Abstract:
PURPOSE:Gastric cancer (GC) is a common malignancy, especially in East Asian countries. There is emerging evidence that circulating neutrophil and platelet levels correlate with cancer progression. We evaluated the short- and long-term outcomes of GC patients systemically, to compare the original neutrophil-platelet score (NPS) and our modified NPS (mNPS). METHODS:We analyzed the original pre-operative NPS and the mNPS of 621 GC patients. RESULTS:Racial differences between the United Kingdom and East Asian countries accounted for compelling deviation in classification using the original NPS, which could not reliably stratify the prognoses of Japanese GC patients. We developed the mNPS using appropriate cutoff levels for pre-operative neutrophils and platelets, and demonstrated that the pre-operative mNPS was significantly correlated with all of the well-established clinicopathological factors for disease development, including advanced T stage, venous and lymphatic vessel invasion, lymph node/peritoneal /distant metastasis, and tumor-node-metastasis stage. The pre-operative mNPS could stratify prognostication for both overall survival (OS) and disease-free survival (DFS): a high pre-operative mNPS was an independent prognostic factor for the OS and DFS of GC patients and also an independent predictor of post-operative surgical site infection after gastrectomy. CONCLUSION:Calculating the mNPS could help clinicians to stratify the surgical and oncological risks of patients with GC.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Okugawa Y,Toiyama Y,Yamamoto A,Omura Y,Kusunoki K,Yin C,Ide S,Kitajima T,Koike Y,Fujikawa H,Yasuda H,Okita Y,Hiro J,Yoshiyama S,Ohi M,Araki T,Kusunoki Mdoi
10.1007/s00595-019-01873-ysubject
Has Abstractpub_date
2020-03-01 00:00:00pages
223-231issue
3eissn
0941-1291issn
1436-2813pii
10.1007/s00595-019-01873-yjournal_volume
50pub_type
杂志文章相关文献
SURGERY TODAY文献大全abstract::This study was conducted to examine the effectiveness of the double-stapling technique (DST) for performing esophageal anastomoses. A total of 17 patients, 10 with esophageal cancer and 7 with gastric cancer, underwent esophageal anastomosis employing this technique. Of the ten patients who underwent esophageal operat...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00312390
更新日期:1995-01-01 00:00:00
abstract::A clinical analysis of small-sized lung cancers with advanced disease was conducted on a total of 58 patients: 34 diagnosed as T1N2, 6 as T1N3, 9 as T1M1, and 9 as T4 due to pleural dissemination. The cumulative 5-year survival rate after surgery for the 34 patients with a T1N2 lesion was 17.4%. Of these 34 patients, ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF01676879
更新日期:1994-01-01 00:00:00
abstract::Granulocytic sarcoma is an extramedullary tumor of immature myeloid cells which is often a forerunner to the development of acute myelogenous leukemia. Granulocytic sarcoma of the gastrointestinal tract frequently involves the small intestine and often presents with abdominal pain and obstruction. Our patient presente...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-007-3807-y
更新日期:2009-01-01 00:00:00
abstract::The hemodynamic effect and degree of damage in grafts of single lung transplants for pulmonary hypertension were studied in rats with monocrotaline-induced pulmonary hypertension. Inbred male Lewis rats (weight 200-230 g) were divided into two groups. Group 1 (control group, n = 16) underwent isogenic left lung transp...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF01366939
更新日期:1997-01-01 00:00:00
abstract::Reduction of target coronary artery motion is imperative for successful off-pump coronary artery bypass surgery. We hypothesized that landiolol, a novel ultra-short-acting selective β-1 blocker, would reduce such coronary artery motion. To test this hypothesis, the motion of the left anterior descending artery of the ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-011-0047-y
更新日期:2012-01-01 00:00:00
abstract:PURPOSES:The purpose of this study was to retrospectively analyze the complications arising from stapling of the pulmonary parenchyma and to determine the most appropriate cartridges to use for pulmonary stapling. METHODS:A retrospective multi-institutional review was conducted by the Central Japan Lung Cancer Surgery...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-015-1291-3
更新日期:2016-10-01 00:00:00
abstract::Recently we encountered two cases of early gastric cancer (EGC) with bone metastasis after surgery. As they were not accompanied by overt liver, lung, or peritoneal metastasis, we examined the clinical significance of bone metastasis in EGC and its mechanisms by a review of the literature. We found only 10 cases of EG...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/s00595-010-4389-7
