Inhibition of epidermal growth factor receptor stimulates prolactin expression in primary culture of the mouse pituitary gland.

abstract：:Hypothyroidism during pregnancy and the early postnatal period has severe neurological consequences for the developing offspring. The impact of milder degrees of perturbation of the thyroid axis as encompassed in conditions of subclinical hypothyroidism and hypothyroxinemia, however, has not been established. The pres...

journal_title：Journal of neuroendocrinology

authors： Royland JE,Parker JS,Gilbert ME

更新日期：2008-12-01 00:00:00

abstract：:Doe rabbits nurse once/day for approximately 3 minutes, with circadian periodicity, inside the nest box. The amount of suckling received at each bout regulates this behaviour because reducing the litter size to four kits or less disrupts nursing circadian periodicity and increases suckling bout duration. Additionally,...

journal_title：Journal of neuroendocrinology

authors： Jiménez A,González-Mariscal G

更新日期：2019-09-01 00:00:00

abstract：:In vitro, estrogens stimulate corticotropin-releasing factor (CRF) gene transcription. In ovariectomized (OVX) rats, estrogens have a negative effect on CRF mRNA levels in the hypothalamic paraventricular nucleus. This suggests that the stimulatory influence of estrogens found in vitro may be masked in vivo by an inhi...

journal_title：Journal of neuroendocrinology

authors： Paulmyer-Lacroix O,Héry M,Pugeat M,Grino M

更新日期：1996-07-01 00:00:00

abstract：:The isolation and identification of a prolactin-releasing factor (PRF) from the neuro-intermediate lobe of the pituitary gland has been pursued for over a decade. Using high-pressure liquid chromatography with electrochemical detection (HPLC-ECD) and gas chromatography/mass spectrometry (GC/MS) (R)-salsolinol (SAL) (a...

journal_title：Journal of neuroendocrinology

authors： Tóth BE,Homicskó K,Radnai B,Maruyama W,DeMaria JE,Vecsernyés M,Fekete MI,Fülöp F,Naoi M,Freeman ME,Nagy GM

更新日期：2001-12-01 00:00:00

abstract：:Psychiatric patients suffering from anxiety disorders or endogenous depression exhibit increased activity in their hypothalamo-pituitary-adrenocortical (HPA) axis. Recently, two Wistar rat lines, bred for high (HAB) and low (LAB) anxiety-related behaviour on the elevated plus-maze, were described as a unique psychopat...

journal_title：Journal of neuroendocrinology

authors： Landgraf R,Wigger A,Holsboer F,Neumann ID

更新日期：1999-06-01 00:00:00

abstract：:Maternal hypothyroidism has adverse effects on neural development in the offspring. The present study aimed to investigate whether maternal subclinical hypothyroidism impairs spatial learning in the offspring, as well as the efficacy and optimal time of levothyroxine (L-T(4)) treatment in pregnancy. Female adult Wista...

journal_title：Journal of neuroendocrinology

authors： Wang S,Teng W,Gao Y,Fan C,Zhang H,Shan Z

更新日期：2012-05-01 00:00:00

abstract：:In seasonal mammals living in temperate zones, photoperiod regulates prolactin secretion, such that prolactin plasma concentrations peak during the summer months and are lowest during the winter. In sheep, a short-day breeder, circulating prolactin has important modulatory effects on the reproductive system via inhibi...

journal_title：Journal of neuroendocrinology

authors： Christian HC,Imirtziadis L,Tortonese D

更新日期：2015-04-01 00:00:00

abstract：:The authors have identified two types of hippocampal cDNAs for the rat mineralocorticoid receptor (rMR) which are identical in the protein coding domain but differ in their 5'-untranslated sequences. One of these clones encodes a novel type of rMR cDNA with a high homology to a previously described human MR cDNA isola...

journal_title：Journal of neuroendocrinology

authors： Castrén M,Damm K

更新日期：1993-08-01 00:00:00

abstract：:Subclinical hypothyroidism (SCH) is characterized by mild elevation of thyroid stimulating hormone (TSH) (range 5-10 μIU/ml) and normal free triiodothyronine (FT3) and free thyroxine (FT4). The cognitive function impairment is well known in thyroid disorders such as hypothyroidism and hyperthyroidism, but little is kn...

journal_title：Journal of neuroendocrinology

authors： Kumar M,Modi S,Rana P,Kumar P,Kanwar R,Sekhri T,D'souza M,Khushu S

更新日期：2018-03-05 00:00:00

abstract：:Rapid nonclassical effects of 17β-oestradiol (E2 ) on intracellular signalling have been identified in the basal forebrain, although the extent to which these actions may be different in males and females is unknown. Previous work has shown that E2 rapidly phosphorylates cAMP responsive element binding protein (CREB) ...

