LINC01116 promotes proliferation, invasion and migration of osteosarcoma cells by silencing p53 and EZH2.

abstract：OBJECTIVE:Nasopharyngeal carcinoma (NPC) is one of the most ordinary malignant tumors. Recent studies have revealed that circular RNAs play an important role in the progression of tumorigenesis. This study aims to identify how circular RNA_LARP4 functions in the progression of NPC. PATIENTS AND METHODS:We performed Re...

journal_title：European review for medical and pharmacological sciences

authors： Pan JY,Bao XL,Zhu K

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Urogenital atrophy is a degenerative process that may occur during menopause causing debilitating disorders and painful symptomatology. Estrogen therapy slows the onset of atrophy, but it requires ongoing therapy to maintain its effectiveness. To mitigate the degenerative evolutions associated with menopause,...

journal_title：European review for medical and pharmacological sciences

authors： Casarotti GA,Chiodera P,Tremolada C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To explore the lesion patterns and stroke mechanism of the acute bilateral cerebellar infarct. PATIENTS AND METHODS:Patients admitted to Xiangyang Hospital with acute cerebellar infarcts, confirmed by diffusion-weighted imaging (DWI), were investigated. Patients were divided into two groups by lesions: unila...

journal_title：European review for medical and pharmacological sciences

authors： Wang PQ,Ding ZG,Zhang GB,Wang Y,Liu JZ

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To explore the effect of carbachol on myocardial injury in septic rats, and to further study its influence on the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway. MATERIALS AND METHODS:A total of 48 healthy male Sprague-Dawley rats were randomly divided into sham group (n=16), m...

journal_title：European review for medical and pharmacological sciences

authors： Zhou L,Jiang ZM,Qiu XM,Zhang YK,Zhang FX,Wang YX

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:To identify laboratory markers among platelet indices, coagulation parameters, blood lipid parameters, and liver/kidney function variables that can be used to predict preeclampsia. PATIENTS AND METHODS:We studied records of 568 women with preeclampsia, gestational hypertension (GH), or normal term pregnancie...

journal_title：European review for medical and pharmacological sciences

authors： Han Q,Zheng W,Guo XD,Zhang D,Liu HF,Yu L,Yan JY

更新日期：2020-07-01 00:00:00

abstract：:Secondary or pathologic fractures, associated with osteosarcoma, have been considered for a long time to be a negative prognosis regarding its evolution in the patients. The aim of this study was to evaluate the prognostic importance of such pathologic fractures in osteosarcoma patients receiving new therapies as well...

journal_title：European review for medical and pharmacological sciences

authors： Vermesan D,Vermesan H,Dragulescu SI,Bera I,Di Giovanni A,Sabatini R,Santacroce L,Bottalico L,Flace P,Cagiano R

更新日期：2009-03-01 00:00:00

abstract：:Angioleiomyoma (AL) is a benign neoplasia originating from smooth muscle and very uncommon in the oral cavity. The most frequent subtype in the oral cavity is the vascular one. AL usually occurs in the extremities: only around 12% are found in other areas such as head and neck. It presents as an asymptomatic, slow gro...

journal_title：European review for medical and pharmacological sciences

authors： Minni A,De Carlo A,Roukos R,Illuminati G,Cerbelli B

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to explore the role of miR-155-5p in middle cerebral artery occlusion/reperfusion (MCAO/R) model in rats and oxygen-glucose deprivation/reoxygenation (OGD/R)-induced SH-SY5Y cells. In addition, this study also aimed to explore the underlying mechanisms to expect that miR-155-5p may be investi...

journal_title：European review for medical and pharmacological sciences

authors： Shi Y,Li K,Xu K,Liu QH

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to explore whether long non-coding RNA AGAP2-AS1 (AGAP2-AS1) could serve as a novel biomarker for non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS:Cancer and matched normal lung tissues were collected from 198 patients. AGAP2-AS1 levels were examined by RT-PCR, and the a...

journal_title：European review for medical and pharmacological sciences

authors： Fan KJ,Liu Y,Yang B,Tian XD,Li CR,Wang B

更新日期：2017-05-01 00:00:00

abstract：:Liver fibrosis involves different cell types, and should be regarded as a "wound healing" response that occurres in conditions of chronic liver injury and is characterized by inflammation, activation of matrix-producing cells, matrix deposition and remodeling, and epithelial cell regeneration or an attempt thereof. Li...

