Abstract：
:Polybrominated diphenyl ethers (PBDEs) may be metabolized to form hydroxylated and quinone products. Study on the formation of DNA adducts altered by PBDEs quinones was conducted. Various types of DNA adducts generated from in vitro reaction of deoxyguanosine (dG), 2'-deoxyadenosine (dA), 2'-deoxycytidine (dC), thymidine (T) and DNA with a PBDE-quinone metabolite, namely 2-(2',4'-bromophenoxyl)-benzoquinone (2'4'BrPhO-BQ) were characterized. The results suggest that the quinone compound could form various DNA adducts with dG, dA and dC via Michael Addition, which was confirmed from analyses by electrospray ionization tandem mass spectrometry. Two adducts were respectively generated from the reactions of 2'4'BrPhO-BQ with dC and dG, while three adducts were produced with dA. The formation of adducts of 2'4'BrPhO-BQ-deoxynucleoside changed with different pH of reaction solution. The obtained results demonstrated that 2'4'BrPhO-BQ could covalently bind to DNA mediated by quinone group. The in vitro data of the formation of DNA adducts might be valuable to elucidate the mechanism of interaction between PBDEs and DNA in vivo.
journal_name
Chemospherejournal_title
Chemosphereauthors
Huang L,Li C,Lai Y,Qiu B,Cai Zdoi
10.1016/j.chemosphere.2014.04.108subject
Has Abstractpub_date
2015-01-01 00:00:00pages
29-34eissn
0045-6535issn
1879-1298pii
S0045-6535(14)00632-8journal_volume
118pub_type
杂志文章相关文献
CHEMOSPHERE文献大全abstract：:Trace elements and heavy metals concentrate in aquatic sediments, potentially endangering benthic organisms. Comparing the concentration of metals in different aquatic bodies will help evaluate their accumulation and distribution characteristics within these systems. Metal pollution and enrichment indices in sediments...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.128243
更新日期：2021-01-01 00:00:00
abstract：:The European Union has defined environmental quality standards (EQSs) for surface waters for priority substances and several other pollutants. Furthermore national EQSs for several chemicals are valid in Austria. The study investigated the occurrence of these compounds in municipal wastewater treatment plant (WWTP) ef...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.01.033
更新日期：2012-06-01 00:00:00
abstract：:The characteristics of nitrous oxide, N2O, from a sewage treatment plant, which conducts nitrogen removal, and the river that receives its effluent water, were investigated by intensive daily surveys in summer and winter. N2O production in the sewage treatment plant was promoted in winter when nitrite accumulated in t...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.08.089
更新日期：2018-12-01 00:00:00
abstract：:The effects of chloridazon exposure at concentrations of 2.7 μg/L (maximal real environmental concentration in the Czech Republic), 27 μg/L, 135 μg/L and 270 μg/L on early life stages of marbled crayfish (Procambarus virginalis) were evaluated. Significantly higher glutathione S-transferase activity and reduced glutat...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127189
更新日期：2020-10-01 00:00:00
abstract：:Biochemical and genetic studies of xenobiotic metabolism in the model plant Arabidopsis have significant potential in providing information for phytoremediation. This paper presents the toxicity of 2,6-dinitrotoluene (2,6-DNT) to Arabidopsis under axenic conditions, the fate and transformation of 2,6-DNT after uptake ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2007.02.003
更新日期：2007-06-01 00:00:00
abstract：:Dose-dependent terathogenic effects of an organophosphate insecticide were found during early sea urchin development. This biological assay is low cost, easy to measure, and allows to detect the effects of the exposure of organisms to the active principle at concentrations lower than the acceptable daily intake (ADI) ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(98)00341-5
更新日期：1998-12-01 00:00:00
abstract：:Pot experiments were carried out to evaluate the response and intraspecific differences in nitrogen metabolism of 20 alfalfa cultivars under cadmium stress. To the aim, exogenous cadmium was added into soil with concentration of 0 (control) and 50 mg kg-1. Results showed that 20 alfalfa were ranked as following accord...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.12.101
更新日期：2019-04-01 00:00:00
abstract：:In a previous study it was shown that pH significantly influences the release of metals from oil sands coke, particularly Ni and V which were identified as the cause of coke leachate toxicity. Coke comes in contact with oil sands process water (OSPW) during its transport to and long term storage in reclamation landsca...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.10.018
