Electronic health record year and country of birth testing and patient navigation to increase diagnosis of chronic viral hepatitis.

abstract：:In Italy, HDV infection endemicity has greatly decreased overtime. Migratory flow may change this scenario as migrants often come from high HDV endemicity areas. Here, we studied characteristics of HDV infection in Italy, particularly addressed to the birth area of subjects. Chronic HBsAg carriers consecutively referr...

journal_title：Journal of viral hepatitis

authors： Stroffolini T,Ciancio A,Furlan C,Vinci M,Fontana R,Russello M,Colloredo G,Morisco F,Coppola N,Babudieri S,Ferrigno L,Sagnelli C,Sagnelli E

更新日期：2020-09-01 00:00:00

abstract：:Only in a minority of patients with chronic hepatitis B (CHB) will treatment with interferon (IFN)-alpha or nucleoside analogues lead to sustained virological response. In vivo immunization (IVI) following virus suppression aims to optimize conditions for an effective immune response: following rapid and profound viru...

journal_title：Journal of viral hepatitis

authors： Sprengers D,van der Molen RG,Binda R,Kusters JG,de Man RA,Niesters HG,Schalm SW,Janssen HL

更新日期：2007-10-01 00:00:00

abstract：:Portal hypertension and splenomegaly are common in patients with cirrhosis. However, there is limited previous in vivo research on the correlation between spleen stiffness and stages of liver fibrosis. This study aimed to evaluate the diagnostic value of spleen stiffness measurement (SSM), using acoustic radiation for...

journal_title：Journal of viral hepatitis

authors： Chen SH,Li YF,Lai HC,Kao JT,Peng CY,Chuang PH,Su WP,Chiang IP

更新日期：2012-09-01 00:00:00

abstract：:Cameroon is thought to have one of the highest prevalences of hepatitis C virus (HCV) infection in the world (4.9% among adults). A marked cohort effect exists in several communities where ≈50% of the elderly are infected. Better assessment of HCV distribution is needed for planning treatment programmes. We tested for...

journal_title：Journal of viral hepatitis

authors： Njouom R,Siffert I,Texier G,Lachenal G,Tejiokem MC,Pépin J,Fontanet A

更新日期：2018-08-01 00:00:00

abstract：:Drug users with chronic hepatitis C virus (HCV) infection are frequently co-infected with human immunodeficiency virus-1 (HIV-1), but it is still not clear whether HIV-1 worsens the natural history of hepatitis C. To investigate this, we conducted a multicentre observational study in 163 drug addicts with histological...

journal_title：Journal of viral hepatitis

authors： Romeo R,Rumi MG,Donato MF,Cargnel MA,Viganò P,Mondelli M,Cesana B,Colombo M

更新日期：2000-07-01 00:00:00

abstract：:Our study was conducted to further investigate the single-dose approach of hepatitis A vaccination, while providing supportive data on the flexibility of booster administration. Participants received at least one dose of Avaxim 80U Pediatric at 11-23 months of age, and they will be followed for 10 years. We report her...

journal_title：Journal of viral hepatitis

authors： Espul C,Benedetti L,Linares M,Cuello H,Rasuli A

更新日期：2015-04-01 00:00:00

abstract：:High-dose induction with alpha-interferon induces early viral clearance of hepatitis C and combined with ribavirin enhances sustained response. We assess whether adding ribavirin after viral clearance obtained by alpha-interferon induction increased the rate of viral eradication.Forty-one naïve patients with chronic h...

journal_title：Journal of viral hepatitis

authors： Di Marco V,Ferraro D,Almasio P,Vaccaro A,Parisi P,Cappello M,Cino N,Di Stefano R,Craxì A

更新日期：2002-09-01 00:00:00

abstract：:Chronic non-A, non-B hepatitis (NANBH) is a common and often progressive liver disease. Based on current serological tests, hepatitis C virus (HCV) infection is responsible for most cases. Interferon-alpha (IFN) treatment at a dose of 3 x 10(6) units given three times per week for 24 weeks has been shown to be effecti...