journal_title：European review for medical and pharmacological sciences

authors： Marra F,Aleffi S,Bertolani C,Petrai I,Vizzutti F

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:To this date, only a small number of studies have described the long-term use of BTX in Hemifacial spasm. AIM:To assess the prognosis and long-term effectiveness of Botulinum toxin A (BTXA) in the treatment of unilateral spasms of the eyelid. PATIENTS AND METHODS:From September 1998 to January 2006, 245 co...

journal_title：European review for medical and pharmacological sciences

authors： Xu YP,Shen J,Zhu QB,Gu J,Lin SZ,Fan JP

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:This study aimed to characterize the effect of Twist2 on epithelial-to-mesenchymal transition (EMT) and the invasive potential of colorectal cancer (CRC) cells and to explore the mechanisms underlying the regulative effect of Twist1 and Twist2 on matrix metalloproteinase 2 (MMP2) expression in CRC. PATIENTS ...

journal_title：European review for medical and pharmacological sciences

authors： Lu K,Dong JL,Fan WJ

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between the acute myocardial infarction (AMI) complicated with cerebral infarction (CI) and expression levels of matrix metalloproteinase-2 (MMP-2) and MMP-9. PATIENTS AND METHODS:A total of 50 AMI patients treated in our hospital were enrolled, including 23 AMI patients compli...

journal_title：European review for medical and pharmacological sciences

authors： Zhou L,Kou DQ

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:We aimed to assess the preoperative rectal cancer angiogenesis with Endorectal Power Doppler Ultrasonography by using the Power Doppler Vascularity Index (PDVI) calculated by imaging analysis software, and to compare it with the microvessel density (MVD) in surgical specimens PATIENTS AND METHODS: This study ...

journal_title：European review for medical and pharmacological sciences

authors： Tankova L,Nakov R,Stoilov G,Gegova A,Nakov V,Gerova V,Terziev I,Kovatchki D

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To investigate the role of phosphatidylinositol-3-kinase protein kinase B (PI3K/Akt) signaling pathway in the apoptosis of H1299 lung cancer cells induced by epigallocatechin gallate (EGCG). MATERIALS AND METHODS:H1299 lung cancer cells were treated with EGCG at a dose of 10 µM, 20 µM, and 40 µM, respectivel...

journal_title：European review for medical and pharmacological sciences

authors： Gu JJ,Qiao KS,Sun P,Chen P,Li Q

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Renal cell carcinoma (RCC) is the most common cancer of the kidney. Despite advances in treatment, 5-year survival rate for metastatic RCC is estimated to be less than 10%. Thus, new therapeutic options for RCC are urgently needed. AIM:In this study, our objective here was to identify a set of discriminatin...

journal_title：European review for medical and pharmacological sciences

authors： Lou S,Ren L,Xiao J,Ding Q,Zhang W

更新日期：2012-06-01 00:00:00

abstract：:The purpose of this pictorial essay is to describe anatomic variants and congenital anomalies of portal venous system and related liver parenchymal alterations. The imaging findings of some of these entities have been previously described in other articles, however this work encompasses all congenital anomalies of por...

journal_title：European review for medical and pharmacological sciences

authors： Guerra A,De Gaetano AM,Infante A,Mele C,Marini MG,Rinninella E,Inchingolo R,Bonomo L

更新日期：2017-10-01 00:00:00

abstract：:Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Downregulation of lncRNA SNHG7 inhibits proliferation and invasion of nasopharyngeal carcinoma cells through repressing ROCK1, by L. Wang, T. Xu, X. Cui, ...

journal_title：European review for medical and pharmacological sciences

authors： Wang L,Xu T,Cui X,Han M,Zhou LH,Wei ZX,Xu ZJ,Jiang Y

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Recent researches have revealed the role of long noncoding RNAs (lncRNAs) in tumor development. In this study, the potential function of lncRNA LUCAT1 in the progression of prostate cancer was identified. PATIENTS AND METHODS:Real Time-quantitative Polymerase Chain Reaction (RT-qPCR) was used to detect LUCAT...

journal_title：European review for medical and pharmacological sciences

authors： Liu C,Wang L,Li YW,Cui YS,Wang YQ,Liu S

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Chemoresistance is the principal reason for poor survival and disease recurrence in osteosarcoma patients. Survivin, a family member of the inhibitor of apoptosis proteins, plays an important role in inhibition of apoptosis. Survivin is expressed in a vast majority of human cancers, which is often correlated ...

journal_title：European review for medical and pharmacological sciences

authors： Gao JZ,Chen FH,Wang L,Wei H,Meng SL

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To clarify the role of microRNA-183-5p in the malignant progression of osteosarcoma (OS) and the potential mechanism. PATIENTS AND METHODS:Relative level of microRNA-183-5p in 40 paired OS tissues and matched normal tissues was determined by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). Correla...