更新日期：2012-02-01 00:00:00
abstract：:The MSWI fly ash (FA) is classified as hazardous waste and electrolytic manganese residue (EMR) as the harmful industrial waste. FA, water-washed FA (WFA), EMR and coal fly ash (CFA) were co-recycled to form lightweight MFCE ceramisites. The effects of FA, WFA and mixed MSWI fly ash on ceramisites were discussed. The ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127914
更新日期：2021-01-01 00:00:00
abstract：:The cationic surfactants cetyltrimethylammonium bromide (CTAB) and cetylpyridinium chloride (CPC) can exert inhibitory effects on micro-organisms responsible for their biodegradation. However, under environmentally relevant exposure scenarios the presence of and sorption to organic and inorganic matter can lead to sig...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.125643
更新日期：2020-04-01 00:00:00
abstract：:Waste-tire-derived crumb rubber was utilized as filter media to develop an efficient filter for ballast water treatment. In this study, the effects of coagulation, pressure filtration and dual-media (gravity) filtration on the performance of the crumb rubber filtration were investigated. The removal efficiencies of tu...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.11.048
更新日期：2009-03-01 00:00:00
abstract：:This study aimed to characterize PM2.5-bound trace elements in Northern Zhejiang Province (NZP), one of the most economically prosperous regions in China, and assess the associated health risks for the general populations. A year-long sampling campaign was conducted at four sites representative of urban, suburban, and...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2021.129632
更新日期：2021-01-13 00:00:00
abstract：:Sorption of 17alpha-ethinyl estradiol (EE2) and bisphenol A (BPA) by nonhydrolyzable carbon (NHC), black carbon (BC), and bulk soils and sediments was examined. All sorption isotherms were nonlinear and fitted both Freundlich and Dubinin-Ashtakhov (DA) models. The single-point organic carbon (OC)-normalized distributi...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2010.05.028
更新日期：2010-08-01 00:00:00
abstract：:In this study, the degradation kinetics of iopamidol (IPM) by three different UV-based oxidation processes including UV/hydrogen peroxide (H2O2), UV/persulfate (PDS) and UV/chlorine (NaClO) were examined and the potential formation of iodinated disinfection byproducts (I-DBPs) in these processes followed by sequential...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.12.162
更新日期：2019-04-01 00:00:00
abstract：:The effect of two terpenes, carvone and limonene, on the biodegradation of DELOR 103, a commercial mixture of polychlorinated biphenyls (PCBs), by Pseudomonas stutzeri, an isolate from long-term PCB-contaminated soil, was studied in detail. The addition of both carvone and limonene as potential inducers of the dioxyge...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(00)00523-3
更新日期：2001-09-01 00:00:00
abstract：:This study was aim to investigate the interaction between soil-derived dissolved organic matter (DOM) and atrazine as a kind of pesticides during the sorption process onto black soil. According to the experimental data, the adsorption capacity of Soil + DOM, Soil and DOM were 41.80, 31.45 and 9.35 mg kg-1, separately,...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.04.063
更新日期：2017-08-01 00:00:00
abstract：:Chlorinated ethenes (CE) are among the most common volatile organic compounds (VOC) that contaminate groundwater, currently representing a major source of pollution worldwide. Phytoscreening has been developed and employed through different applications at numerous sites, where it was generally useful for detection of...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.01.112
更新日期：2017-05-01 00:00:00
abstract：:In a historical mining area residual material has been filled on land and these locations are used today as agricultural soils or house gardens. The antimony concentrations in these soils are up to 500 mg/kg. Antimony transfer into 19 vegetable and crop species was investigated. In grain and other storage organs up to...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(00)00037-0
更新日期：2000-12-01 00:00:00
abstract：:Magnetic biochar was made from peanut hull biomass using iron chloride in a simplified aqueous phase approach and pyrolysis at alternative peak temperatures (450-650 °C). Magnetic biochar showed an extreme capacity for adsorption of hexavalent chromium Cr (VI) from aqueous solution, which was 1-2 orders of magnitude h...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2015.11.050
