A tumultuous transition to motherhood: Altered brain and hormonal responses in mothers with postpartum depression.

abstract：:The present study examined whether a transient thyroid hormone (T(4)) deficit during infancy in male monkeys would compromise the arrest of luteinising hormone (LH) secretion during the infant-juvenile transition, and/or interfere with the pubertal resurgence of LH. Animals were orchidectomized and thyroidectomized (n...

journal_title：Journal of neuroendocrinology

authors： Plant TM,Ramaswamy S,Bhat GK,Stah CD,Pohl CR,Mann DR

更新日期：2008-10-01 00:00:00

abstract：:Humans have engineered a dietary environment that has driven the global prevalence of obesity and several other chronic metabolic diseases to pandemic levels. To prevent or treat obesity and associated comorbidities, it is crucial that we understand how our dietary environment, especially in combination with a sedenta...

journal_title：Journal of neuroendocrinology

authors： Slomp M,Belegri E,Blancas-Velazquez AS,Diepenbroek C,Eggels L,Gumbs MCR,Joshi A,Koekkoek LL,Lamuadni K,Ugur M,Unmehopa UA,la Fleur SE,Mul JD

更新日期：2019-05-01 00:00:00

abstract：:Previous studies have shown that galanin plays an important role in the regulation of gonadotropin releasing hormone (GnRH) release. At present, it is not known if this role is exerted by direct or indirect interactions between galanin producing neurones and GnRH neurones. The objective of this study was to determine ...

journal_title：Journal of neuroendocrinology

authors： Mitchell V,Bouret S,Prévot V,Jennes L,Beauvillain JC

更新日期：1999-10-01 00:00:00

abstract：:Folate is an important regulator of hippocampal neurogenesis, and folic acid is needed prenatally to reduce the risk of neural tube defects. Both high levels of folic acid and low levels of folate can be harmful to health because low levels of folate have been linked to several diseases while high folic acid supplemen...

journal_title：Journal of neuroendocrinology

authors： Qiu W,Gobinath AR,Wen Y,Austin J,Galea LAM

更新日期：2019-10-01 00:00:00

abstract：:The anteroventral periventricular nucleus (AVPV) is sexually dimorphic, presenting a higher neuronal density in females. The AVPV contains a dense collection of oestrogen and progesterone receptors and has been related to the modulation of gonadotrophin-releasing hormone (GnRH) secretion and gene expression in respons...

journal_title：Journal of neuroendocrinology

authors： Valera AG,Cavalcante JC,Elias CF,Felício LF

更新日期：2006-09-01 00:00:00

abstract：:Activation of adenylate cyclase induces cultured neurohypophysial astrocytes (pituicytes) to change from a protoplasmic, nonstellate form to a stellate form. Stellation is inhibited and reversed (destellation) by serum. The objective of the present studies was to examine the roles of Ca2+ and tyrosine phosphorylation ...

journal_title：Journal of neuroendocrinology

authors： Ramsell KD,Cobbett P

更新日期：2000-10-01 00:00:00

abstract：:Visceral inputs to the brain make their initial synapses within the nucleus of the solitary tract (NTS), where information is relayed to other brain regions. These inputs relate to markedly different physiological functions and provide a tool for investigating the topography of visceral processing in brainstem nuclei....

journal_title：Journal of neuroendocrinology

authors： Mayne RG,Armstrong WE,Crowley WR,Bealer SL

更新日期：1998-11-01 00:00:00

abstract：:Carbetocin, a long-acting oxytocin analogue, has been reported to elicit interesting and peculiar behavioural effects. The present study investigated the molecular pharmacology of carbetocin, aiming to better understand the molecular basis of its action in the brain. Using bioluminescence resonance energy transfer bio...

journal_title：Journal of neuroendocrinology

authors： Passoni I,Leonzino M,Gigliucci V,Chini B,Busnelli M

更新日期：2016-04-01 00:00:00

abstract：:To study the mechanism by which monochromatic light affects gonadotrophin-releasing hormone (GnRH) expression in chicken hypothalamus, a total of 192 newly-hatched chicks were divided into intact, sham-operated and pinealectomy groups and exposed to white (WL), red (RL), green (GL) and blue (BL) lights using a light-e...

journal_title：Journal of neuroendocrinology

authors： Zhang L,Chen F,Cao J,Dong Y,Wang Z,Hu M,Chen Y

更新日期：2017-05-01 00:00:00

abstract：:There is no information on the neuroanatomical distribution of the progesterone receptor (PR) in the rabbit. Therefore, we mapped the distribution of PR-immunoreactive cells in the forebrain of ovariectomized female rabbits. Vehicle-injected ovariectomized rabbits showed PR-immunoreactive cells only in the infundibula...

