Blood levels of PCDDs, PCDFs, and coplanar PCBs in Yusho mothers and their descendants: association with fetal Yusho disease.

Abstract:

:Maternal exposure to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) may result in adverse health effects in their children. In Japan in 1968, an accidental human exposure to rice oil contaminated with PCDDs, PCDFs, and PCBs, led to the development of Yusho disease. Yusho mothers delivered descendants with low birth weights and hyperpigmented skin and mucosa, which are characteristic of fetal Yusho disease (FYD). The Yusho cohort was used to evaluate the effect of maternal exposure to PCDDs, PCDFs, and PCBs on the development of FYD. Blood samples, obtained from 64 Yusho mothers (117 descendants: 10 with FYD and 107 without FYD), were analyzed for congeners of seven PCDDs, 10 PCDFs, and four coplanar PCBs. We investigated the association between the maternal estimated blood levels of dioxins at delivery and the risk of fetal Yusho disease. We also studied the differences in dioxin blood levels in 24 mother-descendant pairs (5 with FYD and 19 without FYD). The estimated levels of total PCDD TEQ, total PCDF TEQ, total coplanar PCB TEQ, and total TEQ in the maternal blood at delivery were associated with significantly increased risk of FYD. The odds ratios, which present the risk of FYD for a 10-fold increase in blood dioxin, were largest for 1,2,3,6,7,8-HexaCDD (odds ratio=28.6, 95% confidence interval=1.67-489.9, p=0.02). The levels of 1,2,3,6,7,8-HexaCDD in both the Yusho mothers and their descendants with FYD were higher than the levels in those without FYD. These findings suggest that 1,2,3,6,7,8-HexaCDD is the most important causative congener for the development of FYD.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Tsukimori K,Uchi H,Tokunaga S,Yasukawa F,Chiba T,Kajiwara J,Hirata T,Furue M

doi

10.1016/j.chemosphere.2012.08.024

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

1581-8

issue

5

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(12)01062-4

journal_volume

90

pub_type

杂志文章
  • Influence of electrical fields (AC and DC) on phytoremediation of metal polluted soils with rapeseed (Brassica napus) and tobacco (Nicotiana tabacum).

    abstract::The combined use of electrokinetic remediation and phytoremediation to decontaminate soil polluted with heavy metals has been demonstrated in a laboratory-scale experiment. The plants species selected were rapeseed and tobacco. Three kinds of soil were used: un-contaminated soil from forest area (S1), artificially con...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2010.12.052

    authors: Bi R,Schlaak M,Siefert E,Lord R,Connolly H

    更新日期:2011-04-01 00:00:00

  • Perfluorooctane sulfonate in surface soils: Effects on reproduction in the collembolan, Folsomia candida, and the oribatid mite, Oppia nitens.

    abstract::Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant, which has been detected at significant concentrations in soils at sites used for fire-fighting training operations. Recent ecotoxicological research has mainly focused on earthworms to assess the toxicity of PFOS in soil. However, the inclusion of oth...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2018.06.020

    authors: Princz J,Jatar M,Lemieux H,Scroggins R

    更新日期:2018-10-01 00:00:00

  • A new extraction procedure to abate the burden of non-extractable antibiotic residues in manure.

    abstract::Through agricultural soil fertilization using organic manure, antibiotic residues can accumulate in the environment. In order to assess the risks of environmental pollution by veterinary drugs, monitoring of manure for antibiotic residues is necessary. As manure is a complex matrix, extraction of antibiotics proved to...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2019.02.166

    authors: Jansen LJM,van de Schans MGM,de Boer D,Bongers IEA,Schmitt H,Hoeksma P,Berendsen BJA

    更新日期:2019-06-01 00:00:00

  • Determination and estimation of water solubilities and octanol/water partition coefficients for derivates of benzanilides.

    abstract::A shake-flask method was used to determine the water solubilities (Sw) and the octanol/water partition coefficients(Kow) of 14 derivates of benzanilides. The results showed that the octanol/water partition coefficients were correlated (r=-0.93) with Sw. The linear solvation energy relationship(LSER) and molecular conn...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/s0045-6535(98)00132-5

    authors: Dai J,Jin L,Wang L,Zhang Z

    更新日期:1998-10-01 00:00:00

  • Effects of atmospheric ageing under different temperatures on surface properties of sludge-derived biochar and metal/metalloid stabilization.

    abstract::Ageing is a common phenomenon during biochar storage and its soil application. In this study, we exposed sludge-derived biochar (SDBC) in the air under 4 °C, 22 °C, and 45 °C for 30-120 d to imitate the ageing process after SDBC production. The aged SDBC was characterized and its sorption capacities for Pb(II), Cr(V) ...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2017.05.175

    authors: Wang H,Feng M,Zhou F,Huang X,Tsang DCW,Zhang W

    更新日期:2017-10-01 00:00:00

  • Leaching behaviour of wood treated with creosote.

