Abstract:
:Central giant cell granuloma (CGCG) is a benign lesion of the jaws with a sometimes locally aggressive behaviour. The most common therapy is surgical curettage which has a high recurrence rate, especially in lesions with aggressive signs and symptoms (i.e. pain, paresthesia, root-resorption and rapid growth). Alternative therapies such as interferon alpha (INFalpha) or calcitonin are described in the literature. In this study 2 patients with an aggressive CGCG are presented who were treated with INF mono-therapy. INF mono-therapy was capable of terminating the rapid growth of the lesion in both patients and induced a partial reduction. Total resolution, however, was not obtained and alternative treatment is still necessary.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
de Lange J,van den Akker HP,van den Berg H,Richel DJ,Gortzak RAdoi
10.1016/j.ijom.2006.02.011subject
Has Abstractpub_date
2006-09-01 00:00:00pages
865-9issue
9eissn
0901-5027issn
1399-0020pii
S0901-5027(06)00109-3journal_volume
35pub_type
杂志文章abstract::This study assessed the impact of oral and maxillofacial trauma and surgical treatment on the quality of life of patients. The study included 66 patients (age range 18-65 years) with facial fractures; 33 required surgical treatment and 33 required conservative (non-surgical) treatment. Quality of life was evaluated by...
journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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abstract::A 7-year-old boy presented in whom a metaphyseal fibrous defect was diagnosed. The lesion was enucleated under local anesthesia. The postoperative course was uneventful and there have been no signs of recurrence as of 14 months after operation. Although rare, metaphyseal fibrous defect should be included in the differ...
journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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doi:10.1016/j.ijom.2009.01.015
更新日期:2009-06-01 00:00:00
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更新日期:1994-12-01 00:00:00
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更新日期:2017-10-01 00:00:00
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journal_title:International journal of oral and maxillofacial surgery
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pub_type: 临床试验,杂志文章
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,meta分析,评审
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