journal_title：Journal of viral hepatitis

authors： Davis GL,Lindsay K,Albrecht J,Bodenheimer HC Jr,Balart LA,Perrillo RP,Dienstag JL,Tamburro C,Schiff ER,Carey W

更新日期：1994-01-01 00:00:00

abstract：:CD4+ T cells are thought to contribute to antiviral immune responses by secretion of cytokines thereby providing help to CD8+ T and B cells. However, perforin-positive cytotoxic CD4+ T cells have been described in human immunodeficiency virus-positive patients suggesting a role not only of CD8+ but also of CD4+ T cell...

journal_title：Journal of viral hepatitis

authors： Aslan N,Yurdaydin C,Wiegand J,Greten T,Ciner A,Meyer MF,Heiken H,Kuhlmann B,Kaiser T,Bozkaya H,Tillmann HL,Bozdayi AM,Manns MP,Wedemeyer H

更新日期：2006-08-01 00:00:00

abstract：:Understanding local viral hepatitis and HIV epidemiology is essential if WHO elimination targets are to be achieved. We demonstrate a consistently high prevalence of undiagnosed active infection in urban emergency department attendees in England, with variations in local risk groups crucial to informing targeted testi...

journal_title：Journal of viral hepatitis

authors： Hopkins MJ,Todd S,Beadsworth M,Anderson C,Mohamed Z,Muir D,Vivancos R,Brown AS,Ruf M,Chawla A

更新日期：2020-01-01 00:00:00

abstract：:In chronic hepatitis C, transient elastography (TE) accurately identifies cirrhosis, but its ability to assess significant fibrosis (Metavir > or = F2) is variable. Constitutional and liver disease-related factors may influence TE and here we examined the variables associated with differences. Three hundred consecutiv...

journal_title：Journal of viral hepatitis

authors： Calvaruso V,Cammà C,Di Marco V,Maimone S,Bronte F,Enea M,Dardanoni V,Manousou P,Pleguezuelo M,Xirouchakis E,Attanasio M,Dusheiko G,Burroughs AK,Craxì A

更新日期：2010-07-01 00:00:00

abstract：:Hepatitis A incidence has declined in most countries through a combination of prevention measures, augmented through the use of a highly effective vaccine. In Australia, the proportion of the population susceptible to hepatitis A infection has declined over time due to high rates of opportunistic vaccination as well a...

journal_title：Journal of viral hepatitis

authors： Jayasundara D,Hui BB,Regan DG,Heywood AE,MacIntyre CR,Wood JG

更新日期：2019-01-01 00:00:00

abstract：:This study investigated the molecular and pharmacokinetic mechanisms of the enhanced antiviral efficacy associated with pegylated interferon (PEG-IFN) alpha-2b and ribavirin. The study involved comparing the expression of serial double-stranded RNA-activated protein kinase (PKR) before and during treatment in 26 PEG-I...

journal_title：Journal of viral hepatitis

authors： Asahina Y,Izumi N,Umeda N,Hosokawa T,Ueda K,Doi F,Tsuchiya K,Nakanishi H,Matsunaga K,Kitamura T,Kurosaki M,Uchihara M,Higaki M,Miyake S

更新日期：2007-06-01 00:00:00

abstract：:The ECHO model was developed to expand access to medical care for populations with HCV infection in underserved areas. We aimed to compare HCV treatment outcomes in community-based clinics with the Austral University Hospital (AUH) and to assess improvement in physician knowledge and skills. In October 2015, we establ...

journal_title：Journal of viral hepatitis

authors： Mendizabal M,Ridruejo E,Ceballos S,Sixto M,Billordo A,Gadea C,Mengarelli S,Alonso C,Palazzo A,De María L,Bruno A,Perez D,Piñero F,Deltrozzo V,Mendoza C,Figueroa S,Manero E,Villa M,Barreyro F,Moreno V,Vilar J,Mur

更新日期：2019-11-01 00:00:00

abstract：:In this study, a comprehensive methodology for modelling the hepatitis C virus (HCV) epidemic is proposed to predict the future disease burden and assess whether the recent decline in the incidence of HCV may affect the future occurrence of cirrhosis and hepatocellular carcinoma (HCC) cases. Using the prevalence of HC...

