Abstract:
:We reconstructed three-dimensional (3D) surface images from single-photon emission computed tomography (SPECT) data using N-isopropyl-p[123I]-iodoamphetamine (123I-IMP) in 27 patients with Parkinson's disease and 11 normal control subjects. The 3D reconstruction was performed using distance-shaded methods at threshold levels with an interval of 5% from 45-80%. Any area of decreased perfusion at each threshold level was visualised as a defect area by the algorithm. In nondemented patients with Parkinson's disease, perfusion defects were frequently found in the parietal cortex at a threshold value of 65%. In demented patients, perfusion defects were frequently seen at thresholds of 45-65%, and were more marked in the temporal and parietal cortex bilaterally. This suggests that dementia in Parkinson's disease is related to a reduction of perfusion in the temporoparietal cortex.
journal_name
Neuroradiologyjournal_title
Neuroradiologyauthors
Tachibana H,Kawabata K,Tomino Y,Sugita M,Fukuchi Mdoi
10.1007/BF00593259subject
Has Abstractpub_date
1994-05-01 00:00:00pages
276-80issue
4eissn
0028-3940issn
1432-1920journal_volume
36pub_type
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