Abstract:
:An account of plasma cholinesterase activity in samples of maternal and cord blood is presented. It is confirmed that plasma exchange markedly reduces the level of activity in maternal blood, and that the level is further reduced during the first 3-4 postnatal days. A particularly marked decrease was found in those cases in which spontaneous mid-trimester abortion occurred. The level of activity in maternal blood (excluding mothers subjected to plasma exchange) at the time of delivery, was higher than that in cord blood in 61% of cases. In 23% of cases the level of activity was appreciably (0.05 units) higher in cord blood, and two-thirds of these cord samples contained the E2+ electrophoretic variant of plasma cholinesterase. The mean levels of activity in maternal and cord blood of Rhesus negative patients were significantly lower than those among Rhesus positive patients but there was no such distinction between Rhesus positive and Rhesus negative males and nonpregnant females. We encountered an incidence of 1:228 abnormal phenotypes in a series of 1593 mothers who underwent Caesarean section under a technique of general anaesthesia which included a suxamethonium infusion. However, probably only two of the seven patients would definitely be sensitive when not pregnant.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Whittaker M,Crawford JS,Lewis Mdoi
10.1111/j.1365-2044.1988.tb05423.xsubject
Has Abstractpub_date
1988-01-01 00:00:00pages
42-5issue
1eissn
0003-2409issn
1365-2044journal_volume
43pub_type
杂志文章相关文献
ANAESTHESIA文献大全abstract::We investigated modifications to the reservoir tube usually used in drawover anaesthetic breathing systems as a method of improving its efficiency and performance. The resulting oxygen concentration was recorded at different oxygen flow rates whilst an artificial lung was being ventilated over a range of minute volume...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2007.05224.x
更新日期:2007-11-01 00:00:00
abstract::Factors that influence the induction of anaesthesia with propofol were investigated in a prospective study of 1000 patients. Pre-operative albumin and urea concentrations correlated with the minimum induction dose of propofol, but less strong correlations were found with haemoglobin, globulin and total protein concent...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1991.tb09320.x
更新日期:1991-01-01 00:00:00
abstract::The optimum time interval for 10 ml boluses of bupivacaine 0.0625% + fentanyl 2 μg.ml-1 as part of a programmed intermittent epidural bolus regimen has been found to be 40 min. This regimen was shown to be effective without the use of supplementary patient-controlled epidural analgesia boluses in 90% of women during t...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/anae.14159
更新日期:2018-04-01 00:00:00
abstract::Directly measured subcutaneous tissue oxygen tension reflects the adequacy of regional tissue oxygenation and influences wound infection and healing. We tested the hypothesis that off-pump coronary artery bypass would increase subcutaneous tissue oxygen tension by minimizing cardiopulmonary bypass-induced systemic inf...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2004.03608.x
更新日期:2004-03-01 00:00:00
abstract::Citrate, as an anticoagulant for continuous renal replacement therapy in critically ill patients, has some potential advantages over heparin, including a prolonged dialysis filter life and reduced risk of bleeding. The key parameter involved in monitoring the adequacy and safety of citrate anticoagulation during conti...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2009.06078.x
更新日期:2009-12-01 00:00:00
abstract::We recorded the survival of 141 patients assessed for radical cystectomy, which included cardiopulmonary exercise testing. The median Kaplan-Meier survival estimates were: 1540 days for the whole cohort; 2200 days after cystectomy scheduled (n = 108); and 843 days without surgery. The mortality hazard remained double ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.15034
更新日期:2020-07-01 00:00:00
abstract::The Portex introducer for the laryngeal mask airway was designed as an aid to successful insertion, acting as an idealised 'artificial hard palate' to guide the tip of the laryngeal mask into the correct position. A number of authors have investigated laryngeal mask insertion by unskilled personnel in certain situatio...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1997.171-az0308.x
更新日期:1997-08-01 00:00:00
