Abstract:
INTRODUCTION:In multiple sclerosis (MS), spinal cord imaging can help in diagnosis and follow-up evaluation. However, spinal cord magnetic resonance imaging (MRI) is technically challenging, and image quality, particularly in the axial plane, is typically poor compared to brain MRI. Because gradient-recalled echo (GRE) images might offer improved contrast resolution within the spinal cord at high magnetic field strength, both without and with a magnetization transfer prepulse, we compared them to T2-weighted fast-spin-echo (T2-FSE) images for the detection of MS lesions in the cervical cord at 3T. METHODS:On a clinical 3T MRI scanner, we studied 62 MS cases and 19 healthy volunteers. Axial 3D GRE sequences were performed without and with off-resonance radiofrequency irradiation. To mimic clinical practice, all images were evaluated in conjunction with linked images from a sagittal short tau inversion recovery scan, which is considered the gold standard for lesion detection in MS. Two experienced observers recorded image quality, location and size of focal lesions, atrophy, swelling, and diffuse signal abnormality independently at first and then in consensus. RESULTS:The number and volume of lesions detected with high confidence was more than three times as high on both GRE sequences compared to T2-FSE (p < 0.0001). Approximately 5 % of GRE scans were affected by artifacts that interfered with image interpretation, not significantly different from T2W-FSE. CONCLUSIONS:Axial 3D GRE sequences are useful for MS lesion detection when compared to 2D T2-FSE sequences in the cervical spinal cord at 3T and should be considered when examining intramedullary spinal cord lesions.
journal_name
Neuroradiologyjournal_title
Neuroradiologyauthors
Ozturk A,Aygun N,Smith SA,Caffo B,Calabresi PA,Reich DSdoi
10.1007/s00234-012-1118-5subject
Has Abstractpub_date
2013-03-01 00:00:00pages
431-9issue
4eissn
0028-3940issn
1432-1920journal_volume
55pub_type
杂志文章相关文献
NEURORADIOLOGY文献大全abstract::We performed MRI on 27 patients with clinically proven temporal lobe epilepsy (TLE), all with prior EEG lateralisation, and 10 volunteers, studied to evaluate disparity in size arising from biological variation (group 1). Three-dimensional spoiled GRASS (3DSPGR) sequences provided 2-mm contiguous sections of the limbi...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050465
更新日期:1997-08-01 00:00:00
abstract::A 45-year-old woman developed a myelopathy 9 years after a spontaneous left caroticocavernous fistula (CCF) was treated by a trapping procedure, with clipping distal to the fistula and ligation of the common carotid artery. Spinal MRI and vertebral angiography revealed recurrence of the CCF and gigantic tortuous veins...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00596510
更新日期:1992-01-01 00:00:00
abstract::We report aqueduct compression by venous ectasia in a 65-year-old man with a dural arteriovenous fistula in the posterior cranial fossa draining into a superior vermian vein. Conventional and phase-contrast MRI showed the aqueduct stenosis and the causative dilated vein. ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050883
更新日期:2000-04-01 00:00:00
abstract::Gadodiamide injection, a new nonionic, MRI contrast medium, was compared with the ionic agent gadolinium (Gd)-DTPA at 0.1 mmol/kg body weight in a double-blind, randomised trial in 60 patients, 30 receiving each substance, with known or suspected lesions of the central nervous system. The patients were closely questio...
