Abstract:
PURPOSE:To determine the diagnostic performance of diffusion-weighted (DW) imaging for the prediction of treatment failure in primary head and neck squamous cell carcinoma (HNSCC). MATERIALS AND METHODS:The study was approved by the local institutional ethics committee and conducted with informed written consent in patients with primary HNSCC treated with radiation therapy and chemotherapy. DW imaging of the primary tumor was performed before treatment in 37 patients and was repeated within 2 weeks of treatment in 30 patients. Histograms of apparent diffusion coefficients (ADCs) were analyzed, and mean ADC, kurtosis, skewness, and their respective percentage change were correlated for local failure and local control at 2 years by using the Student t test. Univariate and multivariate analyses of the ADC parameters, T stage, and tumor volume were performed by using logistic regression for prediction of local failure. RESULTS:Local failure occurred in 16 of 37 (43%) patients and local control occurred in 21 of 37 (57%) patients. Pretreatment ADC parameters showed no correlation with local failure. There was significant intratreatment increase in mean ADC and a decrease in skewness and kurtosis (P < .001, P < .001, P = .024, respectively) for the whole group of patients when compared with those before treatment. During treatment, primary tumors showed a significantly lower increase in percentage change of mean ADC, higher skewness, and higher kurtosis for local failure than for local control (P = .016, .015, and .040, respectively). These ADC parameters also were significant for predicting local failure with use of univariate but not multivariate analysis. CONCLUSION:Early intratreatment DW imaging has the potential to allow prediction of treatment response at the primary site in patients with HNSCC.
journal_name
Radiologyjournal_title
Radiologyauthors
King AD,Chow KK,Yu KH,Mo FK,Yeung DK,Yuan J,Bhatia KS,Vlantis AC,Ahuja ATdoi
10.1148/radiol.12120167subject
Has Abstractpub_date
2013-02-01 00:00:00pages
531-8issue
2eissn
0033-8419issn
1527-1315pii
radiol.12120167journal_volume
266pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::To evaluate the ability of ultrasonography (US) to determine venous tumor extension, we studied 120 consecutive patients with renal neoplasms. The incidence of renal vein involvement in this group was 18%; caval tumor extension occurred in 11% of the patients. Real-time US clearly visualized the entire retrohepatic in...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.156.2.3892580
更新日期:1985-08-01 00:00:00
abstract::This paper reviews some of the fundamental technical and diagnostic problems in clinical uroradiology, such as (a) the reason for the obstructive nephrogram; (b) why high-dose urography gives better studies than low-dose; (c) why the Trueta phenomenon has not been demonstrated in man; (d) the case for an intrarenal ar...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/116.2.259
更新日期:1975-08-01 00:00:00
abstract::A patent umbilical vein is a sonographic sign of portal hypertension. The specificity of the sign is not known. In a review of 12 patients with sonographically demonstrated patency of the umbilical vein, we found two patients in whom no clinical evidence existed to suggest the presence of portal hypertension. In six o...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.145.2.7134450
更新日期:1982-11-01 00:00:00
abstract:PURPOSE:To compare the association between neurodevelopmental outcome in neonates with hypoxic-ischemic encephalopathy following perinatal asphyxia and (a) apparent diffusion coefficients (ADCs) in the thalamus and basal ganglia at diffusion-weighted (DW) magnetic resonance (MR) imaging and (b) hydrogen 1 (¹H) MR spect...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11110213
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:To evaluate the use, final outcome, and positive biopsy rate of American College of Radiology ultrasonographic (US) Breast Imaging Reporting and Data System (BI-RADS) categories 3, 4, and 5 recommended for breast masses. MATERIALS AND METHODS:At US, consecutive masses, palpable and nonpalpable, categorized as ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2483071786
更新日期:2008-09-01 00:00:00
abstract::Endoleaks were detected with helical computed tomographic (CT) angiography in five patients after placement of an aortobiliac stent-graft. The leaks were subsequently evaluated with duplex ultrasonography (US) and, in four patients, with conventional aortography as well. CT angiography revealed a total of seven endole...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2253011806
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:To retrospectively evaluate the long-term results of radiofrequency (RF) ablation combined with chemoembolization (combination therapy) as compared with hepatectomy for the treatment of early-stage hepatocellular carcinoma (HCC). MATERIALS AND METHODS:The study was approved by the institutional review board, a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2471070818