    abstract::The results of a laboratory investigation on the leaching behaviour of wood treated with creosote and of untreated wood are reported. A special leaching test derived from the German standard method DEV S4 test (DIN 38414) has been developed. Samples were leached in deionized water, in a solution buffered at pH 4.7 and...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/s0045-6535(00)00071-0

    authors: Becker L,Matuschek G,Lenoir D,Kettrup A

    更新日期:2001-01-01 00:00:00

  • PAH contaminated soil remediation by reusing an aqueous solution of cyclodextrins.

    abstract::We studied the possibility to re-use an aqueous solution of methyl-beta-cyclodextrin (bpmCD) in order to decontaminate a soil polluted by phenanthrene and pyrene. The loss of bpmCD in the soil was insignificant. In order to eliminate polycylic aromatic hydrocarbons (PAHs) from the contaminated aqueous solution, on one...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2009.01.072

    authors: Petitgirard A,Djehiche M,Persello J,Fievet P,Fatin-Rouge N

    更新日期:2009-05-01 00:00:00

  • Solar light induced transformation mechanism of allyl alcohol to monocarbonyl and dicarbonyl compounds on different TiO2: A combined experimental and theoretical investigation.

    abstract::Enols are an important group of photochemical precursors of atmospheric carbonyl compounds. However, the transformation mechanism is not fully understood. In this study, the photo-induced transformation of a typical enol, allyl alcohol, to carbonyl compounds on TiO2 (P25) and aluminum reduced TiO2 (P25, rutile and ana...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2019.05.219

    authors: Li J,Chen J,Ji Y,Wang J,Li G,An T

    更新日期:2019-10-01 00:00:00

  • Butyltins in water, biofilm, animals and sediments of the west coast of India.

    abstract::Biofilm, fish, oyster, mussel, clam, surface seawater, suspended particulate matter (SPM), and sediment samples were collected from marine and/or estuarine waters of the west coast of India. These samples were analysed for butyltin derivatives such as dibutyltin (DBT) and tributyltin (TBT). The concentrations DBT plus...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2004.06.037

    authors: Bhosle NB,Garg A,Jadhav S,Harjee R,Sawant SS,Venkat K,Anil AC

    更新日期:2004-11-01 00:00:00

  • Screening study of four environmentally relevant microplastic pollutants: Uptake and effects on Daphnia magna and Artemia franciscana.

    abstract::This study investigated four different environmentally relevant microplastic (MP) pollutants which were derived from two facial cleansers, a plastic bag and polyethylene textile fleece. The mean size range of the particles (according to number distribution) was 20-250 μm when measured as a powder and 0.02-200 μm in su...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2018.05.172

    authors: Kokalj AJ,Kunej U,Skalar T

    更新日期:2018-10-01 00:00:00

  • Study of transportation and distribution of PCBs using an ecologically simulated growth chamber.

    abstract::This study was designed to investigate the transportation, distribution, and bioaccumulation of PCBs in various environmental media and compartments using an ecologically simulated growth chamber. Spatial and temporal trends of PCBs in the growth chamber were discussed. The release of PCB congeners in soil was affecte...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2005.11.065

    authors: Lin YJ,Liu HC,Hseu ZY,Wu WJ

    更新日期:2006-07-01 00:00:00

  • Estimation of dioxin risk to Japanese from the past to the future.

    abstract::The transport processes of seventeen 2,3,7,8-chlorinated congeners of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) from their major sources to humans were modeled to estimate the time course, from the past to the future, of the human health risk to the Japanese population. The comparison between measu...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/S0045-6535(03)00011-0

    authors: Yoshida K,Nakanishi J

    更新日期:2003-10-01 00:00:00

  • Mineralization of organic micropollutants (homologous alcohols and phenols) in water by vacuum-UV-oxidation (H2O-VUV) with an incoherent xenon-excimer lamp at 172 nm.

    abstract::Twenty different organic micropollutants (for example C1-C8 homologous alcohols and some phenols) in aqueous solution were subjected to vacuum-UV-oxidation (H2O-VUV) within a xenon-excimer flow-through photoreactor. The incoherent xenon-excimer lamp used exhibited an emission maximum at 172 nm. At this wavelength wate...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/s0045-6535(99)00222-2

    authors: Oppenländer T,Gliese S

    更新日期:2000-01-01 00:00:00

  • Concentrations of polybrominated diphenyl ethers, organochlorine compounds and nitro musks in mother's milk from Germany (Bavaria).

