Correlation of abdominal ultrasound and computed tomography scans with second- or third-look laparotomy in patients with ovarian carcinoma.

abstract：OBJECTIVE:The consequences of defective homologous recombination and other DNA repair pathways are important in disease outcomes of numerous tumor types. The objective of this study was to explore BRCA1, PARP, FANCD2, PTEN, H2AX, and ATM protein expression in endometrial cancer (EC). METHODS:PARP1, γH2AX, ATM, FANCD2,...

journal_title：Gynecologic oncology

authors： Mhawech-Fauceglia P,Wang D,Kim G,Sharifian M,Chen X,Liu Q,Lin YG,Liu S,Pejovic T

更新日期：2014-03-01 00:00:00

abstract：:During the period 1977 to 1985, 12 patients with FIGO stage II and III epithelial ovarian carcinoma failed to achieve a pathologic complete response with chemotherapy and underwent salvage whole-abdominal irradiation (WAXRT). Six of these patients had gross residual disease present at the time of irradiation, and thre...

journal_title：Gynecologic oncology

authors： Linstadt DE,Stern JL,Quivey JM,Leibel SA,Lacey CG

更新日期：1990-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to develop a risk-scoring system for predicting lymph node and distant metastasis in endometrial carcinoma. METHODS:A total of 1166 patients, treated at a single institution between 1-2007 and 12-2013, were included in the study. The association of stage IIIC-IV disease with demograp...

journal_title：Gynecologic oncology

authors： Tuomi T,Pasanen A,Luomaranta A,Leminen A,Bützow R,Loukovaara M

更新日期：2015-04-01 00:00:00

abstract：:Adenocarcinoma originating in the endocervix may remain occult for many years. This may result in an extension to the uterine isthmus and corpus, with subsequent dissemination along the pathways of spread of uterine carcinoma, including metastasis to the ovaries. The patient described in this report had a bulky stage ...

journal_title：Gynecologic oncology

authors： Parham G,Heppard MC,DiSaia PJ

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Uterine leiomyomas rarely cause pseudo-Meigs' syndrome with elevated serum CA 125 levels. CASE:A 39-year-old patient with a large uterine leiomyoma is described. The associated massive ascites, pleural fluid, and increased CA 125 level all seemed to be related to the uterine tumor. Hydropic degenerating lei...

journal_title：Gynecologic oncology

authors： Amant F,Gabriel C,Timmerman D,Vergote I

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the long-term effect of gonadotropin-releasing hormone analogues (GnRH-a) in combination with high-dose progestogens in the treatment of atypical endometrial hyperplasia in selected surgical high-risk patients and in women desiring reproductive potential. We hypothesized th...

journal_title：Gynecologic oncology

authors： Pérez-Medina T,Bajo J,Folgueira G,Haya J,Ortega P

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVES:To compare survival of Hispanic white (HW) and non-Hispanic white (NHW) women with type II endometrial adenocarcinoma (EC). METHODS:Patients with serous, clear cell or grade 3 endometrioid EC were identified from the Surveillance, Epidemiology, and End Results (SEER) program 1988-2009 and were divided into ...

journal_title：Gynecologic oncology

authors： Mahdi H,Hou H,Kowk LL,Moslemi-Kebria M,Michener C

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:To compare the efficacy of chemotherapy (C) combined with bevacizumab (Bev) versus Bev alone in recurrent, heavily pretreated epithelial ovarian cancer (EOC). METHODS:A multicenter analysis of patients treated from 2004 to 2011 was performed. Demographic, treatment, response, and adverse event information w...

journal_title：Gynecologic oncology

authors： Fuh KC,Secord AA,Bevis KS,Huh W,ElNaggar A,Blansit K,Previs R,Tillmanns T,Kapp DS,Chan JK

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:This study was conducted to determine the objective response of trimetrexate in patients with advanced or recurrent leiomyosarcoma of the uterus. METHODS:Eligibility was restricted to patients with measurable disease who had received no more than one prior chemotherapy regimen, who had adequate bone marrow, ...

journal_title：Gynecologic oncology

authors： Smith HO,Blessing JA,Vaccarello L

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:There are currently limited published data available on the safety and feasibility of the prolonged administration of paclitaxel. The goal of this study was to review the cumulative toxicity associated with the continuous long-term administration of this agent to women with gynecologic cancers. METHODS:Eleve...

