Abstract:
BACKGROUND:Along with conventional periodontal surgical therapy, local delivery of antibiotics may provide more effective treatment in smokers by targeting tissue-invasive bacteria. The aim of this randomized, placebo-controlled, double-masked clinical trial was to evaluate the adjunctive effects of subgingivally delivered 0.5% azithromycin (AZM) as an adjunct to scaling and root planing (SRP) in the treatment of chronic periodontitis in smokers. METHODS:Fifty-four patients were randomized and categorized into two treatment groups: Group 1 - 26 subjects who received (SRP) plus placebo gel and Group 2 - 28 subjects who received (SRP) plus 0.5% azithromycin. Clinical parameters were recorded at baseline, 3, 6 and 9 months. They included Plaque Index (PI), modified Sulcus Bleeding Index (mSBI), probing depth (PD) and clinical attachment level (CAL). RESULTS:Azithromycin resulted in significant improvements. A single application of AZM resulted in attachment gain at 9 months of 2.44 ± 0.64 mm as compared to 0.18 ± 0.68 mm for the placebo. Similarly, pocket depth and PI were significantly reduced but no change in the mSBI was noted. CONCLUSIONS:When compared to the placebo, the adjunctive use of 0.5% AZM resulted in significant improvement in clinical outcome in the treatment of chronic periodontitis among smokers.
journal_name
Aust Dent Jjournal_title
Australian dental journalauthors
Pradeep AR,Bajaj P,Agarwal E,Rao NS,Naik SB,Kalra N,Priyanka Ndoi
10.1111/adj.12019subject
Has Abstractpub_date
2013-03-01 00:00:00pages
34-40issue
1eissn
0045-0421issn
1834-7819journal_volume
58pub_type
杂志文章,随机对照试验abstract::The aesthetic restorative glass ionomer cements undergo a rather prolonged setting reaction during which time they are susceptible to water uptake and water loss. If they can be maintained in isolation long enough in the oral cavity then the clinical result will be superior. A further series of surface treatments has ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1989.tb04641.x
更新日期:1989-08-01 00:00:00
abstract::Oral mucosal ulceration is a common manifestation of various disease processes. Identification of the aetiological factor(s) involved greatly facilitates the management of such conditions. This report describes oral ulceration of the mucosa overlying the lingual shelf and mylohyoid ridge of the mandible and, less comm...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2003.tb00011.x
更新日期:2003-03-01 00:00:00
abstract::The restorative dentist is often faced with difficulties in overcoming functional, cosmetic, and cleansibility requirements when replacing teeth in areas of localized alveolar ridge resorption. A case report is presented highlighting a surgical technique to correct such an alveolar ridge deficit. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1990.tb03025.x
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:This study compares diamond burs and curettes by clinical, microbiological, biochemical and scanning electron microscopic parameters and treatment time data in the non-surgical periodontal treatment of patients with chronic periodontitis. METHODS:Two quadrants of each of the 12 patients received root planin...
journal_title:Australian dental journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/adj.12602
更新日期:2018-06-01 00:00:00
abstract::A recent study investigated attitudes of selected Australian and British dental academics to aspects of educational management. This paper reviews that study and comments upon significant differences which were detected between the national samples. Analysis was by sub-programme CROSSTABS of the Statistical Package fo...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1982.tb04061.x
更新日期:1982-04-01 00:00:00
abstract::The delivery of effective information flow through self learning, critical thinking and problem solving is one of the objectives of current curriculum development within the Dental Faculty of the University of Hong Kong. These objectives reflect a desire to encourage skills related to 'comprehension learning' and 'mea...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1992.tb00828.x
更新日期:1992-02-01 00:00:00
abstract::Maxillary molar teeth may have accessory roots. The aim of this paper is to review and discuss the endodontic implications of this anatomical variation. A review of the literature was undertaken to identify studies and reported cases where accessory roots have been recorded in maxillary molar teeth. The results show t...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2012.01678.x
更新日期:2012-06-01 00:00:00
abstract::In order to predictably achieve bacteria-free root canal systems, especially in pulpless teeth, it is necessary to use intra-canal medicaments. Medicaments can also be used to influence the peri-radicular response to endodontic treatment. Consideration of a material's therapeutic action must be made when selecting a m...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.1990.tb04678.x
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:The prevalence of enamel defects in the first permanent molars among children has been reported to be high and may be on the increase, particularly in the European countries. Little information is available on the prevalence of enamel defects in the first permanent molars among children in Australia. The aim...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2008.00057.x
更新日期:2008-09-01 00:00:00
abstract::Comment is made regarding the cost, related to working properties, of non-precious metal alloys compared to precious metal alloys for ceramics and their possible potential for the production of allergic response. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1977.tb04435.x
更新日期:1977-02-01 00:00:00
abstract::Failure to treat the soft tissue component of dento-alveolar wounds may complicate wound healing mechanisms, retarding the rate of healing and increasing the risk of infection. A case is presented of a five-year-old with an intra-oral wound which, left untreated for eleven days, failed to resolve. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1993.tb05515.x
更新日期:1993-10-01 00:00:00
abstract::A study of 4,278 country and city kindergarten children living in South Australia showed 63 and 59 per cent received fluoride tablets at some time and 17 per cent received daily doses. Lower dmf scores were found in those taking fluoride tablets but of decreasing value in the older children. Where no fluoride was take...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1975.tb03507.x
更新日期:1975-02-01 00:00:00
abstract::A survey of 1,658 homebound and institutionalized persons suggested that about 7,000 chronically ill South Australians may need dental care and that such treatment is currently unavailable to the great majority of them. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1979.tb03618.x
更新日期:1979-04-01 00:00:00
