Abstract：
:Central giant cell granuloma (CGCG) is a benign lesion with unpredictable biological behaviour ranging from a slow-growing asymptomatic swelling to an aggressive lesion associated with pain, bone and root resorption and also tooth displacement. The aetiology of the disease is unclear with controversies in the literature on whether it is mainly of reactional, inflammatory, infectious, neoplasic or genetic origin. To test the hypothesis that mutations in the SH3BP2 gene, as the principal cause of cherubism, are also responsible for, or at least associated with, giant cell lesions, 30 patients with CGCG were recruited for this study and subjected to analysis of germ line and/or somatic alterations. In the blood samples of nine patients, one codon alteration in exon 4 was found, but this alteration did not lead to changes at the amino acid level. In conclusion, if a primary genetic defect is the cause for CGCG it is either located in SH3BP2 gene exons not yet related to cherubism or in a different gene.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Teixeira RC,Horz HP,Damante JH,Garlet GP,Santos CF,Nogueira RL,Cavalcante RB,Conrads Gdoi
10.1016/j.ijom.2011.04.003subject
Has Abstractpub_date
2011-08-01 00:00:00pages
851-5issue
8eissn
0901-5027issn
1399-0020pii
S0901-5027(11)00161-5journal_volume
40pub_type
杂志文章abstract：:A systematic review of the literature concerning upper airway imaging and analysis using cone-beam computed tomography (CBCT) was performed. A PubMed search (National Library of Medicine, NCBI; revised 9th January 2011) yielded 382 papers published between 1968 and 2010. The 382 full papers were screened in detail. 46...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2011.06.017
更新日期：2011-11-01 00:00:00
abstract：:Obstructive sleep apnoea (OSA) is a serious condition that can be the cause of a number of systemic symptoms and conditions. The diagnosis of OSA is made by clinical and radiological examination, with polysomnography as the gold standard for recording the severity of the disorder. Among the many therapies offered for ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.01.019
更新日期：2015-06-01 00:00:00
abstract：:This randomized clinical trial was designed to compare three different reduction methods for anterior temporomandibular joint (TMJ) dislocation. The three methods evaluated were the conventional method, wrist pivot method, and extraoral method. The study sample comprised 90 consecutive patients suffering from anterior...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijom.2016.04.015
更新日期：2016-08-01 00:00:00
abstract：:Zygomatic implants (ZIs) are used for the oral rehabilitation of patients with maxillectomy defects as an alternative to extensive bone grafting surgeries. New technologies such as computer-assisted navigation systems can improve the accuracy and safety of ZI placement. The intraoral anchorage of fiducial markers nece...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2020.03.018
更新日期：2021-01-01 00:00:00
abstract：:The aim of this study was to evaluate factors affecting the selection of pectoralis major flap in the era of free tissue reconstruction for post ablative head and neck defects and flap associated complications. The records of patients who underwent various reconstructive procedures between July 2009 and December 2010 ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2011.12.029
更新日期：2012-04-01 00:00:00
abstract：:The concept of a flow-through flap refers to a free flap in which both the proximal and distal ends of the vascular pedicle are anastomosed to provide blood flow to the distal tissues. The purpose of this paper is to highlight the use of this technique, which may be useful in selected cases of head and neck reconstruc...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2020.07.015
更新日期：2020-08-01 00:00:00
abstract：:The results of endoscope-assisted parotid surgery are presented as a minimally invasive alternative to parotidectomy for large parotid stones. From 1999 to 2007, 70 patients with parotid sialoliths were treated by minimally invasive surgical techniques in three specialist centres. At surgery a combination of sialoendo...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.ijom.2009.06.030
更新日期：2010-01-01 00:00:00
abstract：:Histopathology is the gold standard in the diagnosis of cancer and dysplasia. Screening for the disease in high-risk populations(6,15) and choosing the correct site for biopsy have implications for the choice of follow-up intervals and therapy. Sully & Field(12) suggest that molecular genetic analysis, such as the pol...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-01 00:00:00
abstract：:A study was conducted to evaluate 2 prophylactic penicillin regimens in 18 patients undergoing orthognathic surgery. The effects on the oral microflora were also studied. All patients received 3 g benzyl-penicillin as infusion from the beginning of operation and then 3 g every 6th hour during 24 h. One group of 9 pati...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(87)80106-6
更新日期：1987-10-01 00:00:00
abstract：:Open reduction of dislocated subcondylar fractures was carried out in 19 adult patients between 1990 and 1992. A comparison of the results between two groups of patients was made 1 year after trauma. The reference group consisted of patients with the same type of fracture but treated with only intermaxillary fixation ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(96)80052-x
更新日期：1996-04-01 00:00:00
abstract：:The aim of this study was to compare the effect of intramuscular (IM) injection and consumption of 8 mg dexamethasone in patients after lower third molar (LTM) surgery. 20 healthy Thai patients, average age 20 years, with bilateral LTM removal were recruited for this study, a double blinded, paired sample clinical tri...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2011.12.011
更新日期：2012-02-01 00:00:00
abstract：:The general advantages of laser surgery, such as decreased bleeding and dry surgical field, reduced postoperative pain and less oedema, have led to a continuous interest in laser applications for bone cutting. The ability to cut bone with a laser beam would also be of great technical benefit in minimally invasive maxi...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2007.05.019
更新日期：2007-12-01 00:00:00
abstract：:Nitric oxide (NO) has a complex role in tumour biology. Most cancer research has focused on the enzyme nitric oxide synthase-2 (NOS2), an inducible isoform responsible for prolonged NO production. In normal cells exposed to high NO concentrations, the tumour-suppressor gene, p53, promotes apoptosis via the p21 pathway...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1054/ijom.2001.0214
