[Descriptive epidemiology and molecular genetics of hereditary breast cancer in Costa Rica].

Abstract:

:Breast cancer is first in incidence and mortality among Costa Rican women. In 2011 there is a projected 1 071 new cases. We selected 116 patients diagnosed with breast cancer and family history of breast cancer. A detailed family history and epidemiology data was obtained from each patient and a blood sample was processed for DNA extraction. We analyzed the prevalence of risk factors and BRCA1 and BRCA2 mutations. These mutations were detected by different techniques and were confirmed by direct sequencing. Six patients (5.2%) had a mutation, five of which were in the BRCA2 gene and only one in BRCA1. We found that the average age of women who carry a mutation is lower than in non-carrier women. All other risk factors analyzed were not different among carrier and non-carrier women. In addition, these results and the increased incidence of breast cancer in recent years in Costa Rica, should promote an increase in prevention policies and the establishment of efficient detection methods that allow early disease diagnosis.

journal_name

Rev Biol Trop

authors

García-Jiménez L,Gutiérrez-Espeleta G,Narod SA

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

1663-8

issue

4

eissn

0034-7744

issn

2215-2075

journal_volume

60

pub_type

杂志文章
  • Review of the South American-Antarctic triplefin fish genus Helcogrammoides (Perciformes: Tripterygiidae).

    abstract::The genus Helcogrammoides comprises three species of small, cryptic shorefishes, H. antarcticus, H. chilensis, and H. cunninghami. All three species inhabit shallow water along exposed rocky coasts. Specimens reported herein extend the known distributions of H. chilensis and H. cunninghami to the vicinity of Lima, Per...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Williams JT,Springer VG

    更新日期:2001-07-01 00:00:00

  • [Prothallia in nine species of Callipteris and its comparison with other genera of the Woodsiaceae family].

    abstract::The development of the prothallia in nine species of Callipteris Bory (Woodsiaceae), four species of Diplazium, the genus from which Callipteris has been segregated, and one species of Dryoathyrium are studied in this paper. The data obtained are compared with the development of the prothallia of several other genera ...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章,评审

    doi:

    authors: Pacheco L,Riba R

    更新日期:2003-03-01 00:00:00

  • Ground-foraging ants (Hymenoptera: Formicidae) and rainfall effect on pitfall trapping in a deciduous thorn woodland (caatinga), Northeastern Brazil.

    abstract::The semi-arid Caatinga is the fourth largest biome of Brazil, which biota still remains one of the most poorly known, especially with regard to invertebrate groups. In this study, a ground-foraging ant assemblage was surveyed during one year and the effect of rainfall on pitfall trapping was assessed. The study was pe...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v59i4.3426

    authors: Nunes FA,Segundo GB,Vasconcelos YB,Azevedo R,Quinet Y

    更新日期:2011-12-01 00:00:00

  • [Taxonomic composition and zoogeographic relations of demersal in the western coast of Baja California Sur, Mexico].

    abstract::The composition of demersal fish along the western coast of the State of Baja California Sur, Mexico, including the limit of the northern distribution of the ichthyofauna of the eastern tropical Pacific, is presented. The survey was carried out on four oceanographic cruises between autumn 2004 and March 2006. Of 220 s...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Rodríguez-Romero J,Palacios-Salgado DS,López-Martínez J,Hernández-Vázquez S,Ponce-Díaz G

    更新日期:2008-12-01 00:00:00

  • [Temporal and spatial variation of shorebirds in Barra de Navidad lagoon, Jalisco, during three non-breeding seasons].

    abstract::Resident and migratory shorebirds inhabit different kinds of wetlands such as lagoons, rivers and seashores among others. In recent years, these areas have been importantly affected by urban, agriculture and touristic activities, such as the Barra de Navidad lagoon, for which little information is available to support...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Hernández S,Serrano S,Hernández XA,Robles MI

    更新日期:2012-09-01 00:00:00

  • [Allozymatic variation in crustacea Artemia franciscana (Anostraca: Artemiidae) of Freat Salt Lake in different experimental conditions].

    abstract::Starch gel electrophoresis was used to analyze the allelic variability of four polymorphic loci (Lap-2, Lap-3, Pgm and Gpi) from a single population of Artemia franciscana (Kellogg, 1906) from the Great Salt Lake (Utah, USA), cultured under eight different experimental conditions. The organisms were cultured to the ad...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Rodríguez D,Correa F,de la Rosa-Vélez J,Escobar R,Cordero B,Alvarez Z,Sánchez R