更新日期:2008-04-01 00:00:00
abstract::The findings at magnetic resonance (MR) imaging in a group of 36 pathologically verified supratentorial gliomas were analyzed and compared with the biopsy diagnoses (a) to determine whether MR imaging could be used to classify astrocytic-series tumors into a three-tiered system of low-grade astrocytoma, anaplastic ast...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.174.2.2153310
更新日期:1990-02-01 00:00:00
abstract::Gray-scale ultrasonography of the thyroid was performed in 33 patients, utilizing a commercially available scanning unit and an aqueous gel coupling medium. Solid and cystic lesions could readily be differentiated, but it was impossible to tell benign lesions from malignant tumors. The ultrasound appearance of thyroid...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/120.2.381
更新日期:1976-08-01 00:00:00
abstract::Dose distributions in electron-beam arc therapy were investigated using the electron beam from a Brown Boveri 45 MeV betatron. This variable isocenter machine is equipped with an angular speed control device that synchronizes the radiation dose rate with the rotation speed about the isocenter. An Alderson Rando phanto...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/133.2.483
更新日期:1979-11-01 00:00:00
abstract::A variation in ossification of the acromial process of the scapula is described. Postmortem radiographs, obtained in 78 infants who died of sudden infant death syndrome, showed an ossific opacity adjacent to the acromial process in 10 infants (13%). This finding was noted bilaterally in six patients and unilaterally i...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.180.1.2052690
更新日期:1991-07-01 00:00:00
abstract:PURPOSE:To compare prenatal ultrasonography (US) and magnetic resonance (MR) imaging for the diagnosis of fetal anomalies. MATERIALS AND METHODS:Images of 27 fetuses (28 diagnostic cases) with anomalies diagnosed at US were evaluated; in these fetuses, prenatal MR imaging was performed within 15 days of US. Prenatal U...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2322030504
更新日期:2004-08-01 00:00:00
abstract::The records of 22 patients in whom wall thickening of the renal collecting system was seen at ultrasound (US) were retrospectively reviewed. Wall thickening was found in 15 patients with renal transplants and seven with native kidneys. Severe thickening occurred with transplant rejection, but thickening also occurred ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.168.2.3293110
更新日期:1988-08-01 00:00:00
abstract::Lung abscesses were drained by means of catheters guided by computed tomography (CT) in 19 patients who still had sepsis despite standard medical therapy; all patients had received antibiotics for at least 5 days, and 11 of the 19 patients had undergone bronchoscopy. The abscess was cured (by clinical and radiographic...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.178.2.1987590
更新日期:1991-02-01 00:00:00
abstract::Purpose To determine the feasibility of using intraesophageal radiofrequency (RF) hyperthermia to enhance local chemotherapy in a rat model with orthotopic esophageal squamous cancers. Materials and Methods The animal protocol was approved by the institutional animal care and use committee and the institutional review...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2016152281
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To evaluate the elasticity of the coracohumeral ligament (CHL) in healthy individuals and patients with clinical findings suggestive of unilaterally involved adhesive capsulitis of the shoulder (ACS). MATERIALS AND METHODS:The institutional review board approved this single-institution prospective study, which...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2015150888
更新日期:2016-02-01 00:00:00
abstract::Although infrequent, esophageal rupture is a serious complication of pneumatic dilatation for the treatment of achalasia. Because of an experience with delayed recognition of esophageal perforation in a patient with achalasia, we now examine the esophagus using a water-soluble contrast medium immediately following eve...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/130.3.589
更新日期:1979-03-01 00:00:00
abstract::To determine and quantify the major sources of anxiety for patients undergoing magnetic resonance (MR) imaging and to suggest means by which to eliminate or diminish their negative effects, the authors studied anxiety in 46 subjects. Of these, 20 randomly selected subjects who successfully completed the examination pa...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.170.2.2911670
更新日期:1989-02-01 00:00:00
