Abstract:
:Cardiovascular morbidity and mortality remain frustratingly common in dialysis patients. A dearth of established evidence-based treatment calls for alternative therapeutic avenues to be embraced. Sympathetic hyperactivity, predominantly due to afferent nerve signaling from the diseased native kidneys, has been established to be prognostic in the dialysis population for over 15 years. Despite this, tangible therapeutic interventions have, to date, been unsuccessful and the outlook for patients remains poor. This narrative review summarizes established experimental and clinical data, highlighting recent developments, and proposes why interventions to ameliorate sympathetic hyperactivity may well be beneficial for this high-risk population.
journal_name
Semin Dialjournal_title
Seminars in dialysisauthors
Hoye NA,Wilson LC,Jardine DL,Walker RJdoi
10.1111/sdi.12756subject
Has Abstractpub_date
2019-05-01 00:00:00pages
255-265issue
3eissn
0894-0959issn
1525-139Xjournal_volume
32pub_type
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journal_title:Seminars in dialysis
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journal_title:Seminars in dialysis
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pub_type: 社论,指南,实务指引
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journal_title:Seminars in dialysis
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pub_type: 杂志文章
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journal_title:Seminars in dialysis
pub_type: 社论
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更新日期:2008-05-01 00:00:00
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pub_type: 社论,评审
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pub_type: 杂志文章,评审
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更新日期:2006-09-01 00:00:00
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journal_title:Seminars in dialysis
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