更新日期:2011-02-01 00:00:00
abstract::We report herein the case of a 19-year-old woman, diagnosed as having Klippel-Trenaunay syndrome at the age of 3 years, who presented to our hospital with severe abdominal pain. Abdominal computed tomography revealed splenomegaly, ascites, and paracentesis confirming an intraabdominal hemorrhage. Thus, an emergency la...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311541
更新日期:1995-01-01 00:00:00
abstract::We herein describe two cases of liver transplantation with portal vein thrombosis. In both cases, a tear advancing to the retropancreatic area occurred during portal vein thrombectomy. Hemorrhage from the limited visibility retropancreatic area made it impossible to stop the bleeding by clamping or direct suturing, an...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-013-0647-9
更新日期:2014-04-01 00:00:00
abstract::We report herein the case of a 2-year-old girl with short bowel syndrome who developed chest pain 2 weeks after a totally implantable central venous access catheter had been surgically placed to facilitate total parenteral nutrition. A lateral chest X-ray and contrast flow study subsequently revealed that the catheter...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311442
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:There is still much controversy regarding the optimal treatment for pulmonary contusion. Therefore, we examined the variables affecting patient outcomes over a 10-year period. METHODS:We retrospectively reviewed 107 consecutive patients with a mean age of 28 years, who were treated for pulmonary contusion duri...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-004-2925-z
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Papillary thyroid carcinoma (PTC) frequently metastasizes to and recurs in regional lymph nodes. Of the two compartments, the central compartment can be dissected through the same wound as the thyroidectomy, and the central node dissection (CND) is routinely performed in most Japanese surgical departments. Howe...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-010-4494-7
更新日期:2011-11-01 00:00:00
abstract::We report the case of a patient with pancreatic head cancer, whose replaced common hepatic artery (RCHA) arose from the superior mesenteric artery (SMA). We performed preoperative embolization of the RCHA, after which the liver blood flow was well maintained by the left gastric artery. The patient underwent a radical ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-004-2785-6
更新日期:2004-01-01 00:00:00
abstract::We report a case of primary non-Hodgkin gastric stump lymphoma, found in a 78-year-old man 30 years after a distal gastrectomy for a benign peptic ulcer. The development of lymphoma in the gastric stump is rare. In fact, to our knowledge only 37 cases, including this one, have been documented. Although Helicobacter py...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-006-3234-5
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Ca(2+) channel blockers inhibit collagenase production and have a vasodilatatory effect. They also restrict the formation of ischemia-reperfusion induced free oxygen radicals. The aim of this study was to assess the effect of nifedipine on the healing of colonic anastomoses in a rat model. METHODS:Sixty Wistar...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-003-2633-0
更新日期:2003-01-01 00:00:00
abstract::We investigated the long-term results and ongoing management issues of 39 Japanese children who underwent liver transplantation in Brisbane, Australia. Whole liver grafts were used in 15 patients (Wh group) and reduced-size grafts were used in 24 patients (Re group). The 1-year and 3-year survival rates were 74% and 6...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF01427032
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:In the present study, we investigated the effect of troglitazone, a selective ligand and agonist of PPAR-gamma, on the metastatic potential of human colon cancer cells. METHODS:High- and low-PPAR-gamma expression clones of the colon cancer cell line, HT29, namely clones 21 and 3 respectively, were used. We inv...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950200049
更新日期:2002-01-01 00:00:00
abstract:PURPOSES:The aim of this study was to explore predictive factors for portal or splenic vein thrombosis (VT) that might cause serious problems after distal pancreatectomy (DP). METHODS:A total of 230 patients who underwent DP between 2008 and 2017 were retrospectively reviewed to identify predictive factors for portal ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-020-02004-8