abstract::Sixty-one patients received a standardised anaesthetic and were randomly assigned to three groups: tracheal intubation via direct laryngoscopy, tracheal intubation via an intubating laryngeal mask airway with immediate removal of the device, and tracheal intubation via an intubating laryngeal mask airway with delayed ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.2002.02463.x
更新日期:2002-04-01 00:00:00
abstract::The TOF-Guard neuromuscular monitor uses an accelerometer to measure the response to nerve stimulation. In this study, we have compared it to a standard mechanomyographic monitor, the Myograph 2000, for neuromuscular monitoring in 28 subjects. A train-of-four mode of stimulation was used in both cases. The times taken...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1995.tb06097.x
更新日期:1995-08-01 00:00:00
abstract::All senior house officer posts in the Yorkshire Deanery have been assessed against five parameters. Posts in anaesthesia were among the best with excellent consultant support, good exposure to clinical practice and well-structured education and training. Anaesthetic posts were almost unique in satisfying the 'New Deal...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1998.00245.x
更新日期:1998-01-01 00:00:00
abstract::The 50% and 95% effective doses of desflurane for removal of the classic laryngeal mask airway after suction of the upper airway, in anaesthetised spontaneously breathing adult patients, are not known. To determine these, we studied 38 healthy patients, aged between 18 and 44 years. The target desflurane concentration...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2011.06620.x
更新日期:2011-04-01 00:00:00
abstract::A survey was conducted on 100 consecutive patients who underwent spinal anaesthesia in our urology operating theatres. Details of the spinal technique were recorded in the operating theatre. In 25% of patients, more than one attempt at subarachnoid puncture was required and 16% of this group went on to require general...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb03161.x
更新日期:1992-10-01 00:00:00
abstract::Haemophagocytic lymphohistiocytosis secondary to viral infection is an unusual but well recognised cause of bone marrow dysfunction and multiple organ failure in young patients. Two 18 year-old patients were admitted to a tertiary liver unit with features of acute liver failure, cardio-respiratory collapse and pancyto...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2008.05584.x
更新日期:2008-11-01 00:00:00
abstract::The Laryngeal Tube S and the LMA-ProSeal are supraglottic instruments with an improved airway seal and a drainage tube to protect against regurgitation and to facilitate passage of a gastric tube. We compared the feasibility of these two instruments in a randomised, controlled clinical trial. One hundred and sixty pat...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2007.05073.x
更新日期:2007-07-01 00:00:00
abstract::In this prospective randomised study, we compared two techniques for i-gel(™) insertion. One hundred and eighty-one anaesthetised, paralysed adult patients were randomly allocated into one of two groups. In the standard group (n = 91), the i-gel was inserted using the standard technique. In the rotation group (n = 90)...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/anae.12680
更新日期:2014-07-01 00:00:00
abstract::In this, the second of two articles covering specific medical emergencies, we discuss the definitions, epidemiology, pathophysiology, acute and chronic management of pulmonary embolus and acute severe asthma. ...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/anae.12051
更新日期:2013-01-01 00:00:00
abstract:SUMMARY:In view of the controversy over the use of inotropes in free tissue transfer surgery, we assessed the effect of different intra-operative dobutamine infusion rates on blood flow in the anastomosed recipient artery. Twenty patients undergoing head and neck tumour resection and immediate reconstructive surgery wi...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2009.06055.x
更新日期:2009-10-01 00:00:00
abstract::Oxygen and nitrous oxide pipes were cross-connected during the servicing of an anaesthetic machine. This resulted in the delivery of 100% nitrous oxide instead of 100% oxygen at the end of the operation. The patient fully recovered and was discharged on the 13th day. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1983.tb12201.x
更新日期:1983-08-01 00:00:00
abstract::Maternal mortality from aspiration of gastric contents still remains unacceptably high, despite various recommended prophylactic measures. In order to establish which forms of antacid prophylaxis are currently being used, a questionnaire was sent to anaesthetists working in obstetric units in the United Kingdom. Despi...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1986.tb13231.x