abstract::The benefit of a public sector sealant programme for children in Australia is yet to be established. This study evaluated sealants placed by therapists of the School Dental Service in Victoria, between 1989 and 1994, on permanent teeth of children in 15 primary schools in Melbourne. Seven hundred and seventy four chil...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1997.tb00127.x
更新日期:1997-08-01 00:00:00
abstract::The discovery of a radiolucency within an unerupted tooth is a rare occurrence. One cause is external resorption. The clinical features, the histology, and the management of three cases are described. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1991.tb00805.x
更新日期:1991-02-01 00:00:00
abstract::This case report describes an approach to treatment for a patient with severe bone loss resulting from advanced periodontal diseae. A provisional splint was constructed in conjunction with suitable periodontal therapy. The purpose was to allow time for evaluation prior to deciding whether to commit the patient to perm...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1977.tb05117.x
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:Psychosomatic factors and their association with dermatological disorders are well recognized, yet their importance in oral lichen planus (OLP) is still debated. This study was done to determine the importance of psychosocial stressors in patients with OLP. METHODS:An analytical age-sex matched double contr...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2004.tb00072.x
更新日期:2004-12-01 00:00:00
abstract::A survey of over 2,000 second year high school students at 13 South Australian schools indicated that those who had received school dental care at primary school had fewer carious teeth and, in some respects, better oral hygiene habits. Whilst they were better informed on dental subjects than were control students, fe...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1976.tb02840.x
更新日期:1976-04-01 00:00:00
abstract:BACKGROUND:Previous studies by the authors have looked at the nature of the fissure system of human permanent molars and premolars, and has provided evidence for the presence of a prismless layer of enamel. It was noted during these studies that the fissure spaces were often occupied by material other than the fissure ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2003.tb00028.x
更新日期:2003-09-01 00:00:00
abstract::Heat-delivery devices have been associated with relatively high temperatures. Previous basic research studies suggest that the risk for periodontal tissues is negligible, as the presence of the root filling materials, amongst other factors, reduce the risk of overheating. This report describes the case of a 45 year ol...
journal_title:Australian dental journal
pub_type:
doi:10.1111/adj.12518
更新日期:2017-09-01 00:00:00
abstract::Most research on dental erosion has focused on erosion in enamel. However, the increasing retention of teeth into old age has increased the potential for root surface erosion. The nature and kinetics of root surface erosion have not yet been adequately explored. The objective of this project was to develop an in vitro...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2001.tb00283.x
更新日期:2001-09-01 00:00:00
abstract::The nature and the diagnosis and prognosis of the two forms of viral hepatitis is discussed. The possibility of transmission of these diseases during dental treatment to other patients or to dentists or their staff is considered and measures to reduce this risk are suggested. ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1977.tb05154.x
更新日期:1977-12-01 00:00:00
abstract::The oral consequences of opioid drug use are commonly attributed to personal neglect of general health and financial constraint. These factors are compounded by the increasingly recognized range of physical effects exerted by opioid drugs. The dental management of opioid drug dependents is further complicated by a var...
journal_title:Australian dental journal
pub_type: 杂志文章,评审
doi:10.1111/j.1834-7819.2002.tb00311.x
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Periodontal treatment may be a useful adjunct to medical management of diabetes; however, oral health has not been integrated into multidisciplinary diabetes care in Australia. This study aimed to understand the needs of patients and staff at a diabetes clinic to inform a prototype of integrated dental and d...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12804
更新日期:2020-11-06 00:00:00
abstract:BACKGROUND:This study tested the hypothesis that risk behaviours in disadvantaged groups would explain socio-economic inequality in dental caries prevalence among preschool children. METHODS:Using a case-control study, children with caries experience (one or more decayed, missing or filled primary tooth surfaces) and ...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.2006.tb00416.x
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:The current retrospective cross-sectional study investigated 5-18-year treatment outcomes in subjects who did not complete a recommended course of periodontal therapy. METHODS:Sixty-five subjects who voluntarily discontinued therapy were recalled. The subjects' demographic data and dental history since disc...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12440
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:There is evidence of a possible relationship between Archaea and periodontal disease; however, to date few studies have assessed the changes in prevalence of this domain after periodontal therapy. The aim of this randomized double-blind and placebo-controlled study was to assess if periodontal treatment with...
journal_title:Australian dental journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/adj.12123
更新日期:2013-12-01 00:00:00
abstract::At the commencement of the 1979 Academic Year a "modular approach" to degree studies in Dentistry will be instituted at the University of Papua New Guinea. This course of studies will be comprised of four progression modules and includes a one-year programme of community service and clinical experience in a dental cli...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1978.tb02396.x
更新日期:1978-10-01 00:00:00
abstract::Electromyographic analysis was carried out prior to occlusal equilibration for patients who had some form of TMJ dysfunction and again after treatment. The results were compared with similar analyses for patients without any symptoms of dysfunction (controls) and for patients who had been wearing some kind of occlusal...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/j.1834-7819.1978.tb03567.x
更新日期:1978-12-01 00:00:00
abstract:BACKGROUND:Dental caries and enamel defects (DDE) are prevalent amongst children. The presence of DDE, especially enamel hypomineralization, may increase caries experience. The reported prevalence of hypomineralized second primary molars (HSPM) is 2.7-21.8%, although the occurrence in Australian children remains unknow...
journal_title:Australian dental journal
pub_type: 杂志文章
doi:10.1111/adj.12567
更新日期:2018-03-01 00:00:00