journal_title：Journal of neuroendocrinology

authors： Kim S,Barad Z,Cheong RY,Ábrahám IM

更新日期：2020-01-01 00:00:00

abstract：:Female Long-Evans rats exhibit stable individual differences in maternal behaviours such as pup licking/grooming and arched-back nursing posture (LG-ABN). These variations in maternal behaviour are accompanied by differences in lactation-induced increases in oxytocin receptor levels in brain regions known to mediate t...

journal_title：Journal of neuroendocrinology

authors： Francis DD,Champagne FC,Meaney MJ

更新日期：2000-12-01 00:00:00

abstract：:Aldosterone has been reported to impair the baroreflex response in animal models. The present study aimed to investigate the acute effects of aldosterone on the autonomic nervous system and the baroreflex control of muscle sympathetic nerve activity (MSNA) and heart rate in healthy humans. Nine healthy subjects were e...

journal_title：Journal of neuroendocrinology

authors： Heindl S,Holzschneider J,Hinz A,Sayk F,Fehm HL,Dodt C

更新日期：2006-02-01 00:00:00

abstract：:Estrogen is known to play an important role in regulating reproductive function in female rats through actions exerted at the preoptic area, a part of the brain that is markedly sexually dimorphic and which contains abundant estrogen receptors. A critical question to our understanding of estrogen's action on the brain...

journal_title：Journal of neuroendocrinology

authors： Watson RE Jr,Hutchinson RK,Langub MC Jr,Landis JW,Seksaria S,Rainey DM,Keil LC

更新日期：1994-02-01 00:00:00

abstract：:Recent findings relate obesity to inflammation in key hypothalamic areas for body weight control. Hypothalamic inflammation has also been related to oxidative stress. Palmitic acid (PA) is the most abundant free fatty acid found in food, and in vitro studies indicate that it triggers a pro-inflammatory response in the...

journal_title：Journal of neuroendocrinology

authors： Ramírez D,Saba J,Turati J,Carniglia L,Imsen M,Mohn C,Scimonelli T,Durand D,Caruso C,Lasaga M

更新日期：2019-02-01 00:00:00

abstract：:The adipose tissue-derived hormone leptin may be a primary mediator linking nutritional status and reproduction. The present study used the leptin-resistant obese female Zucker rat to investigate whether leptin signalling is required for normal pulsatile luteinizing hormone (LH) secretion and/or generation of the LH s...

journal_title：Journal of neuroendocrinology

authors： Todd BJ,Ladyman SR,Grattan DR

更新日期：2003-01-01 00:00:00

abstract：:Impaired cognitive function and enhanced activity of the hypothalamic-pituitary-adrenocortical system are among the cardinal symptoms of major depression in humans that resolve after successful antidepressant treatment. We used a transgenic mouse model expressing antisense RNA complementary to that of glucocorticoid r...

journal_title：Journal of neuroendocrinology

authors： Montkowski A,Barden N,Wotjak C,Stec I,Ganster J,Meaney M,Engelmann M,Reul JM,Landgraf R,Holsboer F

更新日期：1995-11-01 00:00:00

abstract：:Growth hormone (GH) is known to regulate peripheral components of the hypothalamo-pituitary gonadal (HPG) axis, but it remains unclear whether GH exerts a significant influence on the activity of the hypothalamo-pituitary components of the HPG axis. In this study, we investigated the development of HPG axis function i...

journal_title：Journal of neuroendocrinology

authors： Davies JS,Thompson NM,Christian HC,Pinilla L,Ebling FJ,Tena-Sempere M,Wells T

更新日期：2006-10-01 00:00:00

abstract：:Metabotropic glutamate receptor subtype 7 (mGluR7) is one of the group III mGluRs, which are negatively coupled to adenylate cyclase via Gi/Go proteins and localised to presynaptic active zones of the mammalian central nervous system. We previously reported that mGluR7 is essential for intermale aggression and amygdal...

journal_title：Journal of neuroendocrinology

authors： Masugi-Tokita M,Yoshida T,Kageyama S,Kawata M,Kawauchi A

更新日期：2018-03-01 00:00:00

abstract：:The growth hormone (GH) axis is sensitive to alteration in body weight and there is evidence that central noradrenergic systems regulate neurones that produce growth hormone-releasing hormone (GHRH) and somatostatin (SRIF). This study reports semiquantitative estimates of the noradrenergic input to neuroendocrine GHRH...

journal_title：Journal of neuroendocrinology

authors： Iqbal J,Manley TR,Yue Q,Namavar MR,Clarke IJ

更新日期：2005-06-01 00:00:00

abstract：:Neuropeptide Y (NPY) is found in autonomic neurones and participates in regulation of autonomic functions. To investigate the role of NPY in the stress response in normo- and hypertensive rats, activation of brainstem and arcuate nucleus (ARC) NPY neurones and levels of NPY mRNA in the ARC were measured in response to...

