Abstract:
:Periprosthetic Joint Infection (PJI) represents one of the leading causes of revision prosthetic surgery, accounting for 25% of failed Total Knee Replacement (TKR) and 15% of failed Total Hip Replacement (THR). The search for a biomarker that, together with clinical and radiological findings, could improve the management of such a kind of patients is currently a big challenge for orthopaedic surgeons. This review aims (1) to assess the accuracy and the limitations of the traditional (Serum Erythrocytes Sedimentation Rate, C-reactive Protein, Procalcitonin, Interleukin 6, Tumor Necrosis Factor alpha), (2) and to analyse the emerging serum biomarkers (Presepsin, Toll-like Receptor 2, soluble urokinase-type Plasminogen Activator Receptor, Chemokine Ligand 2 and Osteopontin) in the diagnosis of PJI. A special attention will be given to the emerging serum biomarkers, that could play an important role as first-line investigations, in the screening of PJI in a close future.
journal_name
Eur Rev Med Pharmacol Scijournal_title
European review for medical and pharmacological sciencesauthors
Vicenti G,Bizzoca D,Nappi V,Pesce V,Solarino G,Carrozzo M,Moretti F,Dicuonzo F,Moretti Bdoi
10.26355/eurrev_201904_17473subject
Has Abstractpub_date
2019-04-01 00:00:00pages
43-50issue
2 Suppleissn
1128-3602issn
2284-0729journal_volume
23pub_type
杂志文章,评审abstract::No Abstract Available. ...
journal_title:European review for medical and pharmacological sciences
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journal_title:European review for medical and pharmacological sciences
pub_type: 杂志文章,评审
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更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Functional pelvic disorders in patients undergoing conservative surgical approach for rectal cancer are considered a major public health issue and represent one third of cost of colorectal cancer. We investigated the hypothesis that lymphadenectomy, involves the pelvic floor results in a localized hides or s...
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更新日期:2018-12-01 00:00:00
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更新日期:2019-08-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-02-01 00:00:00
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