journal_title：Journal of neuroendocrinology

authors： Caba M,Rovirosa MJ,Beyer C,González-Mariscal G

更新日期：2003-09-01 00:00:00

abstract：:Corticotropin-releasing factor and arginine vasopressin (AVP) are the two major hypothalamic factors that regulate anterior pituitary adrenocorticotropin secretion during stress. We have previously reported that the expression of the corticotröpin-releasing factor gene in the hypothalamus and its regulation by glucoco...

journal_title：Journal of neuroendocrinology

authors： Grino M,Burgunderf JM

更新日期：1992-02-01 00:00:00

abstract：:Abstract The presence and distribution of angiotensinogen and angiotensin II (All) were demonstrated in rat pituitary by immunocytochemical staining with the avidin-biotin-peroxidase method, using primary polyclonal antibodies specific for angiotensinogen and All. Silver enhancement of the reaction product was used to...

journal_title：Journal of neuroendocrinology

authors： Thomas WG,Sernia C

更新日期：1990-06-01 00:00:00

abstract：:This study examined the immunolocalization and ontogeny of the inhibin-specific alpha subunit in the brain of male rats. Immunohistochemistry using antiserum directed against the mature region of porcine inhibin alpha (1-19, Tyr20) revealed positive reactions in process-bearing cells resembling astroglia in several re...

journal_title：Journal of neuroendocrinology

authors： Fujimura H,Ohsawa K,Funaba M,Murata T,Murata E,Takahashi M,Abe M,Torii K

更新日期：1999-03-01 00:00:00

abstract：:Recently, we described that free corticosterone levels in the brain of male Wistar rats, as assessed by in vivo microdialysis, show an ultradian rhythm with a pulse frequency of 1.2 pulses/h. To establish whether gender influences brain free corticosterone rhythms, we studied free corticosterone levels in the female W...

journal_title：Journal of neuroendocrinology

authors： Droste SK,de Groote L,Lightman SL,Reul JM,Linthorst AC

更新日期：2009-02-01 00:00:00

abstract：:The annual breeding cycle of 'unimproved' breeds of domestic chicken, including the bantam, at temperate latitudes, is terminated by decreasing daylength in autumn and is initiated in late winter, while daylengths are still short. Observations on photoperiodic birds that terminate seasonal breeding by the development ...

journal_title：Journal of neuroendocrinology

authors： Sreekumar KP,Sharp PJ

更新日期：1998-02-01 00:00:00

abstract：:An understanding of the functional significance of the newly identified estrogen receptor (ER beta) in the brain will require definition of its expression pattern and relationship to ER alpha. Using an antibody generated against the C-terminus of rat ER beta, we report the presence of ER beta immunoreactivity in the l...

journal_title：Journal of neuroendocrinology

authors： Simonian SX,Herbison AE

更新日期：1997-11-01 00:00:00

abstract：:Preterm labour and birth can be delayed but are generally unstoppable, threatening the health of the mother-baby duo. This may be a result of peripheral signals prematurely recruiting the oxytocin neurones that co-ordinate the timing of birth and, via specialised activity and secretion patterns, drive uterine contract...

journal_title：Journal of neuroendocrinology

authors： Douglas AJ

更新日期：2010-09-01 00:00:00

abstract：:Aldosterone has been reported to impair the baroreflex response in animal models. The present study aimed to investigate the acute effects of aldosterone on the autonomic nervous system and the baroreflex control of muscle sympathetic nerve activity (MSNA) and heart rate in healthy humans. Nine healthy subjects were e...

journal_title：Journal of neuroendocrinology

authors： Heindl S,Holzschneider J,Hinz A,Sayk F,Fehm HL,Dodt C

更新日期：2006-02-01 00:00:00

abstract：:There are three paralogous genes for gonadotrophin-releasing hormone (GnRH) peptides of vertebrates in general. GnRH1, the protein product of gnrh1 gene, is the hypophysiotrophic neuropeptide, and is a critical regulator of gonadotrophin secretion, whereas GnRH2 and GnRH3 are regarded to have neuromodulatory functions...

journal_title：Journal of neuroendocrinology

authors： Akazome Y,Kanda S,Oka Y

更新日期：2011-07-01 00:00:00

abstract：:Several interleukins have been reported to play a major role in the regulation of steroid secretion at all three levels of the hypothalamic-pituitary-adrenal axis. The objective of this study was to investigate the effect of interleukin-3 (IL-3) and interleukin-6 (IL-6) on cortisol secretion of bovine adrenocortical c...

journal_title：Journal of neuroendocrinology

authors： Michl P,Beikler T,Engelhardt D,Weber MM

更新日期：2000-01-01 00:00:00

abstract：:Metabotropic glutamate receptor subtype 7 (mGluR7) is one of the group III mGluRs, which are negatively coupled to adenylate cyclase via Gi/Go proteins and localised to presynaptic active zones of the mammalian central nervous system. We previously reported that mGluR7 is essential for intermale aggression and amygdal...

