Abstract:
AIMS:Fecal incontinence (FI) is embarrassing, resulting in poor quality of life. Rectal sensation may be more important than sphincter strength to relieve symptoms. A single-blind, randomized controlled trial among adults with FI compared the effectiveness of rectal balloon training (RBT) and pelvic floor muscle training (PFMT) versus PFMT alone. METHODS:We randomized 80 patients, recruited from the Maastricht University Medical Centre. Primary outcome was based on the Vaizey score. Secondary outcomes were the Fecal Incontinence Quality of Life Scale (FIQL), 9-point global perceived effect (GPE) score, anorectal manometry, rectal distension volumes, and thresholds of anorectal sensation. Analyses were by intention-to-treat. RESULTS:Forty patients were assigned to combined RBT with PFMT and 40 to PFMT alone. Adding RBT did not result in a significant improvement in the Vaizey score [mean difference: -1.19; 95% confidence interval (CI): -3.79 to 1.42; P = 0.37]. Secondary outcomes favoring RBT were: Lifestyle subscale of the FIQL (0.37; 95% CI: 0.02-0.73; P = 0.04), GPE (-1.01; 95% CI: -1.75 to -0.27; P = 0.008), maximum tolerable volume (49.35; 95% CI: 13.26-85.44; P = 0.009), and external anal sphincter fatigue (0.65; 95% CI: 0.26-1.04; P = 0.001). Overall, 50% of patients were considered improved according to the estimated minimally important change (Vaizey change ≥-5). CONCLUSIONS:RBT with PFMT was equally effective as PFMT alone. Secondary outcomes show beneficial effects of RBT on urgency control, GPE, and lifestyle adaptations. Characteristics of patients who benefit most from RBT remain to be confirmed.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Bols E,Berghmans B,de Bie R,Govaert B,van Wunnik B,Heymans M,Hendriks E,Baeten Cdoi
10.1002/nau.21218subject
Has Abstractpub_date
2012-01-01 00:00:00pages
132-8issue
1eissn
0733-2467issn
1520-6777journal_volume
31pub_type
杂志文章,随机对照试验abstract:AIMS:Pelvic organ prolapse occurs in 50% of parous women. Laparoscopic sacrocolpopexy (LSCP) is a common surgical procedure for restoring pelvic anatomy and function. The aim of this study is to evaluate surgical anatomy and anatomical modifications induced by standardized LSCP. METHODS:Ten fresh female cadavers under...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22806
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abstract:AIMS:Individuals with spinal cord injury or neurological disorders may develop bladder contractions at low volumes (neurogenic detrusor overactivity), which can lead to significant health problems. Present devices can inhibit unwanted contractions through continuous electrical stimulation of sensory nerves, but do not ...
journal_title:Neurourology and urodynamics
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abstract:AIM:To explore the effects of experimental subarachnoid hemorrhage (SAH) on rabbit urinary bladder and to assess the potential protective effects of hyperbaric oxygen therapy (HBOT). METHODS:A total of 15 male New Zealand white rabbits were divided randomly to one of three groups: group I was spared as the control gro...
journal_title:Neurourology and urodynamics
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doi:10.1002/nau.24418
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abstract:AIMS:Percutaneous tibial nerve stimulation (PTNS) is an effective neuromodulation therapy for treating overactive bladder (OAB). The therapeutic effects are achieved by repeatedly applying electrical stimulation through a percutaneous needle electrode that is used to target the tibial nerve (TN). Anatomical studies ind...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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abstract:AIMS:To report the state of the science on primary prevention of urinary incontinence (UI) in adults from the 6th International Consultation on Incontinence with an update through January 2019. METHODS:Online databases PubMed, CINAHL, PsycInfo, and Medline were searched in March 2016 and February 2019 with a focus on ...
journal_title:Neurourology and urodynamics
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析
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abstract::In the last two decades, nerve growth factor (NGF), initially described as a prototypical trophic factor in the development of sensory and sympathetic innervation, has emerged as a complex regulator of neural plasticity along the micturition pathways. This review aims to summarize the current experimental and clinical...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
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journal_title:Neurourology and urodynamics
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pub_type: 临床试验,杂志文章
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journal_title:Neurourology and urodynamics
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00
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journal_title:Neurourology and urodynamics
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更新日期:2005-01-01 00:00:00
abstract::It is well known that urethane is a suitable anesthetic for acute studies and has been extensively recommended for investigations related to micturition physiology. This is mainly because of the capability of urethane anesthesia to spare reflex micturition as well as its easily established long-lasting and stable anes...
journal_title:Neurourology and urodynamics
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doi:10.1002/(sici)1520-6777(2000)19:1<87::aid-nau9>3.0
更新日期:2000-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章,多中心研究
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abstract::Abnormalities of micturition occur in many different diseases, have a variety of causes and take several forms. This review will focus exclusively on those abnormalities in which antidiuretic therapy may be of benefit. These conditions are primarily characterized by an increase in the total amount of urine produced (p...
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更新日期:2007-01-01 00:00:00
abstract:AIMS:To evaluate neuromodulation outcomes in patients with prior back surgery. METHODS:Adults in our prospective observational sacral/pudendal neuromodulation study were retrospectively evaluated. History and operative details were reviewed, and outcomes were measured at 3, 6, 12, and 24 months with overactive bladder...
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pub_type: 杂志文章,随机对照试验
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journal_title:Neurourology and urodynamics
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