    更新日期:2002-03-01 00:00:00

  • Development and distribution of cysts of an avirulent strain of Toxoplasma and the humoral immune response in mice.

    abstract::An avirulent T. gondii strain isolated from a owl (Glaucidium brasilianum) produces randomly distributed cysts in the brain of mice which can survive to inocula as high as 1000 oocysts. Cysts appeared for the first time after 15 days of infection. Regarding to humoral immunity development due to our TCR-2 strain, dete...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Holst I,Chinchilla M

    更新日期:1990-11-01 00:00:00

  • [Diet of the tropical freshwater fish Heterandria bimaculata (Haeckel) and Poecilia sphenops Valenciennes (Cyprinidontiformes: Poeciliidae)].

    abstract::We analyzed the diet and feeding habits of the fishes Heterandria bimaculata and Poecilia sphenops. Specimens were captured monthly in "Los Carros" damp, Morelos, Mexico (18 degrees 37' N, 98 degrees 43' W). We quantified gut content by the numerical method and by the frequency of occurrence method; and used the MacAr...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Trujillo-Jiménez P,Beto HT

    更新日期:2007-06-01 00:00:00

  • Humoral response of paracoccidioidomycosis sera in hamsters with different Venezuelan isolates.

    abstract::Humoral response of paracoccidioidomycosis sera in hamsters with different Venezuelan isolates. Paracoccidioidomycosis (PCM) is a progressive systemic mycosis caused by the fungus Paraccocidioides brasiliensis (Pb), endemic to Venezuela and Latin America. In this study, eight different Venezuelan isolates obtained fro...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v57i3.5471

    authors: Spencer LM,Mateu G,Magaldi S,García F,Mata-Essayag S

    更新日期:2009-09-01 00:00:00

  • [Ultrastructural analysis of milk fat globule membranes of colostrum and human milk].

    abstract::Lacteous fat globules with their membranes from human milk and calostrum were studied by scanning and transmission electron microscopy. The first appear as spheroidal structures with some irregularities on the surface. Under the transmission electron microscope these irregularities are composed of islets from a materi...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Hernández F

    更新日期:1983-11-01 00:00:00

  • [Karyotypes of the purple snails Plicopurpura pansa and Plicopurpura columellaris (Gastropoda: Muricidae)].

    abstract::The karyotypes of the purple snails Plicopurpura pansa (Gould, 1853) and P. columellaris (Lamarck, 1816) were established from 17 and 13 adults, respectively; and from eight capsules with embryos of P. pansa. In P. pansa were counted 59 mitotic fields in the adults and 127 in embryos; and 118 fields in P columellaris....

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Arias-Rodriguez L,González-Hermoso JP,Fletes-Regalado H,Rodriguez-Ibarra LE,Del Valle Pignataro G

    更新日期:2007-09-01 00:00:00

  • Histology of the regeneration of Paulownia tomentosa (Paulowniaceae) by organogenesis.

    abstract::Paulownia tomentosa is a fast-growing tree species with a considerable economic potential because of its value for wood as well as its high biomass production, and elevated stress tolerance. The objective of the present study was to evaluate the development of adventitious buds in leaves obtained from four-week-old sh...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: San José Mdel C,Cernadas MJ,Corredoira E

    更新日期:2014-06-01 00:00:00

  • Temporal and spatial resource use by female three-toed sloths and their young in an agricultural landscape in Costa Rica.

    abstract::The information on ecological behavior of wild sloths is very scarce. In this study we determined the home ranges and resources used by three adult female three-toed sloths (Bradypus variegatus) and their four young in an agricultural matrix of cacao (Theobroma cacao), pasture, riparian forests and living fencerows in...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Ramirez O,Vaughan C,Herrera G,Guries R

    更新日期:2011-12-01 00:00:00

  • [Diversity of ferns and lycophytes from Reserve Natural Punta Lara, Buenos Aires, Argentina].

    abstract::Punta Lara Natural Reserve shelters the relict of the Southernmost riparian forest in the world, where the flora is threatened by the anthropic expansion and by the introduction of exotic species. In this area the ferns and lycophytes grow in particular environments as marshland, grassland and marginal forest. The aim...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Giudice GE,Ramos Giacosa JP,Luján Luna M,Yañez A,de la Sota ER