更新日期：2016-02-01 00:00:00
abstract：:In this report, the adsorption of Cr(VI) onto MnO2/CS nanocomposite material from aqueous solution is investigated. All the factors, which affect the adsorption, such as pH, adsorption time, Cr(VI) initial concentration and adsorbent dosage, are also examined. The results obtained show that the Cr(VI) uptake is strong...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127147
更新日期：2020-10-01 00:00:00
abstract：:Typically contained within ambient surface waters and certain industrial wastewaters, are plentiful halide ions, which possess varying degrees of photosensitivity. The effects of halide ions on the photodegradation of ibuprofen (IBP) were investigated under UV irradiation using a 500 W mercury lamp as a light source. ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.09.108
更新日期：2017-01-01 00:00:00
abstract：:Chlorpyrifos (O,O-diethyl O-3,5,6-trichloro-2 pyridyl phosphorothioate) 20 EC and Quinalphos (O,O-diethyl O-quinoxalin-2-yl phosphorothioate) 25 EC, were applied in groundnut (Arachis hypogaea L.) field as seed treatment at 25 ml/kg and soil treatment at 4 l/ha in 1998 and 1999. The residues of these insecticides were...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2005.07.053
更新日期：2006-05-01 00:00:00
abstract：:Polysaccharide-modified flocculant is a notable material in the field of wastewater treatment. Synthesis of biopolysaccharide derivatives as eco-friendly flocculants is remarkably desired for environmental protection. This work presents an efficient flocculant synthesized through copolymerization of acrylamide, sodium...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.06.010
更新日期：2016-09-01 00:00:00
abstract：:Rapid and sensitive monitoring of volatile organic compounds (VOCs) in aqueous samples is very important to human health and environmental protection. In this study, an on-line spray inlet proton transfer reaction mass spectrometry (SI-PTR-MS) method was developed for the rapid and sensitive monitoring of 6 different ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.02.141
更新日期：2017-06-01 00:00:00
abstract：:The octanol/water partition coefficient (Kow) for organic compounds is widely used in predictive environmental studies. A significant proportion of contaminants of surface and ground water are ionisable (e.g. many pesticides, pharmaceuticals, metabolites). Such compounds may be partially ionised dependent on the pH. S...
journal_title：Chemosphere
pub_type： 杂志文章,评审
doi：10.1016/j.chemosphere.2008.04.074
更新日期：2008-08-01 00:00:00
abstract：:Selenium can regulate arsenic toxicity by strengthening antioxidant potential, but the antagonism between selenite or selenate nutrient and the translocation of arsenic species from paddy soil to different rice organs are poorly understood. In this study, a pot experiment was designed to investigate the effect of sele...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.124712
更新日期：2020-01-01 00:00:00
abstract：:An unusual mortality event (UME) attributed to morbillivirus infection was identified in two Guiana dolphin populations from the Southeastern Brazilian coast. The aim of this study was to characterize total mercury (THg), methylmercury (MeHg) and selenium (Se) bioaccumulation and body burden in Guiana dolphins from Se...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.128286
更新日期：2021-01-01 00:00:00
abstract：:Within the rotational scheme developed by the Programme to fight the resistance of Simulium damnosum to chemical larvicides, there was an operational gap at discharges between 5 and 70 m3 s(-1) for the treatment of rivers where resistance to organophosphates was present. The use of permethrin and carbosulfan was precl...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(00)00172-7
更新日期：2001-03-01 00:00:00
abstract：:This study evaluates the impact of fluoxetine, an antidepressant drug and common pollutant in aquatic environments, on growth, survival, and behavior in juvenile guppies and on predator escape responses in adult guppies (Poecilia reticulata). In juveniles, the effects of acute (4d) and chronic (35d) exposure on growth...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2015.06.033
更新日期：2015-11-01 00:00:00
abstract：:Semi-domesticated reindeer and wild moose meat samples were analyzed for polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), and polychlorinated biphenyls (PCBs). Both calves and adults were studied. Individual reindeer and moose meat samples and pooled reindeer calf meat samples were collected from the nor...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2009.01.013
更新日期：2009-05-01 00:00:00
