Abstract:
BACKGROUND:The current imbalance between donor supply and patients on the waiting list for liver transplantation (LT) is significant. To resolve this situation, marginal organs, such as those from type 2 donation after cardiac death (DCD2), are being considered. METHODS:In the present article, we present the first LT with a new protocol consisting in normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) for a type 2 DCD graft initially rejected for LT. RESULTS:After a favorable evolution with NMP (improved macroscopic appearance of the graft, acid-base equilibrium control and bile production), the transplantation was performed without major incidents. The evolution of the graft and patient were favorable. After 3 months, cholangiography showed no signs of ischemic cholangiopathy. CONCLUSIONS:Three-month patient and graft survival are encouraging, but more cases are needed to test the clinical efficacy of the new protocol.
journal_name
Cir Espjournal_title
Cirugia espanolaauthors
Pavel MC,Reyner E,Fuster J,Garcia-Valdecasas JCdoi
10.1016/j.ciresp.2018.06.016subject
Has Abstractpub_date
2018-10-01 00:00:00pages
508-513issue
8eissn
0009-739Xissn
1578-147Xpii
S0009-739X(18)30194-5journal_volume
96pub_type
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