    更新日期:2011-09-01 00:00:00

  • [Helminths from the fish Dormitator maculatus (Osteichthyes: Eleotridae) from Alvarado, Veracruz, Mexico].

    abstract::Dormirator maculatus (n=184) was collected in the Alvarado Lagoon, Mexico during a year period (Oct. 1993-1994). In the helminthologic review, the presence of Clinostomum complanatum (82.3%), Neoechinorhynchus golvani (76.1%), Spiroxys sp. (21.3 %), and Camallanus sp. (6.2%) was registered. Reduction of the hematocrit...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Mendoza JM,Sarabia DO,López RC,López JF

    更新日期:2004-06-01 00:00:00

  • A new species of the genus Alterosa (Trichoptera: Philopotaminae) from Southeastern Brazil.

    abstract::Philopotamidae is a large caddisfly family with 20 extant genera comprising about 1000 described species worldwide. Alterosa contains 22 described species distributed in South and Southeastern Brazil. Adults of the genus are very similar in general structure, but are remarkable for their wide variation in male genital...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v60i2.3915

    authors: Jardim GA,Dumas LL

    更新日期:2012-06-01 00:00:00

  • Early development in the mouth-brooding cichlid fish Satanoperca pappaterra (Perciformes: Cichlidae).

    abstract::The Neotropical region exhibits the largest diversity of fish worldwide; however, little is known about the early development of fish species from this region. Therefore, to contribute to this knowledge, this study aimed to morphologically describe the early stages of development (eggs, larvae and juveniles) of S. pap...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v63i1.14121

    authors: Miranda Lopes T,Garcia de Oliveira F,Bialetzki A,Antonio Agostinho A

    更新日期:2015-03-01 00:00:00

  • Effect of food plants on the volume of repellent secretion obtained in adult Zonocerus variegatus (Orthoptera: Pyrgomorphidae).

    abstract::The volume of secretion obtained from adult Zonocerus variegatus (Orthoptera: Pyrgomorphidae) was influenced by the type of food plants. Insects fed on leaves of cassava Manihot esculenta, bitter leaves Vernonia amygdalina, and a mixture of M. esculenta and Acalypha wilkesiana gave a good volume of secretion while Chr...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Idowu AB,Idowu OA

    更新日期:2001-06-01 00:00:00

  • Underwater topography determines critical breeding habitat for humpback whales near Osa Peninsula, Costa Rica: implications for marine protected areas.

    abstract::Migrating humpback whales from northern and southern feeding grounds come to the tropical waters near Osa Peninsula, Pacific of Costa Rica, to reproduce and raise their calves. Planning effective marine protected areas that encompass humpback critical habitats require data about which oceanographic features influence ...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v56i2.5610

    authors: Oviedo L,Solís M

    更新日期:2008-06-01 00:00:00

  • Description of the previously unknown tadpole of Hyalinobatrachium pulveratum (Anura: Centrolenidae).

    abstract::Egg clutches of the centrolenid Hyalinobatrachium pulveratum were sampled in four lowland locations of Costa Rica. The ontogenesis of the tadpoles of this species is documented by periodical descriptions of the larval stages. Larvae of H. pulveratum change their shape during development because of the non-equal growth...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v52i1.14912

    authors: Hoffmann H

    更新日期:2004-03-01 00:00:00

  • [History of leukemia research in Costa Rica].

    abstract::A review of leukemia worldwide is discussed, focusing on etiology, diagnosis and treatment. The history of research of this type of cancer in Costa Rica is presented through the first hospital diagnosis, the arrival of clinical and laboratory hematologists, the establishment of specialized laboratories, the local hema...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章,评审

    doi:

    authors: Jiménez Bonilla R

    更新日期:2004-09-01 00:00:00

  • [Comparison between Phyllophaga (Coleoptera: Melolonthidae) assemblages in Western Cuba].

    abstract::The Cuban archipelago has 79 Phyllophaga species with a 98.6 % of endemism, which makes the group ecologically and economically important, as some species are classified as crop pests. The aim of this study was to determine the relationship between the composition and structure of the Phyllophaga assemblages with thei...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v65i1.23286

    authors: Serrano A,Morón MÁ,Barro A,Molina G

    更新日期:2017-03-01 00:00:00

  • [Biomedical research in Revista de Biologia Tropical].