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To clarify the correlation between portal hypertensive gastropathy (PHG) and clinical features after surgery for biliary atresia (BA). METHODS:Routine upper gastrointestinal endoscopies were done over 3 years in 27 children who underwent surgery for BA. We reviewed the recorded endoscopic findings, and retrosp...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-004-2954-7
更新日期:2005-01-01 00:00:00
abstract::We present the case of a 70-year-old man found to have pneumatosis of the small intestine. An abdominal computed tomography (CT) scan detected massive intramural air in the entire circumference of the small intestine without any venous gas. During emergency surgery, 80 cm of the small bowel was removed. The pathologic...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950170178
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Delayed gastric emptying (DGE) is a common complication following left-sided hepatectomy. The goal of this study was to clarify the clinical implications of an omental flap wrapping procedure that includes fixation to the cut surface of the liver to reduce the incidence of DGE after left-sided hepatectomy. ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-012-0446-8
更新日期:2013-12-01 00:00:00
abstract::The efficacy and complications of extracorporeal shock wave lithotripsy (ESWL) for single gallstones were compared between 15 patients with a CT-lucent stone and 18 patients with a dense calcified stone. In all of five patients with a stone smaller than 10 mm in diameter, complete or sufficient clearance was observed,...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00309494
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Soft pancreatic parenchyma is the most widely recognized risk factor for pancreatic fistula. We conducted this study to clarify if there are preoperative factors related to a soft pancreatic remnant and to establish if they are useful for predicting pancreatic fistula. METHODS:This was a retrospective study of...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-014-1045-7
更新日期:2015-06-01 00:00:00
abstract:PURPOSES:To investigate the efficacy of postoperative scheduled intravenous acetaminophen to reduce the opioid use and enhance the recovery after esophagectomy. METHODS:A propensity score-matched population was created using the 93 and 69 consecutive patients who underwent esophagectomy for esophageal cancer before an...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-017-1616-5
更新日期:2018-05-01 00:00:00
abstract::Anastomotic leakage (AL) is a serious but not uncommon complication after colorectal surgery. We conducted this study to evaluate the effect of routine indocyanine green fluorescence angiography (ICG-FA) on reducing the AL rate after colorectal surgery. We identified all research articles about colorectal surgery usin...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/s00595-020-02195-0
更新日期:2021-01-11 00:00:00
abstract:PURPOSE:This study was performed to investigate the effect of subcuticular sutures on the incidence of incisional surgical site infection (SSI) after closure of a diverting stoma. METHODS:The study was carried out as a retrospective analysis of prospectively collected data from 51 patients who underwent closure of div...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-010-4405-y
更新日期:2011-07-01 00:00:00
abstract::We report herein a case of clinically solitary abdominal tuberculoma. A 28-year-old woman was admitted to hospital for treatment of an abdominal tumor shown to be located in the head of the pancreas and compressing the superior mesenteric vein by echosonography and computed tomography (CT). There were no clinical sign...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311262
更新日期:1995-01-01 00:00:00
abstract::Intussusception is uncommon in the proximal gastrointestinal tract, although a few case reports have been published on gastroduodenal intussusception associated with an anatomical abnormality or intussusceptions at a site of gastrojejunostomy after gastric surgery. We herein present a case of gastrogastric intussuscep...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-010-4439-1
更新日期:2011-10-01 00:00:00
abstract::Upper extremity deep vein thrombosis (UEDVT) is an infrequent but dangerous vascular event, especially for patients undergoing thoracic surgery. However, there is no standard perioperative management to reduce the risk of pulmonary thromboembolism in such patients. We describe how we performed successful esophagectomy...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-008-4030-1
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:We investigated whether functional future remnant liver volume (fFRLV), assessed using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (EOB-MRI), could evaluate regional liver function in hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus (PVT...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-020-02062-y
更新日期:2020-11-01 00:00:00