Abstract：
:Controversy still exists over whether there is a magnocellular deficit associated with developmental dyslexia. Here we utilised a magnocellular system-biased phantom contour form discrimination task defined by high temporal frequency contrast reversals to compare contrast sensitivity in a group of children with dyslexia and an age- and nonverbal intelligence-matched control group (9-14 years). Stimuli were either abruptly presented for 4 refresh frames (34 ms), or in two reduced transience conditions had contrast progressively ramped on and off over either 4 frames or 10 frames (86 ms). Children in the dyslexia group showed increased contrast thresholds compared with the control group in all three conditions, and thus strong evidence for a magnocellular deficit. Although the absolute size of the differences in threshold scores between control and dyslexic groups increased dramatically between the abrupt and the 4 and 10 frame ramped onset stimuli, the similar effect size across all tasks, and also the similar range of contrast change at the first frame of stimulus presentation across all tasks between groups suggests that a similar neural mechanism could provide the locus of the apparent magnocellular deficit in children with dyslexia for all tasks tested. These results suggest that threshold discrimination of stimuli with low contrast and high temporal frequencies designed to target the magnocellular system, and has great potential for early screening for children at risk of visually derived reading difficulties.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Laycock R,Crewther DP,Crewther SGdoi
10.1016/j.neuropsychologia.2012.05.012subject
Has Abstractpub_date
2012-07-01 00:00:00pages
2107-13issue
8eissn
0028-3932issn
1873-3514pii
S0028-3932(12)00214-Xjournal_volume
50pub_type
杂志文章相关文献
NEUROPSYCHOLOGIA文献大全abstract：:A number of studies have reported correlations between subjects' asymmetry scores on left and right hemisphere specialized tasks. In this paper we report the results of meta-analyses performed on these correlations. Results showed positive correlations between subjects' asymmetry scores on left and right hemisphere sp...
journal_title：Neuropsychologia
pub_type： 杂志文章,meta分析
doi：10.1016/0028-3932(91)90053-b
更新日期：1991-01-01 00:00:00
abstract：:The ventral temporal cortex (VTC) contains several areas with selective responses to words, numbers, faces, and objects as demonstrated by numerous human and primate imaging and electrophysiological studies. Our recent work using electrocorticography (ECoG) confirmed the presence of face-selective neuronal populations...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2015.08.003
更新日期：2016-03-01 00:00:00
abstract：:Subthalamic deep brain stimulation (STN DBS) is an effective treatment for reducing the motor symptoms of patients with Parkinson's disease (PD), but several side effects have been reported, concerning the processing of emotions. Music has been shown to evoke powerful emotional experiences - not only basic emotions, b...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2018.06.018
更新日期：2018-08-01 00:00:00
abstract：:The present study aimed to determine whether the bradykinesia of Parkinson's disease (PD) patients during the execution of reaching-grasping movements (i) is related to an impaired implementation of movement parameters and (ii) selectively involves the control of reach and/or grasp movements. We compared the kinematic...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2004.06.009
更新日期：2005-01-01 00:00:00
abstract：:People can communicate by using hand actions, e.g., signs. Understanding communicative actions requires that the observer knows that the actor has an intention to communicate and the meanings of the actions. Here, we investigated how this prior knowledge affects processing of observed actions. We used functional MRI t...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2016.01.002
更新日期：2016-01-29 00:00:00
abstract：:Focal retrograde amnesia is an unusual and theoretically challenging form of memory disorder. The case of a 65-year-old woman presenting with focal retrograde amnesia is reported. Following a cardiac arrest and subsequent hypoxia she remained in a coma for 24 h with evidence of epileptiform activity during the early r...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(01)00076-8
更新日期：2002-01-01 00:00:00
abstract：:The variability of episodic memory decline and hippocampal atrophy observed with increasing age may partly be explained by genetic factors. KIBRA (kidney and brain expressed protein) and CLSTN2 (calsyntenin 2) are two candidate genes previously linked to episodic memory performance and volume of the hippocampus, a key...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2015.09.031
更新日期：2015-11-01 00:00:00
abstract：:Patients with Alzheimer's disease (AD) relying predominantly on familiarity for recognition, research has suggested that they may be particularly susceptible to memory illusions driven by conceptual fluency. Using the Jacoby and Whitehouse [Jacoby, L.L., & Whitehouse, K. (1989). An illusion of memory: False recognitio...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2009.04.029
更新日期：2009-10-01 00:00:00
abstract：:Social cognitive neuroscience is a fledgling discipline that has already accrued an impressive body of data, but important questions remain regarding the theoretical constructs and methodological approaches that it utilizes. An overview of the papers in this special issue points to several key issues facing the field....