journal_title：Journal of viral hepatitis

authors： Sypsa V,Touloumi G,Tassopoulos NC,Ketikoglou I,Vafiadis I,Hatzis G,Tsantoulas D,Akriviadis E,Delladetsima J,Demonakou M,Hatzakis A

更新日期：2004-07-01 00:00:00

abstract：:The non-structural (NS)5A protein of hepatitis C virus (HCV) is cleaved, after translation, by the NS3-encoded zinc-dependent serine proteinase, from the NS4B protein upstream and the NS5B protein downstream. The released, mature NS5A protein is a 56 000 MW phosphoprotein (p56), which also exists within infected cells...

journal_title：Journal of viral hepatitis

authors： Pawlotsky JM,Germanidis G

更新日期：1999-09-01 00:00:00

abstract：:Limited data suggest that low T-helper cell levels may be observed in hepatitis C virus (HCV) monoinfected patients with decompensated liver disease. We sought to determine the distribution and relationship of T-helper cells (CD4) to liver fibrosis in HCV-monoinfected patients before and during pegylated interferon (P...

journal_title：Journal of viral hepatitis

authors： Rashkin S,Rouster S,Goodman ZD,Sherman KE

更新日期：2010-03-01 00:00:00

abstract：:To assess the prevalence of hepatitis delta virus (H delta V) in northern India, 204 adult patients with acute and chronic liver disease who were positive for hepatitis B virus (HBV) markers were screened for anti-H delta V antibody by enzyme-linked immunosorbent assay (ELISA). Anti-H delta V antibodies were positive ...

journal_title：Journal of viral hepatitis

authors： Singh V,Goenka MK,Bhasin DK,Kochhar R,Singh K

更新日期：1995-01-01 00:00:00

abstract：:The short-term prognosis of patients with severe acute exacerbation of chronic hepatitis B (CHB) leading to acute liver failure is extremely poor. We have reported the efficacy of corticosteroid in combination with nucleoside analogue in the early stages, but virological efficacy has not been documented. Our aim was t...

journal_title：Journal of viral hepatitis

authors： Yasui S,Fujiwara K,Nakamura M,Miyamura T,Yonemitsu Y,Mikata R,Arai M,Kanda T,Imazeki F,Oda S,Yokosuka O

更新日期：2015-02-01 00:00:00

abstract：:Interferon therapy for chronic hepatitis C reduces the risk of hepatocellular carcinoma, especially among virological and biochemical responders. However, little is known about the effect of interferon therapy on mortality. We studied the long-term effect of interferon therapy on mortality in patients with chronic hep...

journal_title：Journal of viral hepatitis

authors： Kasahara A,Tanaka H,Okanoue T,Imai Y,Tsubouchi H,Yoshioka K,Kawata S,Tanaka E,Hino K,Hayashi K,Tamura S,Itoh Y,Kiyosawa K,Kakumu S,Okita K,Hayashi N

更新日期：2004-03-01 00:00:00

abstract：:Approximately 5% of the healthy adult population respond inadequately to the commercial recombinant hepatitis B vaccines. As the recombinant vaccines all have an aluminium-based adjuvant, we tried to enhance the immune response by adding a cytokine-based adjuvant. This new adjuvant AI20, containing 20 μg recombinant h...

journal_title：Journal of viral hepatitis

authors： Koc ÖM,Savelkoul PHM,van Loo IHM,Peeters A,Oude Lashof AML

更新日期：2018-09-01 00:00:00

abstract：:Transient elastography (TE) is the reference method to obtain liver stiffness measurements (LSM), but no results are obtained in 3.1% and unreliable in 15.8%. We assessed the applicability and diagnostic accuracy of TE re-evaluation using M and XL probes. From March 2011 to April 2012 868 LSM were performed with the M...

journal_title：Journal of viral hepatitis

authors： Carrión JA,Puigvehí M,Coll S,Garcia-Retortillo M,Cañete N,Fernández R,Márquez C,Giménez MD,Garcia M,Bory F,Solà R