    abstract::The aim of this study was to determine a new spectrum of substances that will be selected for future breast milk monitoring in Bavaria, Germany. Up to now, the analysis of breast milk in Bavaria was limited to selected organochlorine pesticides (OCP) and polychlorinated biphenyls (PCB). Information on background level...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2008.01.053

    authors: Raab U,Preiss U,Albrecht M,Shahin N,Parlar H,Fromme H

    更新日期:2008-05-01 00:00:00

  • Adsorption of microcystins by carbon nanotubes.

    abstract::The production of cyanobacterial toxins microcystins (MCs) by cyanobacterial bloom which may promote the growth of tumor in human liver is a growing environmental problem worldwide. In this paper, the adsorption of MC-RR and LR, which were extracted from cyanobacterial cells in Dianchi Lake in China, by carbon nanotub...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2005.03.075

    authors: Yan H,Gong A,He H,Zhou J,Wei Y,Lv L

    更新日期:2006-01-01 00:00:00

  • Prevalence and sources of polychlorinated biphenyls in the atmospheric environment of Lake Victoria, East Africa.

    abstract::The large surface area of Lake Victoria (about 68,800 km2) makes it vulnerable to high atmospheric deposition of chemical pollutants. We present measurements of polychlorinated biphenyls (PCBs) from the lake's atmospheric environment. High volume air (24 h) samples were collected within the northern Lake Victoria wate...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2017.11.041

    authors: Arinaitwe K,Muir DCG,Kiremire BT,Fellin P,Li H,Teixeira C,Mubiru DN

    更新日期:2018-02-01 00:00:00

  • Synthesis of polyaluminium chloride/papermaking sludge-based organic polymer composites for removal of disperse yellow and reactive blue by flocculation.

    abstract::In this study, a series of polyaluminium chloride/papermaking sludge-based organic polymer (PAC-PSBF) composites with different PAC basicity and PAC/PSBF mass ratios were prepared from papermaking sludge. The basic properties of the aforementioned composites were characterized, and their flocculation efficiencies were...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2019.05.138

    authors: Guo K,Gao B,Tian X,Yue Q,Zhang P,Shen X,Xu X

    更新日期:2019-09-01 00:00:00

  • Occurrence of perchlorate in drinking water, groundwater, surface water and human saliva from India.

    abstract::Perchlorate (ClO(4)(-)), which is used as an oxidizer in jet and rocket fuels, pyrotechnic devices and explosives, is a widespread contaminant in surface waters and groundwater of many countries. Perchlorate is known to affect thyroid function. Despite the compound's widespread occurrence and potential health effects,...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2009.02.054

    authors: Kannan K,Praamsma ML,Oldi JF,Kunisue T,Sinha RK

    更新日期:2009-06-01 00:00:00

  • Facile synthesis of manganese oxide-embedded mesoporous carbons and their adsorbability towards methylene blue.

    abstract::Herein, a facile strategy to fabricate the novel manganese oxide-imprinted mesoporous carbons (MOPCx, x presents for pyrolysis temperature) was described via the direct pyrolysis of Mn2(BDC)2(DMF)2 (BDC = 1,4-benzenedicarboxylate, DMF = N,N-dimethylformamide) as a self-sacrificed template at various temperatures (x = ...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2019.04.079

    authors: Van Tran T,Nguyen DTC,Le HTN,Duong CD,Bach LG,Nguyen HT,Nguyen TD

    更新日期:2019-07-01 00:00:00

  • Solar photocatalytic degradation of naphthenic acids in oil sands process-affected water.

    abstract::Bitumen mining in the Canadian oil sands creates large volumes of oil sands process-affected water (OSPW), the toxicity of which is due in part to naphthenic acids (NAs) and other acid extractable organics (AEO). The objective of this work was to evaluate the potential of solar photocatalysis over TiO2 to remove AEO f...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2015.10.073

    authors: Leshuk T,Wong T,Linley S,Peru KM,Headley JV,Gu F

    更新日期:2016-02-01 00:00:00

  • Denitrification of synthetic concentrated nitrate wastes by aerobic granular sludge under anoxic conditions.

    abstract::The aim of the present work was to determine the denitrification potential of aerobic granular sludge for concentrated nitrate wastes. We cultivated mixed microbial granules in a sequencing batch reactor operated at a superficial air velocity of 0.8 cm s(-1). The denitrification experiments were performed under anoxic...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2011.06.077

    authors: Nancharaiah YV,Venugopalan VP

    更新日期:2011-10-01 00:00:00

  • Dissipation kinetics and residues of florasulam and tribenuron-methyl in wheat ecosystem.