更新日期:1986-04-01 00:00:00
abstract::The current international COVID-19 health crisis underlines the importance of adequate and suitable personal protective equipment for clinical staff during acute airway management. This study compares the impacts of standard air-purifying respirators and powered air-purifying respirators during simulated difficult air...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/anae.15102
更新日期:2020-10-01 00:00:00
abstract::We present a patient who suffered two episodes of torsade de pointes ventricular tachycardia during general anaesthesia for abdominal surgery. The first occurred on suctioning of the tracheobronchial tree and the second while anaesthesia was light. Since ST segment elevation was in each case noted before the onset of ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1996.tb12617.x
更新日期:1996-09-01 00:00:00
abstract::Two anaesthetic procedures that did not include nitrous oxide were compared in a randomised study of 50 patients for tympanoplasty and tympanoscopy: propofol given for induction and maintenance, and thiopentone-isoflurane given for induction and maintenance, respectively. Induction in the first group was with a bolus ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1988.tb09083.x
更新日期:1988-03-01 00:00:00
abstract::The circulatory depressant action of papaveretum was demonstrated when the drug was injected accidentally into the radial artery during neuroanaesthesia in the upright (sitting) position. The signs of air embolism were mimicked. The condition reponded promptly to a vasopressor given intravenously. There were no harmfu...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1979.tb06328.x
更新日期:1979-05-01 00:00:00
abstract::Cardiac output (CO) determination based on partial CO(2) rebreathing has recently been introduced into clinical practice. The determination of flow is crucial for exact CO readings and the physical properties of xenon, i.e. high density and viscosity, may influence flow readings. This study compared echocardiography-d...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2004.03897.x
更新日期:2004-11-01 00:00:00
abstract::Eighteen patients with advanced cystic fibrosis complicated by pneumothorax required either pleurectomy or abrasion pleurodesis. Anaesthesia with nitrous oxide and oxygen was combined with controlled ventilation to both lungs, usually through a double lumen endobronchial tube. Spontaneous ventilation was restored at t...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1984.tb06473.x
更新日期:1984-07-01 00:00:00
abstract::The effectiveness of morphine after surgery by patient-controlled analgesia alone or with a concurrent infusion was studied. The infusion did not reduce the dose of self-administered analgesic and patients treated in this way received twice as much drug as those who used patient-controlled analgesia alone. Pain contro...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1989.tb11088.x
更新日期:1989-01-01 00:00:00
abstract::The Triservice anaesthetic apparatus is a draw-over using ambient air as the primary carrier gas. Its modules are a self-inflating bag, a vaporiser, a supplementary oxygen regulator and a ventilator; each is described. The outputs of halothane and trichloroethylene were measured with changes of temperature, continuous...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1981.tb08696.x
更新日期:1981-12-01 00:00:00
abstract::Reports of anaesthetic misadventures were regularly collected in the Anaesthetic Department of a district general hospital, to identify recurring problems. Eighty-one misadventures, none of which had serious outcome, were reported during a 6-month period, in which 8312 anaesthetics were administered. Human error was m...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1981.tb08650.x
更新日期:1981-10-01 00:00:00
abstract::Most of the low-pressure ventilator alarms available have the pressure registration unit connected to the patient circuit by a narrow bore plastic tube. Condensed water in this tube will stop the correct function of the alarm in a few hours if the tube is placed after a heated humidifier. The pressure registration sho...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1979.tb06259.x
更新日期:1979-11-01 00:00:00
abstract::We assessed conditions for insertion of a laryngeal mask airway in 90 unpremedicated adult patients who received either thiopentone 5 mg.kg-1 preceded by 40 mg of topical lignocaine spray to the posterior pharyngeal wall or propofol 2.5 mg.kg-1 alone in a randomised, single-blinded trial. All patients received fentany...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1996.tb07860.x
更新日期:1996-07-01 00:00:00