Febrile ulceronecrotic Mucha-Habermann disease with central nervous system vasculitis.

Abstract:

:Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a severe variant of pityriasis lichenoides et varioliformis acuta (PLEVA). We report a case of FUMHD in an 11-year-old boy who subsequently developed neurologic symptoms and was found to have necrotizing vasculitis on brain biopsy. Over 5 years of follow-up, he had one biopsy-proven recurrence of his skin lesions and continued rehabilitation and treatment for residual neurologic complications. This case provides histological evidence of central nervous system vasculitis associated with FUMHD. Our patient's disease was eventually controlled with cyclophosphamide.

journal_name

Pediatr Dermatol

journal_title

Pediatric dermatology

authors

Rosman IS,Liang LC,Patil S,Bayliss SJ,White AJ

doi

10.1111/j.1525-1470.2011.01669.x

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

90-3

issue

1

eissn

0736-8046

issn

1525-1470

journal_volume

30

pub_type

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