journal_title:Neuroradiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01578263
更新日期:1995-04-01 00:00:00
abstract:INTRODUCTION:The possibility of recanalization and the need for retreatment are the most important limitations of intracranial aneurysm embolization. The purpose of the study was to compare the size of aneurysm remnants measured at follow-up with three-dimensional digital subtracted angiography (3D-DSA) and magnetic re...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-012-1063-3
更新日期:2012-12-01 00:00:00
abstract::We report two instructive cases of ruptured dissecting aneurysm of the basilar artery. Although stent-assisted endovascular treatment was successful, recurrent bleeding occurred 4 h after the procedure in one patient, and the other's basilar artery occluded 6 days after the procedure. These cases suggest that the high...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-002-0903-y
更新日期:2003-01-01 00:00:00
abstract::It is shown-taking in consideration the local circumstances-that the EMI scanning of the brain is less expensive than pneumoencephalography percutaneus carotid angiography or cerebral four vessel angiography. ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00346076
更新日期:1976-07-30 00:00:00
abstract::We reconstructed three-dimensional (3D) surface images from single-photon emission computed tomography (SPECT) data using N-isopropyl-p[123I]-iodoamphetamine (123I-IMP) in 27 patients with Parkinson's disease and 11 normal control subjects. The 3D reconstruction was performed using distance-shaded methods at threshold...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00593259
更新日期:1994-05-01 00:00:00
abstract:PURPOSE:Brain volume changes (BVC) on therapy in MS are being considered as predictor for treatment response at an individual level. We ought to assess whether adding BVC as a factor to monitor interferon-beta response improves the predictive ability of the (no) evidence of disease activity (EDA-3) and Río score (RS-3)...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-020-02604-8
更新日期:2020-11-25 00:00:00
abstract::It is possible to underestimate the grade of nonenhancing cerebral tumours on conventional contrast-enhanced MRI or CT. Differentiation of high- and low-grade gliomas by measurement of the brain-blood partition coefficient lambda (T lambda) with Xe-enhanced CT (XeCT) has been reported. We assessed the practical applic...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050481
更新日期:1997-09-01 00:00:00
abstract::Bilateral conductive deafness due to congenital absence of the long process of the incus (CALPI) is rare. The authors present the case of a patient with bilateral CALPI. To the best of our knowledge, this is the first reported case preoperatively diagnosed as bilateral CALPI by computed tomography. Multislice computed...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-004-1200-8
更新日期:2004-10-01 00:00:00
abstract::We describe an atypical MRI appearance of multiple sclerosis (MS). Lesions characterized on T2-weighted images by a well-defined rim of increased signal intensity and a concentric region of higher signal intensity were seen in 6 of 132 patients with MS. On T1-weighted images these lesions were evident as regions of lo...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00588333
更新日期:1995-05-01 00:00:00
abstract::A 35-year-old woman presented with a 6-month history of intermittent headaches, vomiting and dizziness. CT showed a plaque-like mass with tiny calcifications along the surface of the left frontal lobe. The mass exhibited heterogeneous enhancement with a few low-density foci. Underlying sulcal obliteration and enhancem...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00607273
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:Supratentorial pilocytic astrocytoma (PA) may mimic pleomorphic xanthoastrocytoma (PXA) on conventional MR imaging, and a differentiation is clinically important because of distinct recurrence rate and anaplastic transformation rate. The purpose of this study was to investigate the diagnostic potential of diffu...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-018-2036-y
更新日期:2018-07-01 00:00:00
abstract::Necrotic meningiomas are relatively rare, accounting for 1.3-3.9% of primary intracranial tumours and for 10-15% of meningiomas, but are of special clinical importance as they may resemble metastases or malignant gliomas. We report the magnetic resonance findings of diffusion-weighted imaging, perfusion-weighted imagi...