journal_title：Gynecologic oncology

authors： Rohl J,Kushner D,Markman M

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Development of carcinoma in situ in a neovagina is rare. CASE:A case of carcinoma in situ of a neovagina complicated by recurrence after ablative therapy is discussed. Recurrence occurred within 4 months of initial therapy, and a total vaginectomy was performed after the patient declined other therapeutic o...

journal_title：Gynecologic oncology

authors： Lowe MP,Ault KA,Sood AK

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain. METHODS:1043 histological confirmed ICC cases diagnosed from 1940 to 2007 ...

journal_title：Gynecologic oncology

authors： Alemany L,Pérez C,Tous S,Llombart-Bosch A,Lloveras B,Lerma E,Guarch R,Andújar M,Pelayo A,Alejo M,Ordi J,Klaustermeier J,Velasco J,Guimerà N,Clavero O,Castellsagué X,Quint W,Muñoz N,Bosch FX,de Sanjosé S,Spanish st

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to evaluate a modified MonoPrep2 (MP) of liquid-based cytology (LBC) to search for a less expensive alternative technique usable for screening of cervical cancers. STUDY DESIGN:Cervicovaginal direct-to-vial samples from 1218 consecutive patients were processed with the modified M...

journal_title：Gynecologic oncology

authors： Nam JH,Kim HS,Lee JS,Choi HS,Min KW,Park CS

更新日期：2004-09-01 00:00:00

abstract：:In the field of gynecologic oncology, surgical intervention has been the traditional management of postoperative abdominal hemorrhage. Recently, arterial embolization has been reported to effectively control vaginal hemorrhage associated with gynecologic malignancy, obstetrical trauma, and hysterectomy. This study rep...

journal_title：Gynecologic oncology

authors： O'Hanlan KA,Trambert J,Rodriguez-Rodriguez L,Goldberg GL,Runowicz CD

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:Increased activity of Sp family of transcription factors is a frequent and critical event in cancer development and progression. Genes governing tumor growth, invasion and angiogenesis are regulated by Sp factors, like Sp1, Sp3 or Sp4, and are frequently over-expressed in tumors. Targeting Sp factors has been...

journal_title：Gynecologic oncology

authors： Previdi S,Malek A,Albertini V,Riva C,Capella C,Broggini M,Carbone GM,Rohr J,Catapano CV

更新日期：2010-08-01 00:00:00

abstract：:This article describes the first reported case of a primary transitional cell carcinoma of the renal pelvis metastatic to the ovary. The clinical presentation in our patient was similar to that of a primary ovarian carcinoma. The differential diagnosis of a primary or metastatic transitional cell carcinoma in the ovar...

journal_title：Gynecologic oncology

authors： Hsiu JG,Kemp GM,Singer GA,Rawls WH,Siddiky MA

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:The serum CA-125 antigen value has proven to be useful in predicting changes that affect prognosis and management of ovarian cancer; however, interpreting variations in the tumor marker is still not well-defined. Our goal was to further understand the analytical variability of CA-125 in a conventional hospit...

journal_title：Gynecologic oncology

authors： Tso E,Elson P,Vanlente F,Markman M

更新日期：2006-10-01 00:00:00

abstract：:The cell line HTOA was established from a well-differentiated human ovarian serous cystadenocarcinoma. This line grew well and without interruption for 51 months and was subcultivated over 130 times. The cells were epithelial in shape, and neoplastic and pleomorphic features, a jigsaw puzzle-like arrangement, desmosom...

journal_title：Gynecologic oncology

authors： Ishiwata I,Ishiwata C,Soma M,Nozawa S,Ishikawa H

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to determine whether ovarian preservation is feasible in younger endometrial cancer patients. METHODS:Endometrial cancer patients who underwent ovary-saving surgery were recruited from the tumor registries of 14 tertiary hospitals under the influence of the Korean Gynecologic...

journal_title：Gynecologic oncology

authors： Lee TS,Kim JW,Kim TJ,Cho CH,Ryu SY,Ryu HS,Kim BG,Lee KH,Kim YM,Kang SB,Korean Gynecologic Oncology Group.