更新日期：2015-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a human hepatotropic virus, but many hepatoma cell lines are not permissive to this virus. In a previous study, we observed that SNU-182, SNU-398 and SNU-449 hepatoma cell lines were nonpermissive to HCV. To understand the nonpermissivity, we evaluated the ability of each cell line to suppor...

journal_title：Journal of viral hepatitis

authors： Fournier C,Hoffmann TW,Morel V,Descamps V,Dubuisson J,Brochot E,Francois C,Duverlie G,Castelain S,Helle F

更新日期：2018-01-01 00:00:00

abstract：:Testing and linkage to care are important determinants of hepatitis C virus (HCV) treatment effectiveness. Public health clinics serve populations at high risk of HCV. We investigated their potential to serve as sites for HCV testing, initiation of and linkage to HCV care. Cross-sectional study of patients accessing s...

journal_title：Journal of viral hepatitis

authors： Falade-Nwulia O,Mehta SH,Lasola J,Latkin C,Niculescu A,O'Connor C,Chaulk P,Ghanem K,Page KR,Sulkowski MS,Thomas DL

更新日期：2016-05-01 00:00:00

abstract：:Hepatitis A virus (HAV) infection is still an important issue worldwide. A distinct set of viruses encode proteins that enhance viral cap-independent translation initiation driven by an internal ribosome entry site (IRES) and suppress cap-dependent host translation. Unlike cytolytic picornaviruses, replication of HAV ...

journal_title：Journal of viral hepatitis

authors： Kanda T,Gauss-Müller V,Cordes S,Tamura R,Okitsu K,Shuang W,Nakamoto S,Fujiwara K,Imazeki F,Yokosuka O

更新日期：2010-09-01 00:00:00

abstract：:The aim of the study was to analyse the current literature regarding the mode of transmission of HCV and its global prevalence in different groups of people. A systematic review of the literature on the epidemiology of hepatitis C from 1991 to 2000 using computerized bibliographic databases which include Medline, Curr...

journal_title：Journal of viral hepatitis

authors： Memon MI,Memon MA

更新日期：2002-03-01 00:00:00

abstract：:An imbalance between cytoproliferation and apoptosis may be relevant in liver carcinogenesis. The aim of this study was to analyse these parameters in patients with chronic liver damage in relation to the aetiology of the disease. Forty-eight patients were studied: 23 had hepatitis C virus (HCV)- and 11 had hepatitis ...

journal_title：Journal of viral hepatitis

authors： Farinati F,Cardin R,Fiorentino M,D'errico A,Grigioni W,Cecchetto A,Naccarato R

更新日期：2001-01-01 00:00:00

abstract：:Chemotherapy for chronic hepatitis B virus (HBV) infection is inherently difficult for a variety of reasons that are related to unusual features of both HBV replication strategy and host cell metabolism. Previous attempts to treat chronic HBV infection using nucleoside analogues have been almost universally disappoint...

journal_title：Journal of viral hepatitis

authors： Shaw T,Locarnini SA

更新日期：1999-03-01 00:00:00

abstract：:Little is known about engagement and retention in care of people diagnosed with chronic hepatitis C (HCV) in England. Establishing a cascade of care informs targeted interventions for improving case finding, referral, treatment uptake and retention in care. Using data from the sentinel surveillance of blood-borne viru...

journal_title：Journal of viral hepatitis

authors： Simmons R,Ireland G,Irving W,Hickman M,Sabin C,Ijaz S,Ramsay M,Lattimore S,Mandal S

更新日期：2018-05-01 00:00:00

abstract：:The limitations of liver biopsy have led to the development of indirect noninvasive models for liver fibrosis assessment. We aimed to evaluate and compare the performance of 30 noninvasive models to predict fibrosis stage in treatment-naïve and treated chronic hepatitis B (CHB) patients. A total of 576 Chinese treatme...

journal_title：Journal of viral hepatitis

authors： Dong XQ,Wu Z,Zhao H,Wang GQ,China HepB-Related Fibrosis Assessment Research Group.

更新日期：2019-02-01 00:00:00