journal_title:Neuroradiology
pub_type: 杂志文章,评审
doi:10.1007/s00234-003-1144-4
更新日期:2004-03-01 00:00:00
abstract:INTRODUCTION:Endovascular coil embolization of posterior circulation aneurysms has advantages over a surgical approach. However, the application of coil embolization is sometimes limited in wide-necked posterior inferior cerebellar artery (PICA) aneurysms, which are incorporating the origin of the branch. Presented her...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-013-1178-1
更新日期:2013-07-01 00:00:00
abstract::A case of Sotos' syndrome (cerebral gigantism) is described. Pneumencephalography, performed at the age of 15 days, revealed abnormal separation of the opercula on the right. By comparing the contours with developmental anatomical features of this area it agreed with a foetal development of 24 weeks gestational age. B...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00346862
更新日期:1980-08-01 00:00:00
abstract::Giant cell tumors are uncommon primary bone tumors. They primarily occur in the long bones. Giant cell tumors are extremely rare in the skull and head and neck. When it does occur, the maxilla and mandible are the common sites to be involved. We described two cases of giant cell tumor in the temporal bone. In the nonc...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050753
更新日期:1999-04-01 00:00:00
abstract:INTRODUCTION:Intracranial developmental venous anomalies (DVAs) are considered benign vascular dispositions; they are asymptomatic in the vast majority of cases. They represent extreme variations of the venous drainage and may rarely be responsible for focal venous ischemia leading to neurological dysfunction. The aim ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-011-0890-y
更新日期:2012-05-01 00:00:00
abstract::Regional intra-arterial drug administration has been advocated in order to reduce the risks of systemic complications in conjunction with systemic tumor chemotherapy. We have been using superselective angiographic techniques to administer the antitumor drug mitomycin C directly into the feeding arteries of the tumor i...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00395325
更新日期:1978-01-01 00:00:00
abstract::Gadolinium based MRI contrast agents are considered very safe due to their well known pharmacologic properties and elimination mechanisms. In this paper, we present a unique case in whom transient enhancement of CSF with contrast is seen. Severe renal failure is demonstrated to be responsible for this finding. The dia...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340100606
更新日期:2001-11-01 00:00:00
abstract::Posterior apophyseal ring fracture (PARF) of the lumbar spine is an uncommon injury thought usually to occur in adolescence. We analysed CT findings in 20 cases (19 patients), whose age ranged from 16 to 45 years (average 30 years). The PARF could be divided into two distinct groups on the basis of the shape and locat...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00593682
更新日期:1994-08-01 00:00:00
abstract:INTRODUCTION:Patients with type 2 diabetes mellitus (T2DM) have usually been found cognitive impairment associated with brain white matter (WM) abnormalities. However, findings have varied across studies, and any potential relationship with Alzheimer's disease (AD) remains unclear. The aim of this study was to assess t...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-016-1752-4
更新日期:2016-12-01 00:00:00
abstract::We present a case of plasma cell granuloma involving the dura mater with infiltration of the adjacent brain parenchyma. The radiological and pathological features of this entity are described. ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF02278129
更新日期:1996-05-01 00:00:00
abstract:INTRODUCTION:There are still no standardized guidelines for perfusion computerized tomography (PCT) analysis. METHODS:A total of 61 PCT studies were analyzed using either the anterior cerebral artery (ACA) or the middle cerebral artery (MCA) as the arterial reference, and the superior sagittal sinus (SSS) or the vein ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-006-0099-7
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:Coiling associated with placement of a self-expandable intracranial stent has improved the treatment of intracranial wide-necked aneurysms. Little is known, however, about the durability of this treatment. The purpose of this report is to present our experience with the LEO stent and to evaluate the complicatio...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-017-1965-1
更新日期:2018-02-01 00:00:00
abstract::The characteristic findings on computed tomography (CT) in multiple sclerosis (MS) are discussed. In a series of 49 cases plain CT was normal in 21 (43%), cerebral atrophy alone was present in 17 (35%) and plaques were visible in 11 (23%). These were most often adjacent to the lateral ventricles (14 plaques) and in th...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00329059
更新日期:1978-05-31 00:00:00
abstract::MRI was used to study possible morphological changes in the visual system in 12 patients suffering from congenital blindness of peripheral (ocular) origin. While their optical pathways showed degeneration, hypoplasia or atrophy in 7 out of 12 cases, the occipital cortex appeared normal in all cases. This dissociation ...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s002340050616
更新日期:1998-07-01 00:00:00
abstract::Five patients have been selected to demonstrate the diagnostic accuracy of CT in cases of traumatic damage to the base of the skull and spine in infants and children. Ct is superior to any other diagnostic radiological technique as bone and soft tissues are usually equally well demonstrated during one visit to the Rad...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/BF00344607
更新日期:1981-01-01 00:00:00
abstract:INTRODUCTION:Metaplastic ossification is a rare event in nasal polyps. The purpose of this study was to review the computed tomography (CT) and magnetic resonance (MR) imaging findings of nasal polyps with metaplastic ossification. METHODS:CT (n=5) and MR (n=3) images of five patients (four men and one woman; mean age...
journal_title:Neuroradiology
pub_type: 杂志文章
doi:10.1007/s00234-010-0758-6
更新日期:2010-12-01 00:00:00