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:To determine which patients with locoregionally advanced endometrial cancer may benefit from pelvic external beam radiotherapy (EBRT) in addition to chemotherapy compared to chemotherapy alone. METHODS:Patients with FIGO stages III-IVA endometrial carcinoma between 2004 and 2016 who underwent at least total...

journal_title：Gynecologic oncology

authors： Xiang M,English DP,Kidd EA

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:In this study, we analyzed the PTEN expression in a large collection of clear cell adenocarcinomas of the ovary. Furthermore, we analyzed the expression of cyclin D1 and p27, and investigated the correlation among all these variables. METHODS:Totally, 40 clear cell adenocarcinomas were included in this stud...

journal_title：Gynecologic oncology

authors： Hashiguchi Y,Tsuda H,Inoue T,Berkowitz RS,Mok SC

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the effect of number of chemotherapy cycles and other clinical and pathologic factors on progression-free (PFS) and overall survival (OS) in patients with newly diagnosed cervical cancer. METHODS:We identified 118 patients with locally advanced cervical cancer (stages I...

journal_title：Gynecologic oncology

authors： Nugent EK,Case AS,Hoff JT,Zighelboim I,DeWitt LL,Trinkhaus K,Mutch DG,Thaker PH,Massad LS,Rader JS

更新日期：2010-03-01 00:00:00

abstract：:Forty patients with locally advanced cervical carcinoma were entered into a protocol utilizing the bolus administration of both mitomycin C (10 or 15 mg) on Day 1 and 5-fluorouracil (400 mg) on Day 1-5 followed by sequential pelvic irradiation on Day 6 between September 1980 and October 1985. All patients had poor-pro...

journal_title：Gynecologic oncology

authors： Denehy TR,Eastman R,SanFilippo L,Gregori CA,Breen JL

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To assess the treatment and outcome of patients with endometrial cancer following isolated pulmonary relapse. METHODS:Between 1984 and 1996, 82 of 1109 patients undergoing surgery for primary endometrial cancer experienced a primary pulmonary recurrence, 28 of which were solitary. Median follow up of censore...

journal_title：Gynecologic oncology

authors： Dowdy SC,Mariani A,Bakkum JN,Cliby WA,Keeney GL,Podratz KC

更新日期：2007-11-01 00:00:00

abstract：:Surgical assessment of aortocaval lymph nodes in patients with unresectable primary cervical cancer helps in planning radiation treatment ports. Removal of enlarged lymph nodes may also serve a therapeutic purpose in reducing the tumor load to be sterilized by radiation. An extraperitoneal dissection is considered to ...

journal_title：Gynecologic oncology

authors： Vasilev SA

更新日期：1995-02-01 00:00:00

abstract：:Clear-cell hidradenocarcinoma is a malignant tumor of sweat gland origin. It is most often found on the trunk, head, and extremities. This case report describes a rare occurrence of this tumor on the vulva of a young woman. The discovery of metastatic disease reflects the potentially aggressive nature of this tumor. ...

journal_title：Gynecologic oncology

authors： Messing MJ,Richardson MS,Smith MT,King L,Gallup DG

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Survivorship and quality of life issues are becoming increasingly relevant in endometrial cancer as a result of the marked increase in incidence of the disease combined with excellent and improving long term survival. OBJECTIVE:The purpose of this study was to evaluate the effect of obesity on quality of li...

journal_title：Gynecologic oncology

authors： Smits A,Lopes A,Das N,Bekkers R,Galaal K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Granulosa cell tumors of the ovary are rare, primarily treated surgically. In advanced or recurrent disease, data are inconclusive regarding the benefit of either primary or adjuvant chemotherapy. Hormonal therapy has been suggested as an alternative treatment. CASE:Our patient had three recurrences of estr...

journal_title：Gynecologic oncology

authors： Hardy RD,Bell JG,Nicely CJ,Reid GC

更新日期：2005-03-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) of the vulva is a rare, low- to intermediate-grade sarcoma of dermal origin. This case report represents the 13th reported patient with vulvar DFSP and the first reported patient with metastatic vulvar DFSP. Although metastasis is rare, the possibility remains that the frequent r...

journal_title：Gynecologic oncology

authors： Soergel TM,Doering DL,O'connor D

更新日期：1998-11-01 00:00:00

abstract：:The causes of death in long-term survivors after resection of cervical cancer were investigated in a follow-up study of 375 women, focusing especially on the postoperative development of second primary cancers. The 5- and 10-year overall survival rates were 75.0 and 66.0%, respectively, in cases that showed frank inva...

journal_title：Gynecologic oncology

authors： Tominaga K,Koyama Y,Sasagawa M,Obata N,Kamata H,Yamaguchi E,Nagai M

更新日期：1995-01-01 00:00:00