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/s0028-3932(02)00142-2
更新日期：2003-01-01 00:00:00
abstract：:Executive cognitive functions play a critical role in falls risk—a pressing health care issue in seniors. In particular, intact attentional processing is integral for safe mobility and navigation. However, the specific contribution of impaired visual–spatial attention in falls remains unclear. In this study, we examin...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2013.10.002
更新日期：2013-12-01 00:00:00
abstract：:Visual objects can often be analyzed as hierarchical in structure, composed of local elements that are spatially arranged to form a global shape. The brain mechanisms involved in the analysis of hierarchical figures have been under considerable scrutiny in recent years, and one of the many interesting features that ha...
journal_title：Neuropsychologia
pub_type： 临床试验,杂志文章
doi：10.1016/s0028-3932(99)00080-9
更新日期：2000-01-01 00:00:00
abstract：:Unlike taking, which can be redescribed in non-social and object-directed terms, acts of giving are invariably expressed across languages in a three-argument structure relating agent, patient, and object. Developmental evidence suggests this difference in the syntactic entailment of the patient role to be rooted in a ...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2020.107363
更新日期：2020-03-02 00:00:00
abstract：:The study of the neuroanatomical correlates of category-specific semantic disorders has strongly supported the 'sensory/motor model of semantic knowledge,' which assumes that the cortical areas that have critically contributed to the development of various categories are also implicated in their semantic representatio...
journal_title：Neuropsychologia
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.neuropsychologia.2003.08.006
更新日期：2004-01-01 00:00:00
abstract：:Handwriting impairments in Parkinson's disease (PD) have been associated with micrographia, i.e. diminished letter size. However, dyscoordination of the wrist and fingers may also contribute to handwriting deterioration in PD. To investigate this hypothesis, right-handed PD patients and controls were tested in perform...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2009.04.020
更新日期：2009-10-01 00:00:00
abstract：:Fifty-three patients with unilateral temporal- or right frontal-lobe excision and 12 normal control (NC) subjects read words, sentences and stories presented at slow, normal or fast reading rates. No group differences were noted for the number of errors committed when reading single words or sentences. The left tempor...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/0028-3932(91)90015-z
更新日期：1991-01-01 00:00:00
abstract：:A current controversy exists about the relationship between spatial attention and conscious perception. While some authors propose that these phenomena are intimately related (Bartolomeo, 2008; Chun & Marois, 2002; O'Regan & Noë, 2001; Posner, 1994), others report dissociations between them (Kentridge et al., 1999; Ko...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2011.12.020
更新日期：2012-04-01 00:00:00
abstract：:Because animals and young children cannot be interrogated about their experiences it is difficult to conduct research into their episodic memories. The approach to this issue adopted by Clayton and Dickinson [Clayton, N. S., & Dickinson, A. (1998). Episodic-like memory during cache recovery by scrub jays. Nature, 395,...
