Abstract：
:This study prospectively evaluated relationships between oral morbidities and swallowing ability in head/neck cancer patients following chemoradiation therapy (CRT) and at 3 months following CRT. Thirty patients with confirmed head/neck cancer undergoing chemoradiation were assessed with a battery of swallowing measures and measures of oral morbidities related to chemoradiation (xerostomia, mucositis, pain, taste/smell, oral moisture). All measures were completed at baseline (within the first week of CRT), at 6 weeks (end of treatment), and at 3 months following chemoradiation. Descriptive and univariate statistics were used to depict change over time in swallowing and each oral morbidity. Correlation analyses evaluated relationships between swallowing function and oral morbidities at each time point. Most measures demonstrated significant negative change at 6 weeks with incomplete recovery at 3 months. At 6 weeks, mucositis ratings, xerostomia, and retronasal smell intensity demonstrated significant inverse relationships with swallowing function. In addition, oral moisture levels demonstrated significant positive relationships with swallowing function. At 3 months, mucositis ratings maintained a significant, inverse relationship with swallow function. Taste and both orthonasal and retronasal smell intensity ratings demonstrated inverse relationships with measures of swallow function. Swallow functions and oral morbidities deteriorate significantly following CRT with incomplete recovery at 3 months post treatment. Furthermore, different patterns of relationships between swallow function measures and oral morbidities were obtained at the 6-week versus the 3-month assessment point suggesting that different mechanisms may contribute to the development versus the maintenance of dysphagia over the trajectory of treatment in these patients.
journal_name
Dysphagiajournal_title
Dysphagiaauthors
Ihara Y,Crary MA,Madhavan A,Gregorio DC,Im I,Ross SE,Carnaby GDdoi
10.1007/s00455-018-9895-6subject
Has Abstractpub_date
2018-12-01 00:00:00pages
739-748issue
6eissn
0179-051Xissn
1432-0460pii
10.1007/s00455-018-9895-6journal_volume
33pub_type
杂志文章相关文献
DYSPHAGIA文献大全abstract：:This pilot study examined the effect of a new head extension swallowing exercise (HESE) on submental muscle activity and tongue strength in healthy volunteers. Fifteen young adults (10 females and 5 males) were instructed to extend their head backwards as much as possible, and while watching the ceiling, swallowed the...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-016-9732-8
更新日期：2016-10-01 00:00:00
abstract：:The incidence of multiple swallows for liquid and paste, and the time delay between multiple swallows, was determined from videofluoroscopic records of modified barium swallow tests. In a comparison of liquid and paste, the overall incidence of multiple swallows did not differ, for either patients with head and neck c...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/BF02493415
更新日期：1992-01-01 00:00:00
abstract：:Although clinically evident aspiration is common in subjects with dysphagia, a significant proportion may aspirate silently, i.e., without any outward signs of swallowing difficulty. This article reviews the literature on the prevalence, etiology, and prognostic significance of silent aspiration. An electronic databas...
journal_title：Dysphagia
pub_type： 杂志文章,评审
doi：10.1007/s00455-005-0018-9
更新日期：2005-07-01 00:00:00
abstract：:The current classifications of dysphagia are based on local structural or central nervous system pathology causing dysfunction of the aerodigestive tract. The result is a clinical science grounded in the analysis of the swallow with its lingual, pharyngeal, and esophageal stages. Adding bolus preparation to the swallo...
journal_title：Dysphagia
pub_type： 杂志文章,评审
doi：10.1007/PL00009537
更新日期：1997-10-01 00:00:00
abstract：:Dysphagia is a potentially important symptom, often leading to the finding of an anatomical or motility disorder of the esophagus. Dysphagia and heartburn represent two of the most common symptoms associated with esophageal motility disorders. To explore the relationship of symptomatic esophageal dysphagia and heartbu...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/BF02412689
更新日期：1990-01-01 00:00:00
abstract：:Non-food gustatory stimulation has multiple potential therapeutic benefits for people with dysphagia and xerostomia. This study examined palatability and saliva flow associated with dissolvable flavored films. Taste strips with real-food flavors dissolved on the tongues of 21 persons with dysphagia and/or xerostomia a...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-018-9905-8
更新日期：2018-12-01 00:00:00
abstract：:Vomiting after feeding is a symptom of gastroesophageal reflux (GER) and of eosinophilic esophagitis (EE), which are considered to be a cause of infant feeding disorder. The objective of the present study was to evaluate swallowing in children with feeding disorder manifested by vomiting after feeding. Using clinical ...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-007-9122-3
更新日期：2008-06-01 00:00:00
abstract：:The purpose of this study was to describe the swallowing characteristics of elderly patients requiring mechanical ventilation with tracheostomy admitted to a long-term, acute-care hospital. The study was conducted through retrospective record review of patients on mechanical ventilation who had received a Modified Bar...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-003-0017-7
更新日期：2004-01-01 00:00:00
abstract：:Repetitive transcranial magnetic stimulation (rTMS) is one of the non-invasive techniques, which is used to modulate cortical regions in patients with stroke. The aim of this single blind, controlled study was to investigate the effect of rTMS on swallowing function and quality of life of mono-hemispheric post-stroke ...
