegradable versus titanium osteosynthesis after maxillofacial trauma. MEDLINE, Embase, and CENTRAL were searched for randomized controlled trials and prospective and retrospective controlled studies. Five time periods were studied: perioperative, short-term (0-4 weeks), intermediate (6-12 weeks), long-term (>12 weeks), and overall follow-up. After screening 3542 records, 24 were included. All had a high risk of performance and detection bias due to the nature of the interventions. Meta-analysis showed no differences in efficacy or morbidity between biodegradable and titanium osteosynthesis. The risk of perioperative screw breakage was significantly higher (risk ratio 17.13, 95% confidence interval 2.19-34.18) and the symptomatic plate removal rate lower in the biodegradable group (risk ratio 0.11, 95% confidence interval 0.02-0.57), which was confirmed by the trial sequential analysis. The quality of evidence ranged from very low to moderate. Based on the narrative review and meta-analyses, current evidence shows that biodegradable osteosynthesis is a viable alternative to titanium osteosynthesis when applied in the treatment of maxillofacial trauma, with similar efficacy but significantly lower symptomatic plate removal rates. Perioperative screw breakage occurred significantly more often in the biodegradable group compared to the titanium group.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Gareb B,van Bakelen NB,Dijkstra PU,Vissink A,Bos RRM,van Minnen Bdoi
10.1016/j.ijom.2019.11.009subject
Has Abstractpub_date
2020-07-01 00:00:00pages
914-931issue
7eissn
0901-5027issn
1399-0020pii
S0901-5027(19)31407-9journal_volume
49pub_type
杂志文章,meta分析abstract::Two examples are presented of osteotomies performed simultaneously with surgical recontouring in cases of fibrous dysplasia of the jaws. Osteotomies are necessary when a coexistent discrepancy in jaw relationship is present. This provides a functional as well as aesthetic result. Rigid miniplate fixation was utilised,...
journal_title:International journal of oral and maxillofacial surgery
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abstract::Pre- and postoperative longitudinal assessment of oral functions including masticatory force, masticatory ability with solids, speech intelligibility, and subjective satisfaction was conducted for patients who underwent vascularized osteocutaneous scapula flap reconstruction after mandibulectomy. Postoperative changes...
journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,多中心研究,随机对照试验
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abstract::Parotid lymph node (PLN) metastasis greatly worsens the prognosis of patients with oral squamous cell carcinoma (OSCC) and poses a great challenge for further treatment of OSCC. The clinicopathological characteristics and treatment strategies for PLN metastasis from OSCC need to be comprehensively elucidated. A retros...
journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2005.02.015
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journal_title:International journal of oral and maxillofacial surgery
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doi:10.1016/j.ijom.2017.04.029
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abstract::A case of metastatic osteosarcoma in the submental vestibule of the oral cavity and the lung is described in an 18-year-old male with primary osteosarcoma occurring in the sacrum. Dissemination of osteosarcoma to other organs, especially early to the lung, is common, but its metastasis to the oral mucosa has been rare...
journal_title:International journal of oral and maxillofacial surgery
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doi:10.1016/j.ijom.2006.04.004
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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doi:10.1016/j.ijom.2006.02.011
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2020.06.015
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/s0901-5027(05)80085-2
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journal_title:International journal of oral and maxillofacial surgery
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doi:10.1016/j.ijom.2005.04.010
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pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章
doi:10.1016/j.ijom.2006.08.014
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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