journal_title：Neuropsychologia
pub_type： 杂志文章,评审
doi：10.1016/j.neuropsychologia.2008.10.011
更新日期：2009-09-01 00:00:00
abstract：:Heterotopagnosia is the acquired inability of brain-lesioned patients to point at someone else's body parts when prompted. The cognitive basis of this disorder is unclear. It might result from a biological function deficit critical for communication in human beings; alternatively, it could result from the disruption o...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2009.02.016
更新日期：2009-06-01 00:00:00
abstract：:Research investigating the neural correlates of face processing has emphasized differences in neural activity when participants view faces versus other stimulus categories (e.g., houses). Much less is known about the neural mechanisms underlying the discrimination among individual faces. Using a large number of female...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2011.07.030
更新日期：2011-10-01 00:00:00
abstract：:The present study assessed the patterns of cortical gray matter (GM) loss in patients with amnestic mild cognitive impairment (aMCI) with distinct profiles of memory impairment, i.e. aMCI patients failing on both recall and recognition memory vs. aMCI patients showing impaired recall but preserved recognition memory. ...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2007.11.019
更新日期：2008-03-07 00:00:00
abstract：:To assess the role of shape information for unfamiliar face learning, we investigated effects of photorealistic spatial anticaricaturing and caricaturing on later face recognition. We assessed behavioural performance and event-related brain potential (ERP) correlates of recognition, using different images of anticaric...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2012.06.013
更新日期：2012-08-01 00:00:00
abstract：:In vivo occipital asymmetry (OA) measurements have been used to infer functional asymmetries such as language dominance. We investigated the degree of correlation between OA measurements derived by the same rater from different scans of the same subject. We used magnetic resonance (MR) and computerized axial tomograph...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/0028-3932(94)90122-8
更新日期：1994-12-01 00:00:00
abstract：:The left anterior temporal lobe (LATL) is robustly implicated in semantic processing by a growing body of literature. However, these results have emerged from two distinct bodies of work, addressing two different processing levels. On the one hand, the LATL has been characterized as a 'semantic hub׳ that binds feature...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2014.03.001
更新日期：2014-05-01 00:00:00
abstract：:Much of our human mental life looks to involve a seamless unfolding of perception, action and experience: a golden braid in which each element twines intimately with the rest. We see the very world we act in and we act in the world we see. But more than this, visual experience presents us with the world in a way apt f...
journal_title：Neuropsychologia
pub_type： 杂志文章,评审
doi：10.1016/j.neuropsychologia.2008.10.020
更新日期：2009-05-01 00:00:00
abstract：:The detection of social threat is crucial for adaptive behaviour. Previous studies have shown that angry faces capture attention and are processed more efficiently than happy faces. While this anger superiority effect has been found in typical and atypical development, it is unknown whether it exists in individuals wi...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2009.12.006
更新日期：2010-03-01 00:00:00
abstract：:The HERA (Hemispheric Encoding/Retrieval Asymmetry) model captures hemispheric lateralization of prefrontal cortex (PFC) brain activity during memory encoding and retrieval. Reduced HERA has been observed in cross-sectional aging studies, but there is no longitudinal evidence, to our knowledge, on age-related changes ...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2019.107329
更新日期：2020-02-03 00:00:00
abstract：:Human can easily detect other's eyes and gaze from early in life. Such sensitivity is supported by the contrast polarity of human eyes, which have a white sclera contrasting with the darker colored iris (Kobayashi & Kohshima, (1997). Nature, 387, 767-768; Kobayashi & Kohshima, (2001). Journal of Human Evolution, 40, 4...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2013.08.020
更新日期：2013-11-01 00:00:00
abstract：:The issue of where in the human cortex coding of sound location is represented still is a matter of debate. It is unclear whether there are cortical areas that are specifically activated depending on the location of sound. Are identical or distinct cortical areas in one hemisphere involved in processing of sounds from...
journal_title：Neuropsychologia
pub_type： 杂志文章
doi：10.1016/j.neuropsychologia.2005.05.021
更新日期：2006-01-01 00:00:00
abstract：:It is known that reaction time (RT) for the detection of a light target at extrafoveal locations is lengthened by a previous non-informative light cue at the same location. We describe an additional inhibitory effect from cues remote from the target but occurring within the same lateral or altitudinal visual hemifield...
journal_title：Neuropsychologia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0028-3932(89)90172-3
更新日期：1989-01-01 00:00:00
abstract：:This paper aimed to review the limited, but growing literature on prospective memory (PM) following closed head injury (CHI). Search of two commonly used databases yielded studies that could be classified as: self- or other-report of PM deficits; behavioral PM measures in adults with CHI, behavioral PM measures in chi...
journal_title：Neuropsychologia
pub_type： 杂志文章,评审
doi：10.1016/j.neuropsychologia.2011.02.006
更新日期：2011-07-01 00:00:00