journal_title：Dysphagia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00455-018-09965-6
更新日期：2019-06-01 00:00:00
abstract：:Videofluoroscopy has become an increasingly important armament in the investigation and assessment of swallowing disorders. However, very little work has been published on the radiation dose used in such examinations and currently there is no national diagnostic reference level in the United Kingdom. Videofluoroscopy ...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-006-9031-x
更新日期：2007-01-01 00:00:00
abstract：:A 36-year-old man who had sustained a closed head injury displayed extreme fear of being stimulated in the oral cavity, of being presented with foods, and of swallowing. The patient's fear increased his muscle tone and hypersensitivity in the facial and oral area, thereby preventing assessment of his dysphagia. We des...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/BF02493445
更新日期：1992-01-01 00:00:00
abstract：:Patient adherence to treatment recommendations is an important issue for healthcare providers, in a multitude of specialties, and is critical when assessing the efficacy and effectiveness of a particular treatment approach. Patients who have swallowing impairment often require complex and specific interventions requir...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-017-9852-9
更新日期：2018-04-01 00:00:00
abstract：:This article describes the results of a study that investigated how well wet phonation can predict penetration and/or aspiration of ingested material in dysphagic patients. Voice samples of 23 subjects with neurologic oropharyngeal dysphagia were collected immediately after each subject had swallowed nine different bo...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s004550010005
更新日期：2000-04-01 00:00:00
abstract：:This epidemiological investigation examined the prevalence, risk factors, and quality-of-life effects of swallowing disorders in Sjögren's syndrome (SS). One hundred and one individuals with primary or secondary SS (94 females, 7 males; mean age 59.4, SD = 14.1) were interviewed regarding the presence, nature, and imp...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-015-9657-7
更新日期：2016-02-01 00:00:00
abstract：:We tested the effect of effortful swallow combined with surface electrical stimulation used as a form of resistance training in post-stroke patients with dysphagia. Twenty post-stroke dysphagic patients were randomly divided into two groups: those who underwent effortful swallow with infrahyoid motor electrical stimul...
journal_title：Dysphagia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00455-012-9403-3
更新日期：2012-12-01 00:00:00
abstract：:Dysphagia is common following total laryngectomy. Postlaryngectomy neopharyngeal diverticulae are known to cause postlaryngectomy dysphagia but are more frequently asymptomatic. We report a case presenting with late-onset postlaryngectomy dysphagia and a suprastomal swelling secondary to such a diverticulum. The patie...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-004-0015-4
更新日期：2004-10-01 00:00:00
abstract：:Endoscopic dilatation is the recommended primary therapy for chronic corrosive esophageal strictures (ES), and surgery is reserved for failed dilatation. Through this study, we intend to analyze the efficacy and long-term outcomes of both endoscopic and surgical interventions in corrosive ES. A retrospective cohort an...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-019-10058-1
更新日期：2020-08-01 00:00:00
abstract：:The present study was designed to examine age and gender differences with respect to the duration of laryngeal closure, the onset of laryngeal closure in relation to the first cricopharyngeal opening, and the duration of cricopharyngeal opening for six different groups: normal younger men and women (22-29 years), norm...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-009-9257-5
更新日期：2010-12-01 00:00:00
abstract：:Cervical orthosis is used to immobilize the neck in various disorders such as trauma and post-operation. However, it is still uncertain how cervical orthosis restricts the degree of movement of the cervical spine during swallowing and how they affect swallowing physiology. The purpose of this study was to evaluate the...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-015-9660-z
更新日期：2016-02-01 00:00:00
abstract：:The influence of bolus volume and viscosity on the distribution of anterior lingual force during the oral stage of swallowing was investigated using a new force transducer technology. The maximum force amplitudes from 5 normal adults were measured simultaneously at the mid-anterior, right, and left lateral tongue marg...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/BF00417901
更新日期：1996-04-01 00:00:00
abstract：:Dysphagia is common after stroke. Neuromuscular electrical stimulation (NMES) and fiberoptic endoscopic evaluation of swallowing (FEES) for the treatment of dysphagia have gained in popularity, but the combined application of these promising modalities has rarely been studied. We aimed to evaluate whether combined NME...