journal_title：Journal of neuroendocrinology

authors： Masugi-Tokita M,Yoshida T,Kageyama S,Kawata M,Kawauchi A

更新日期：2018-03-01 00:00:00

abstract：:Postpartum depression affects 15% of new mothers and previous depressive episodes increase the risk for postpartum depression. Chronic administration of corticosterone (CORT) to dams during the postpartum period causes depressive-like behaviour and has been used as a model of postpartum depression. To better understan...

journal_title：Journal of neuroendocrinology

authors： Wong JH,Brummelte S,Galea LA

更新日期：2011-11-01 00:00:00

abstract：:Subclinical hypothyroidism (SCH) is characterized by mild elevation of thyroid stimulating hormone (TSH) (range 5-10 μIU/ml) and normal free triiodothyronine (FT3) and free thyroxine (FT4). The cognitive function impairment is well known in thyroid disorders such as hypothyroidism and hyperthyroidism, but little is kn...

journal_title：Journal of neuroendocrinology

authors： Kumar M,Modi S,Rana P,Kumar P,Kanwar R,Sekhri T,D'souza M,Khushu S

更新日期：2018-03-05 00:00:00

abstract：:Acute illness in mice profoundly affects thyroid hormone metabolism in the hypothalamus and pituitary gland. It remains unknown whether the thyroid hormone receptor (TR)-β is involved in these changes. In the present study, we investigated central thyroid hormone metabolism during lipopolysaccharide (LPS)-induced illn...

journal_title：Journal of neuroendocrinology

authors： Boelen A,Kwakkel J,Chassande O,Fliers E

更新日期：2009-05-01 00:00:00

abstract：:The central nervous system regulates and responds to endocrine signals, and this reciprocal relationship determines emotional processing and behavioural anxiety. Although the hypothalamic-pituitary-adrenal (HPA) axis remains the best-characterised system for this relationship, other steroid and peptide hormones are in...

journal_title：Journal of neuroendocrinology

authors： Borrow AP,Stranahan AM,Suchecki D,Yunes R

更新日期：2016-07-01 00:00:00

abstract：:Glucocorticoid hormones are particularly potent with respect to enhancing memory formation. Notably, this occurs in close synergy with arousal (i.e., when norepinephrine levels are enhanced). In the present study, we examined whether glucocorticoid and norepinephrine hormones regulate the number of spines in hippocamp...

journal_title：Journal of neuroendocrinology

authors： Lesuis SL,Timmermans W,Lucassen PJ,Hoogenraad CC,Krugers HJ

更新日期：2020-01-01 00:00:00

abstract：:The mechanisms of action of glucocorticoid hormones are mediated via specific intracellular receptor proteins. The glucocorticoid receptor (GR) regulates expression of specific target genes or gene networks by ligand-dependent transcriptional activation, i.e. ligand-dependent activation of the receptor with subsequent...

journal_title：Journal of neuroendocrinology

authors： Brönnegård M,Stierna P,Marcus C

更新日期：1996-06-01 00:00:00

abstract：:Leptin plays a major role in coordinating the integrated response of the brain to changes in nutritional state. Leptin receptor expressing neurones within the arcuate nucleus (ARC) of the hypothalamus sense circulating leptin and densely innervate other regions of the hypothalamus, including the paraventricular nucleu...

journal_title：Journal of neuroendocrinology

authors： Jovanovic Z,Tung YC,Lam BY,O'Rahilly S,Yeo GS

更新日期：2010-08-01 00:00:00

abstract：:In the female rat, oestrogen receptor (ER) beta is colocalized with both oxytocin- and vasopressin-producing neurones in the paraventricular nucleus of the hypothalamus (PVN). In this study, we demonstrate that the same pattern of colocalization between ERbeta and oxytocin exists in the female mouse. Because this nucl...

journal_title：Journal of neuroendocrinology

authors： Patisaul HB,Scordalakes EM,Young LJ,Rissman EF

更新日期：2003-08-01 00:00:00

abstract：:In lactating nursing vs lactating pup-deprived mice, single or multiple immunolabeling was performed to compare immunoreactivities (ir) for neuropeptide Y (NPY), enkephalins (ENK) and neurotensin (NT) in the tyrosine hydroxylase (TH)-ir (ENK) and neurotensin (NT) in the tyrosine hydroxylase (TH)-ir hypothalamic tubero...

journal_title：Journal of neuroendocrinology

authors： Ciofi P,Crowley WR,Pillez A,Schmued LL,Tramu G,Mazzuca M

更新日期：1993-12-01 00:00:00