abstract::Three cases of a basilar/middle meningeal artery anastomosis are demonstrated angiographically. No reference to previous angiographic demonstration of this vascular anomaly has been found in the literature, and only one similar case with an anatomical description has been located. An embryological explanation of this ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/118.2.367
更新日期:1976-02-01 00:00:00
abstract:PURPOSE:To test previously defined ultrasound (US) criteria for identification of partial-thickness tears of the rotator cuff. MATERIALS AND METHODS:Before shoulder arthroscopy, 52 patients with shoulder pain for more than 3 months were examined with a 7.5-MHz commercially available linear-array transducer and a stand...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.197.2.7480690
更新日期:1995-11-01 00:00:00
abstract::The radiopharmaceutical iodine 131 metaiodobenzylguanidine (I-131 MIBG) has been shown to locate pheochromocytomas scintigraphically with a false-negative rate of approximately 13%. To improve image quality and reduce the false-negative rate, I-123 was examined as a radioactive label for MIBG, as it has many advantage...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.155.3.4001380
更新日期:1985-06-01 00:00:00
abstract::Ultrasound-guided compression repair (UGCR) of catheterization-related femoral artery injuries was evaluated as a possible new imaging-guided interventional procedure. Thirty-nine femoral artery injuries (35 pseudoaneurysms, four arteriovenous fistulas) were detected with color Doppler flow imaging in patients with en...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.178.3.1994400
更新日期:1991-03-01 00:00:00
abstract::A simple method of shielding the hand during cross-compression angiography is described. A standard lead glove with the fingertips cut out of the palmar aspect is used, allowing sensation and mobility while still protecting the hand. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/128.2.509
更新日期:1978-08-01 00:00:00
abstract::Prototype surface coil magnetic resonance (MR) images were obtained from phantoms and 42 subjects at 0.6 T to assess the feasibility of imaging relatively deep abdominal structures. Surface coil images demonstrated a two- to fourfold improvement in signal-to-noise ratio (SNR) when compared with whole-body coil images ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.157.2.4048450
更新日期:1985-11-01 00:00:00
abstract::The ability to resolve the fine linear structures of interstitial lung disease is one measure of the limiting performance characteristics of an imaging system. Conventional screen-film radiography was compared with six algorithms of isodose storage phosphor digital radiography (0.2-mm x 10-bit pixel matrix) in the det...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.178.3.1994410
更新日期:1991-03-01 00:00:00
abstract:PURPOSE:To describe a benign nodular lesion in the peripheral zone (PZ) of the prostate gland. MATERIALS AND METHODS:In 1,087 patients, the features of 722 focal lesions in the PZ or central zone of the prostate on transrectal ultrasound (TRUS) scans were retrospectively compared with histologic findings in biopsy sam...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.189.3.7694310
更新日期:1993-12-01 00:00:00
abstract::Pelvic sonograms from 61 consecutive patients with suspected ectopic pregnancy and an additional 17 proved ectopic pregnancy cases were reviewed retrospectively. Special attention was given to the appearance of the uterus and intrauterine fluid collections in the absence of a fetal pole. Criteria for the exclusion of ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.143.1.7063730
更新日期:1982-04-01 00:00:00
abstract:PURPOSE:To assess the anatomic development of native arteriovenous fistula (AVF) during the first 6 weeks after creation by using ultrasonographic (US) measurements in a multicenter hemodialysis fistula maturation study. MATERIALS AND METHODS:Each institutional review board approved the prospective study protocol, and...
journal_title:Radiology
pub_type: 杂志文章,多中心研究
doi:10.1148/radiol.2015150385
更新日期:2016-05-01 00:00:00
abstract::Background Comprehensive assessments of the frequency and associated doses from radiologic and nuclear medicine procedures are rarely conducted. The use of these procedures and the population-based radiation dose increased remarkably from 1980 to 2006. Purpose To determine the change in per capita radiation exposure i...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2020192256
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To compare changes in urinary viscosity in the renal tubules following administration of a high-viscosity iso-osmolar contrast agent (iodixanol) to that observed following administration of a less viscous, higher osmolar contrast agent (iopromide) in anesthetized rats. MATERIALS AND METHODS:A total of 43 rats ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.10091485
更新日期:2010-08-01 00:00:00