Abstract:
:Cryoprecipitate has been demonstrated to correct the bleeding abnormality of patients with some congenital (storage pool disease) and acquired (uremia) platelet abnormalities, but the reason for this effect is unknown. We found significant platelet contamination in plasma harvested to prepare fresh frozen plasma and cryoprecipitate. The platelet membrane microparticles produced by freezing and thawing of the plasma were highly concentrated in cryoprecipitate and may contribute to its therapeutic effect.
journal_name
Bloodjournal_title
Bloodauthors
George JN,Pickett EB,Heinz Rsubject
Has Abstractpub_date
1986-07-01 00:00:00pages
307-9issue
1eissn
0006-4971issn
1528-0020journal_volume
68pub_type
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