Comparison between stenting and conservative management of posterior circulation perforator aneurysms: Systematic review and case series.


PURPOSE:Posterior circulation perforator aneurysms (PCPAs) are a rare type of intracranial aneurysms whose natural history and optimal clinical management are still largely unexplored. This study aims to report our experience with treating ruptured PCPAs and to provide a systematic review of the literature to compare the two most established treatment options, endovascular stenting, and conservative management including administration of antifibrinolytic drugs and watchful waiting. METHODS:We performed a systematic review of the literature following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Major databases were searched for case reports and case report series written in the English language between 1995 and 2020. Additionally, we retrospectively reviewed our stroke center database for cases of ruptured PCPAs between January 2014 and July 2020. Endovascular stenting and conservative treatment were compared using endpoints, including favorable outcome rate (mRS 0-2), occlusion rate, mortality rate, periinterventional complication rate, and re-hemorrhage rate. RESULTS:We identified 31 patients treated endovascularly using stents and 33 patients treated conservatively, with the administration of antifibrinolytic drugs in 3 of them. Our analysis showed no statistically significant difference between the groups, except for the occlusion rate. CONCLUSIONS:The optimal management strategy of PCPAs is still unknown, but stenting can be considered as an effective occlusion method with an acceptable complication rate. Preventive ventricular drainage may be necessary due to the high hydrocephalus rate encountered in ruptured PCPAs.






Gardijan D,Herega T,Premužić V,Jovanović I,Ozretić D,Poljaković Z,Radoš M




Has Abstract


2021-01-06 00:00:00








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    pub_type: 杂志文章


    authors: Dumas JL,Visy JM,Belin C,Gaston A,Goldlust D,Dumas M

    更新日期:1997-01-01 00:00:00

  • Hema and latex: a dangerous combination?

    abstract::The endovascular treatment of intracranial aneurysms with detachable balloons requires filling materials that harden reliably and are compatible with the balloon. While the incompatibility of latex balloons and hema from different manufacturers is known, no incompatibility has been assumed thus far if both balloon and...


    pub_type: 杂志文章


    authors: Forsting M,Sartor K

    更新日期:1991-01-01 00:00:00

  • Procedure-related haemorrhage in embolisation of intracranial aneurysms with Guglielmi detachable coils.

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    pub_type: 杂志文章


    authors: Kwon BJ,Han MH,Oh CW,Kim KH,Chang KH

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    pub_type: 杂志文章,多中心研究


    authors: Manara R,Brotto D,Bugin S,Pelizza MF,Sartori S,Nosadini M,Azzolini S,Iaconetta G,Parazzini C,Murgia A,Peron A,Canevini P,Labriola F,Vignoli A,Toldo I

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    abstract::Nine men with dural arteriovenous malformations (DAVM) at the base of the anterior cranial fossa are described. Four patients had intracerebral haemorrhage and four had seizures, associated with haemorrhage in two. In three cases the fistula was an incidental finding. In five cases the diagnosis could be made before a...


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    更新日期:1993-01-01 00:00:00

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  • Atlantoaxial instability in Marfan's syndrome. Diagnosis and treatment. A case report.

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    更新日期:1981-02-01 00:00:00

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    authors: van den Hauwe L,Parizel PM,Martin JJ,Cras P,De Deyn P,De Schepper AM

    更新日期:1995-07-01 00:00:00

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    authors: Manfrè L,De Vivo AE,Al Qatami H,Ventura F,Zobel B,Midiri M,Chandra RV,Carter NS,Hirsch J

    更新日期:2020-09-01 00:00:00

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    更新日期:1997-06-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:1990-01-01 00:00:00

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  • Lung metastasis of a meningioma.

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    pub_type: 杂志文章


    authors: Wende S,Bohl J,Schubert R,Schulz V

    更新日期:1983-01-01 00:00:00

  • Gadolinium deposition within the dentate nucleus and globus pallidus after repeated administrations of gadolinium-based contrast agents-current status.

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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章


    authors: Nigro P,Chiappiniello A,Simoni S,Paolini Paoletti F,Cappelletti G,Chiarini P,Filidei M,Eusebi P,Guercini G,Santangelo V,Tarducci R,Calabresi P,Parnetti L,Tambasco N

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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Gibson RD,Cowan IA

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    pub_type: 杂志文章


    authors: Hiramatsu K,Utsumi S,Kyoi K,Sakaki T,Tada T,Iwasaki S,Kichikawa K

    更新日期:1991-01-01 00:00:00

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    pub_type: 杂志文章


    authors: Zimmerman RA,Bilaniuk LT,Grossman RI,Levine RS,Lynch R,Goldberg HI,Samuel L,Edelstein W,Bottomley P,Redington RW

    更新日期:1985-01-01 00:00:00

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    authors: Bateman GA,Levi CR,Schofield P,Wang Y,Lovett EC

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    pub_type: 杂志文章


    authors: Eley KA,Delso G

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    pub_type: 杂志文章


    authors: Heiniger P,el-Koussy M,Schindler K,Lövblad KO,Kiefer C,Oswald H,Wissmeyer M,Mariani L,Donati F,Schroth G,Weder B

    更新日期:2002-06-01 00:00:00

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    pub_type: 杂志文章


    authors: Onda K,Tanaka R,Takahashi H,Takeda N,Ikuta F

    更新日期:1990-01-01 00:00:00