journal_title：European review for medical and pharmacological sciences

authors： Shao JH,Yuan S,Qian QR,Zhu J

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Coronavirus disease 2019 (COVID-19) has officially been declared a pandemic by the World Health Organization (WHO). Radiological examinations, especially computed tomography (CT), play an important role in the fight against COVID-19. A comprehensive and timely review of radiological role in the fight against ...

journal_title：European review for medical and pharmacological sciences

authors： Hu L,Wang C

更新日期：2020-04-01 00:00:00

abstract：:In the last 25 years, obesity has reached epidemic levels of prevalence. It has even affected the children such that rates of severe childhood obesity that have almost tripled in numbers. These numbers are alarming because of the known fact that obesity is associated with an increased risk of several comorbidities as ...

journal_title：European review for medical and pharmacological sciences

authors： Xiao T,Fu YF

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Acute pancreatitis (AP) is an inflammatory disease of the pancreas characterized by local inflammation. Secretory phospholipases A-II (sPLA2-II) have been implicated in triggering AP, but their exact role to evoke AP is largely unknown. NF-kB activation has previously been shown to induce acute pancreatitis....

journal_title：European review for medical and pharmacological sciences

authors： Zhang MS,Zhang KJ,Zhang J,Jiao XL,Chen D,Zhang DL

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Hepatocarcinoma is a great threat to global health. MicroRNA-23a was suggested to regulate growth and apoptosis in certain cell lines. Our study was focused on growth, proliferation, and apoptosis of hepatocarcinoma cell line MHCC97H under the influence of microRNA-23a, and explored the mechanism of pro-apopt...

journal_title：European review for medical and pharmacological sciences

authors： Ji DG,Jiang CW,Luo X,Liu Z,Huang WJ,Zhang XH,Yu TH,Zhang LR

更新日期：2018-09-01 00:00:00

abstract：:Antinuclear antibodies (ANA) represent the main diagnostic markers for systemic autoimmune disease (AD), although their presence can be detected in blood donors. The aim of this study was to study ANA prevalence in healthy subjects of different racial groups, exposed to the same environmental factors, in order to unde...

journal_title：European review for medical and pharmacological sciences

authors： Cacciapaglia F,Arcarese L,Rigon A,Vadacca M,Valorani MG,Pozzilli P,Afeltra A

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancers globally. LncRNA HLA complex group 11 (HCG11) has been reported to play an oncogenic role in multiple cancers. Nevertheless, the role and regulatory mechanism of HCG11 in HCC are not fully addressed. PATIENTS AND METHODS:The abundan...

journal_title：European review for medical and pharmacological sciences

authors： Li ML,Zhang Y,Ma LT

更新日期：2019-12-01 00:00:00

abstract：:Non-Muscle-Invasive-Bladder-Cancer represents 75-85% of the new bladder cancer cases per year. Trans-uretral vesical resection is the milestone for diagnosis and therapy. After primary treatment, recurrence is frequent depending on the presence of several established risk factors: multiplicity, T dimension, prior recu...

journal_title：European review for medical and pharmacological sciences

authors： Leopardo D,Cecere SC,Di Napoli M,Cavaliere C,Pisano C,Striano S,Marra L,Menna L,Claudio L,Perdonà S,Setola S,Berretta M,Franco R,Tambaro R,Pignata S,Facchini G

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:In patients with chronic congenital haemolytic disorders, human Parvovirus B19 (HPV B19) is frequently involved in pure red-cell aplastic crises. Furthermore, it may inhibit three-lineage haematopoiesis in the bone marrow, causing severe pancytopenia. In such patients, Epstein Barr virus (EBV) infection also...

journal_title：European review for medical and pharmacological sciences

authors： Cefalo MG,Arlotta A,Maurizi P,Russo I,Sani I,Battista A,Mastrangelo S,Ruggiero A,Riccardi R

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Micro-ribonucleic acids (miRNAs) are involved in the occurrence of various cancers, and the hypoxia-inducible factor 1-α (HIF-1α) is the main regulator of cell proliferation induced by hypoxia. The relationships of miR-199a and HIF-1α expressions with non-small cell lung cancer (NSCLC) remain unclear, so they...

journal_title：European review for medical and pharmacological sciences

authors： Wang LM,Zhang LL,Wang LW,Zhu L,Ma XX

更新日期：2019-12-01 00:00:00