journal_title：Journal of neuroendocrinology

authors： Krukoff TL,MacTavish D,Jhamandas JH

更新日期：1999-09-01 00:00:00

abstract：:Humans have engineered a dietary environment that has driven the global prevalence of obesity and several other chronic metabolic diseases to pandemic levels. To prevent or treat obesity and associated comorbidities, it is crucial that we understand how our dietary environment, especially in combination with a sedenta...

journal_title：Journal of neuroendocrinology

authors： Slomp M,Belegri E,Blancas-Velazquez AS,Diepenbroek C,Eggels L,Gumbs MCR,Joshi A,Koekkoek LL,Lamuadni K,Ugur M,Unmehopa UA,la Fleur SE,Mul JD

更新日期：2019-05-01 00:00:00

abstract：:Most mammals living at temperate latitudes exhibit marked seasonal variations in reproduction. In long-lived species, it is assumed that timely physiological alternations between a breeding season and a period of sexual rest depend upon the ability of day length (photoperiod) to synchronise an endogenous timing mechan...

journal_title：Journal of neuroendocrinology

authors： Dardente H

更新日期：2012-02-01 00:00:00

abstract：:Metabolic health founds on a homeostatic balance that has to integrate the daily changes of rest/activity and feeding/fasting cycles. A network of endogenous 24-hour circadian clocks helps to anticipate daily recurring events and adjust physiology and behavioural functions accordingly. Circadian clocks are self-sustai...

journal_title：Journal of neuroendocrinology

authors： Kolbe I,Brehm N,Oster H

更新日期：2019-05-01 00:00:00

abstract：:The neural and neurochemical substrates regulating reproduction in birds remain vaguely defined. The findings that electrical stimulation in the medial preoptic area (ES/MPOA) or intracerebroventricular infusion of dopamine (DA) stimulated luteinising hormone (LH) and prolactin (PRL) release in female turkeys, led to ...

journal_title：Journal of neuroendocrinology

authors： Al-Zailaie KA,Kang SW,Youngren OM,Thayananuphat A,Bakken T,Chaiseha Y,Millam JR,Proudman JA,El Halawani ME

更新日期：2006-07-01 00:00:00

abstract：:Deviant forms of aggressiveness have been associated with low plasma glucocorticoid concentrations in humans. Here, we report data on the development of aggressive behaviour in rats in which glucocorticoid secretion was inhibited by adrenalectomy. Such rats were compared with both sham operated rats and adrenalectomiz...

journal_title：Journal of neuroendocrinology

authors： Haller J,van de Schraaf J,Kruk MR

更新日期：2001-01-01 00:00:00

abstract：:The seasonal pattern of breeding in sheep offers an opportunity to examine plasticity of neuronal inputs to gonadotropin-releasing hormone (GnRH) neurones. We used conventional fluorescence microscopy and confocal microscopy to compare the extent of input to GnRH neurones from various neuropeptide/neurotransmitter sys...

journal_title：Journal of neuroendocrinology

authors： Pompolo S,Pereira A,Kaneko T,Clarke IJ

更新日期：2003-05-01 00:00:00

abstract：:Acute illness in mice profoundly affects thyroid hormone metabolism in the hypothalamus and pituitary gland. It remains unknown whether the thyroid hormone receptor (TR)-β is involved in these changes. In the present study, we investigated central thyroid hormone metabolism during lipopolysaccharide (LPS)-induced illn...

journal_title：Journal of neuroendocrinology

authors： Boelen A,Kwakkel J,Chassande O,Fliers E

更新日期：2009-05-01 00:00:00

abstract：:Both natural oestrogens and progesterone influence synaptic plasticity and neurogenesis within the female hippocampus. However, less is known of the impact of synthetic hormones on hippocampal structure and function. There is some evidence that the administration of the synthetic progestin, medroxyprogesterone acetate...

journal_title：Journal of neuroendocrinology

authors： Chan M,Chow C,Hamson DK,Lieblich SE,Galea LA

更新日期：2014-06-01 00:00:00

abstract：:We have recently shown that impaired gastric motility observed in acute restraint stress was restored following repeated restraint stress in mice. Repeated restraint stress up-regulates oxytocin mRNA expression and down-regulates corticotrophin-releasing factor (CRF) mRNA expression at the hypothalamus. Oxytocin knock...

journal_title：Journal of neuroendocrinology

authors： Babygirija R,Zheng J,Bülbül M,Cerjak D,Ludwig K,Takahashi T

更新日期：2010-11-01 00:00:00

abstract：:Carbetocin, a long-acting oxytocin analogue, has been reported to elicit interesting and peculiar behavioural effects. The present study investigated the molecular pharmacology of carbetocin, aiming to better understand the molecular basis of its action in the brain. Using bioluminescence resonance energy transfer bio...

journal_title：Journal of neuroendocrinology

authors： Passoni I,Leonzino M,Gigliucci V,Chini B,Busnelli M

更新日期：2016-04-01 00:00:00