CNV amplitude as a neural correlate for stuttering frequency: A case report of acquired stuttering.

Abstract:

:A neural hallmark of developmental stuttering is abnormal articulatory programming. One of the neurophysiological substrates of articulatory preparation is the contingent negative variation (CNV). Unfortunately, CNV tasks are rarely performed in persons who stutter and mainly focus on the effect of task variation rather than on interindividual variation in stutter related variables. However, variations in motor programming seem to be related to variation in stuttering frequency. The current study presents a case report of acquired stuttering following stroke and stroke related surgery in the left superior temporal gyrus. A speech related CNV task was administered at four points in time with differences in stuttering severity and frequency. Unexpectedly, CNV amplitudes at electrode sites approximating bilateral motor and left inferior frontal gyrus appeared to be inversely proportional to stuttering frequency. The higher the stuttering frequency, the lower the activity for articulatory preparation. Thus, the amount of disturbance in motor programming seems to determine stuttering frequency. At right frontal electrodes, a relative increase in CNV amplitude was seen at the test session with most severe stuttering. Right frontal overactivation is cautiously suggested to be a compensation strategy. In conclusion, late CNV amplitude elicited by a relatively simple speech task seems to be able to provide an objective, neural correlate of stuttering frequency. The present case report supports the hypothesis that motor preparation has an important role in stuttering.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Vanhoutte S,Van Borsel J,Cosyns M,Batens K,van Mierlo P,Hemelsoet D,Van Roost D,Corthals P,De Letter M,Santens P

doi

10.1016/j.neuropsychologia.2014.09.036

subject

Has Abstract

pub_date

2014-11-01 00:00:00

pages

349-59

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(14)00341-8

journal_volume

64

pub_type

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