    abstract::The dissipation kinetics and residual levels of florasulam and tribenuron-methyl in wheat field ecosystem were determined using a quick, easy, cheap, efficient, rugged and safe method (QuEChERS) with rapid resolution liquid chromatography tandem mass spectrometry (RRLC-MS/MS). The average recoveries of florasulam and ...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2014.09.016

    authors: Dong B,Qian W,Hu J

    更新日期:2015-02-01 00:00:00

  • Inactivation and injury assessment of Escherichia coli during solar and photocatalytic disinfection in LDPE bags.

    abstract::Solar disinfection (SODIS) of Escherichia coli suspensions in low-density polyethylene bag reactors was investigated as a low-cost disinfection method suitable for application in developing countries. The efficiency of a range of SODIS reactor configurations was examined (single skin (SS), double skin, black-backed si...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2011.09.006

    authors: Dunlop PS,Ciavola M,Rizzo L,Byrne JA

    更新日期:2011-11-01 00:00:00

  • Removal of NOM from drinking water: Fenton's and photo-Fenton's processes.

    abstract::The control of disinfection by-products during water treatment is primarily undertaken by reducing the levels of precursor species prior to chlorination. As many waters contain natural organic matter at levels of up to 15 mgl(-1) there is a need for a range of control methods to support conventional coagulation. Two s...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2003.08.040

    authors: Murray CA,Parsons SA

    更新日期:2004-02-01 00:00:00

  • Ultrafast removal of arsenic using solid solution of aero-gel based Ce1-XTixO2-Y oxide nanoparticles.

    abstract::An aero-gel based solid solution of titanium and cerium oxide nanoparticles have been used for the first time for ultra fast and trace level removal of arsenic from water. The interconnected long range ordered mesoporous structure was observed from TEM analysis which has been verified as an essential facet for the fas...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2018.11.003

    authors: Mishra PK,Rai PK

    更新日期:2019-02-01 00:00:00

  • Arsenic behavior in newly drilled wells.

    abstract::In the present paper, inorganic arsenic species and chemical parameters in groundwater were determined to investigate the factors related to the distribution of arsenic species and their dissolution from rock into groundwater. For the study, groundwater and core samples were taken at different depths of two newly dril...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/S0045-6535(03)00244-3

    authors: Kim MJ,Nriagu J,Haack S

    更新日期:2003-07-01 00:00:00

  • Experimental Zn(II) retention in a sandy loam soil by very small columns.

    abstract::The use of column experiments, usually performed to better approximate field conditions, may provide information that is not available from batch experiments. In such experiments heavy metals are often adsorbed until saturation followed by desorption experiments. When the affinity of the metal to soil is high, the ret...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2006.06.047

    authors: Miretzky P,Muñoz C,Carrillo-Chávez A

    更新日期:2006-12-01 00:00:00

  • Adsorptive removal of an acid dye by lignocellulosic waste biomass activated carbon: equilibrium and kinetic studies.

    abstract::Chemically prepared activated carbon material derived from palm flower was used as adsorbent for removal of Amido Black dye in aqueous solution. Batch adsorption studies were performed for the removal of Amido Black 10B (AB10B), a di-azo acid dye from aqueous solutions by varying the parameters like initial solution p...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2010.11.080

    authors: Nethaji S,Sivasamy A

    更新日期:2011-03-01 00:00:00

  • Seasonality in polybrominated diphenyl ether concentrations in the atmosphere of the Yangtze River Delta, China.

    abstract::Polybrominated diphenyl ether (PBDE) concentrations in the atmosphere in rapidly developing parts of China have been studied little. In this study, polyurethane foam disk passive air samplers were used to comprehensively investigate PBDE concentrations in the atmosphere of the Yangtze River Delta in different seasons ...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2016.01.001

    authors: Zhang L,Dong L,Huang Y,Shi S,Yang W,Zhou L

    更新日期:2016-05-01 00:00:00

  • Bioavailability and detoxification of cationics: I. Algal toxicity of alkyltrimethyl ammonium salts in the presence of suspended sediment and humic acid.

    abstract::We investigated the role of sorption in reducing bioavailability and consequently the measured toxicity of monoalkyl trimethyl ammonium salts (MAQ) under environmental conditions. The observed toxicity of MAQ in the presence of various types of sorbents was tested on algae. Decreased toxicity was found in the presence...

    journal_title:Chemosphere

    pub_type: 杂志文章

    doi:10.1016/j.chemosphere.2008.12.047

    authors: van Wijk D,Gyimesi-van den Bos M,Garttener-Arends I,Geurts M,Kamstra J,Thomas P

    更新日期:2009-04-01 00:00:00