journal_title：Dysphagia
pub_type： 临床试验,杂志文章
doi：10.1007/s00455-013-9466-9
更新日期：2013-12-01 00:00:00
abstract：:We measured the oral and pharyngeal transit of a paste bolus in 20 patients with Chagas' disease and 21 controls. Each subject swallowed of a 10-ml paste bolus prepared with 50 ml of water and 4.5 g of instant food thickener labeled with 55.5 MBq of 99m technetium phytate. After the scintigraphic recording of the tran...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-007-9101-8
更新日期：2008-03-01 00:00:00
abstract：:In individuals with Down syndrome, hypotonicity of the tongue and an underdeveloped maxilla may lead to poor oral motor coordination, which adversely affects the oral phase of swallowing. This study aimed to evaluate the characteristics of pressure produced by the tongue against the hard palate during swallowing in in...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-014-9538-5
更新日期：2014-08-01 00:00:00
abstract：:Yawning is a stereotyped motor behavior characterized by deep inhalation and associated dilation of the respiratory tract, pronounced jaw opening, and facial grimacing. The frequency of spontaneous yawning varies over the diurnal cycle, peaking after waking and before sleep. Yawning can also be elicited by seeing or h...
journal_title：Dysphagia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00455-014-9573-2
更新日期：2015-02-01 00:00:00
abstract：:Agreement between self-reported dysphagic symptoms and actual swallowing physiology can vary widely across individuals. The Eating Assessment Tool-10 (EAT-10) is a self-report questionnaire commonly used to identify individuals with oropharyngeal dysphagia, but its interpretation for highly prevalent populations is po...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-021-10244-0
更新日期：2021-01-24 00:00:00
abstract：:Functional dysphagia therapy (FDT) is a noninvasive procedure that can accompany percutaneous endoscopic gastrostomy (PEG) treatment and supports transitioning from tube to oral feeding. In this retrospective study, we investigated the outcome of FDT with or without PEG feeding. Patients with dysphagia were divided in...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-009-9270-8
更新日期：2011-06-01 00:00:00
abstract：:There have been a number of studies on the effect of bolus volume, consistency, texture, temperature and taste on the oropharyngeal swallowing physiology. However, its influence on the respiratory function associated with swallow is not well understood. This study aimed at systematically analysing and documenting the ...
journal_title：Dysphagia
pub_type： 杂志文章,评审
doi：10.1007/s00455-020-10103-4
更新日期：2020-12-01 00:00:00
abstract：:True vocal fold (TVF) dysfunction may lead to cough ineffectiveness. In individuals with motor neuron disease (MND), cough impairment in the context of dysphagia increases risk for aspiration and respiratory failure. This study characterizes differences and associations between TVF kinematics and airflow during cough ...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-014-9554-5
更新日期：2014-12-01 00:00:00
abstract：:The ability to measure normality and abnormality and to accurately assess true changes in swallowing function over time, is important for the management of dysphagia. Despite this, there is a paucity of information regarding the stability and reliability of measurements tools used for dysphagia research. As both head ...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-008-9181-0
更新日期：2009-06-01 00:00:00
abstract：:Dysphagia is a symptom suggestive of severe underlying pathology, although its causes include organic and non-organic disorders. The epidemiology of dysphagia is, however, poorly understood. We evaluated the prevalence of dysphagia in outpatients in Japan, measured the proportion ultimately found to have an organic ca...
journal_title：Dysphagia
pub_type： 杂志文章
doi：10.1007/s00455-016-9712-z
更新日期：2016-08-01 00:00:00