    abstract::The contributions published in Revista de Biología Tropical in the area of Biomedical Sciences are reviewed in terms of number of contributions and scope of research subjects. Biomedical Sciences, particularly Parasitology and Microbiology, constituted the predominant subject in the Revista during the first decade, re...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Gutiérrez JM

    更新日期:2002-09-01 00:00:00

  • [Palms conservation, patterns of use and diversity (Arecaceae) in rain forests from the Chocó, Colombia].

    abstract::Arecaceae is a family rich in species and provides resources for the subsistence of human groups in the tropical regions. The aim of this work was to assess the richness, diversity, composition, and use patterns of the family Arecaceae in three communities of the Medio Atrato, Chocó, Colombia, in order to obtain usefu...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Valois-Cuesta H,Martínez-Ruiz C,Rentería Cuesta YY,Sol María PH

    更新日期:2013-12-01 00:00:00

  • Spatial distribution of Guaiacum sanctum (Zygophyllaceae) seedlings and saplings relative to canopy cover in Palo Verde National Park, Costa Rica.

    abstract::The spatial distribution of individuals is a fundamental property of most species and constitutes essential information for the development of restoration and conservation strategies, especially for endangered plant species. In this paper we describe the spatial distribution of different size classes of the endangered...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v61i3.11981

    authors: Fuchs EJ,Robles T,Hamrick JL

    更新日期:2013-09-01 00:00:00

  • [Impact of two artificial reefs on diurnal artisanal fishing at gulf of Morrosquillo, Colombian Caribbean].

    abstract::Fishing activity in two artificial reefs (ARs) was monitored between August 2001 and August 2002 in the gulf of Morrosquillo, to investigate their possible impact on the fishery dynamics. We determined catch per unit effort (CPUE) and catch composition, and found 19 species in Punta de Piedra and 36 in Tolú (16 specie...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Delgadillo-Garzón O,García CB

    更新日期:2009-12-01 00:00:00

  • Characterization of a Bacillus thuringiensis strain collection isolated from diverse Costa Rican natural ecosystems.

    abstract::Costa Rican natural ecosystems are among the most diverse in the world. For this reason, we isolated strains of the entomopathogenic bacteria Bacillus thuringiensis (Bt) to determine their diversity, distribution and abundance. A total of 146 Bt strains were obtained from environmental samples collected from diverse n...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v54i1.13981

    authors: Arrieta G,Espinoza AM

    更新日期:2006-03-01 00:00:00

  • Phenology and recruitment of Caryocar costaricense (Caryocaceae), an endemic tree species of Southern Central America.

    abstract::Basic aspects of the reproductive biology are largely unknown for most tropical tree species, although they are important elements to understand the impacts of anthropogenic activities as logging and forest fragmentation on these populations. In this study, data are presented on leaf and reproductive phenology, fruit ...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:10.15517/rbt.v57i3.5491

    authors: Solís S,Lobo J,Grimaldo M

    更新日期:2009-09-01 00:00:00

  • [Body size and fecundity of Juxtafabia muliniarum (Brachyura: Pinnotheridae) associated with Saccostrea palmula (Bivalvia: Ostreidae), Costa Rica].

    abstract::Size and fecundity observations of pea crab (Juxtafabia muliniarum) from the paleal cavity of the oyster Saccostrea palmula were made from May 1998 to May 1999. Infestation frequency was 18.52% in a sample of 540 oysters. Of 136 pea crabs, 36% were couples, 60% were single females and 4% were single males. The mean ca...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Cabrera Peña J,Protti Quesada M,Urriola Hernández M,Sáenz Vargas O,Alfaro Hidalgo R

    更新日期:2001-09-01 00:00:00

  • [Floristic composition and structure of a premontane moist forest in Central Valley of Costa Rica].

    abstract::The floristic composition and structure of a premontane moist forest remnant were studied in the El Rodeo Protected Zone, Central Valley of Costa Rica. Three one-hectare plots were established in the non-disturbed forest, and all trees with a diameter at breast height (dbh) of 10 cm or greater were marked, measured an...

    journal_title:Revista de biologia tropical

    pub_type: 杂志文章

    doi:

    authors: Cascante A,Estrada A

    更新日期:2001-03-01 00:00:00