更新日期：2002-04-01 00:00:00
abstract：:This study retrospectively investigates the incidence and risk factors for venous thromboembolism (VTE) in patients undergoing maxillofacial surgery. Data were obtained from patients treated between January 2005 and June 2006. Patients' records were reviewed for complaints and information relating to deep venous throm...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2009.10.024
更新日期：2010-03-01 00:00:00
abstract：:This systematic review aimed to investigate whether intra-articular injections of platelet-rich plasma (PRP) are beneficial for the treatment of degenerative temporomandibular disorders, such as temporomandibular joint osteoarthritis (TMJ-OA) and disc displacement with osteoarthritic lesions, when compared to other tr...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2017.09.014
更新日期：2018-02-01 00:00:00
abstract：:The purpose of this study was to evaluate a personalized orthognathic surgical guide (POSG) system for bimaxillary surgery without the use of surgical splint. Ten patients with dentofacial deformities were enrolled. Surgeries were planned with the computer-aided surgical simulation method. The POSG system was designed...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2017.03.025
更新日期：2017-10-01 00:00:00
abstract：:Cocaine is a very potent vasoconstrictor that is used by ENT specialists to reduce blood loss and enhance visibility during nasal surgery. In orthognathic surgery, especially Le Fort I procedures, excessive blood loss is a relatively frequent complication. In this study, a prospective randomized clinical trial on the ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijom.2007.07.017
更新日期：2008-01-01 00:00:00
abstract：:An unusual presentation of non-Hodgkins lymphoma is presented in an immunocompromised patient. The importance of having a high index of suspicion for malignancy in transplant patients is stressed. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80708-8
更新日期：1991-04-01 00:00:00
abstract：:Routine use of a palatal injection for the removal of maxillary third molars has never been validated. The purpose of this blinded, randomized, controlled trial was to assess the requirement of a separate palatal injection for the extraction of maxillary third molars. Fifty-one patients requiring the removal of bilate...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijom.2007.06.001
更新日期：2007-12-01 00:00:00
abstract：:The purpose of this prospective study was to evaluate survival and marginal bone loss at 10-year follow-up of implants inserted in completely edentulous arches and immediately loaded using multiple mucosa-supported stereolithographic surgical templates. The influence on marginal bone loss of the following variables wa...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.12.001
更新日期：2016-04-01 00:00:00
abstract：:A 16-year-old male underwent bilateral sagittal split osteotomy of the mandible to correct a mandibular deficiency. Twenty-one years later, a routine panoramic radiograph revealed a radiolucent lesion on the left side of the mandible. The lesion was biopsied. As the patient did not have symptoms and the lesion was con...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2006.10.017
更新日期：2007-05-01 00:00:00
abstract：:The purpose of this study was to evaluate skeletal and dental stability in patients who had temporomandibular joint (TMJ) reconstruction and mandibular counterclockwise advancement using TMJ Concepts total joint prostheses (TMJ Concepts Inc. Ventura, CA) with maxillary osteotomies being performed at the same operation...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2008.11.024
更新日期：2009-02-01 00:00:00
abstract：:A patient with de Lange syndrome who also had a variant of von Willebrand's disease is reported. The problems with dental surgery, particularly with respect to difficulty of extraction and bleeding tendency, are discussed. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80246-2
更新日期：1993-06-01 00:00:00
abstract：:With the continuing progress in medicine, the number of successful organ transplantations has continued to increase, a fact that also concerns dentists and implantologists. Implantology after organ transplantation remains controversial due to the patient's immunocompromised situation and the corresponding risk of infe...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.11.002
更新日期：2016-05-01 00:00:00
abstract：:Recreating a harmonious gingival contour for contiguous missing teeth in the anterior maxilla is challenging. The aim of this study was to evaluate a split pedicle roll envelope technique designed for pontics. Twelve patients presented a labial flat or concave profile at the implant and pontic sites before second-stag...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2015.04.012
更新日期：2015-10-01 00:00:00
abstract：:A patient is presented with a large pituitary adenoma that was successfully treated with a Le Fort I osteotomy in combination with mandibulotomy. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：:The purpose of this review was to integrate the clinical, radiological, microscopic, and molecular data of published cherubism cases, in addition to therapeutic approaches, to provide more concise information about the disease. An electronic search was undertaken in September 2019. Eligibility criteria included public...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2020.05.021
更新日期：2021-01-01 00:00:00
abstract：:A systematic review of English and non-English articles on the complications of mandibular distraction osteogenesis (MDO) for patients with developmental deformities was performed, in accordance with the PRISMA statement. Search terms expressing distraction osteogenesis were used in 'AND' combination with search terms...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2014.09.007
更新日期：2015-01-01 00:00:00
abstract：:Leiomyosarcomas are malignant tumours of smooth muscle origin. These tumours are very rare in the head and neck region. We report a case of metastatic uterine leiomyosarcoma masquerading as a primary sarcoma of the masseter muscle. We highlight the importance of considering the possibility of an unrecognised primary a...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2005.08.004
更新日期：2006-05-01 00:00:00
abstract：:Circumferential wiring is executed by various awls and needles. A method is presented by which a needle can be easily transformed into an awl. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80050-5
更新日期：1994-12-01 00:00:00
