Marginal decision-making in the treatment of refractory epilepsy.

abstract：OBJECTIVE:To compare the persistence and costs of brimonidine versus brinzolamide therapy according to data collected by the UK General Practitioner Research Database (GPRD). METHODS:Patients with diagnoses of ocular hypertension or glaucoma, or treated for glaucoma by surgery or laser therapy were identified. Selecte...

journal_title：Journal of medical economics

authors： Lafuma A,Laurendeau C,Berdeaux G

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To estimate direct medical costs and resource use for commercially-insured patients within two pulmonary hypertension sub-groups: pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). RESEARCH DESIGN AND METHODS:Using a retrospective cohort design, subjects (≥18 yea...

journal_title：Journal of medical economics

authors： Said Q,Martin BC,Joish VN,Kreilick C,Mathai SC

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the cost effectiveness (from a payer's perspective) of adding clostridial collagenase ointment (CCO) to selective debridement compared with selective debridement alone (non-CCO) in the treatment of stage IV pressure ulcers among patients identified from the US Wound ...

journal_title：Journal of medical economics

authors： Carter MJ,Gilligan AM,Waycaster CR,Schaum K,Fife CE

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Growing financial pressure on US dialysis providers requires economic efficiency considerations. The objective of this study was to examine short-term economic efficiencies of a cinacalcet-based treatment approach for secondary hyperparathyroidism. METHODS:This study retrospectively assessed cost per bioche...

journal_title：Journal of medical economics

authors： Belozeroff V,Lee A,Tseng S,Chiroli S,Campbell JD

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:This study evaluated the overall burden of illness of chemotherapy-induced nausea and vomiting (CINV) and associated all-cause costs from a hospital's perspective (costs to the hospital) in patients with cancer treated with chemotherapy (CT) in the US hospital outpatient setting. METHODS:Patients with a canc...

journal_title：Journal of medical economics

authors： Craver C,Gayle J,Balu S,Buchner D

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The ECHELON-1 trial demonstrated efficacy and safety of brentuximab vedotin plus doxorubicin, vinblastine, and dacarbazine (A + AVD) vs doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) as frontline therapy for stage III/IV classical Hodgkin lymphoma. This analysis evaluated the cost-effectiveness o...

journal_title：Journal of medical economics

authors： Delea TE,Sharma A,Grossman A,Eichten C,Fenton K,Josephson N,Richhariya A,Moskowitz AJ

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:Non-severe nocturnal hypoglycemic events (NSNHEs) may have a major impact on patients. The objective was to determine how NSNHEs affect diabetes management, sleep quality, functioning, and to assess if these impacts differ by diabetes type or country. METHODS:An internet survey to adults with diabetes in th...

journal_title：Journal of medical economics

authors： Brod M,Christensen T,Bushnell DM

更新日期：2012-01-01 00:00:00

abstract：AIMS:Hormonal imbalances can affect a woman's physical and mental condition, impacting her daily life and productivity. A mobile application, "Karada-no-kimochi", predicts the menstrual cycle based on recorded data, and provides the information regarding menstruation. This study investigates the effectiveness of the ap...

journal_title：Journal of medical economics

authors： Song M,Kanaoka H

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To assess patient characteristics, treatment patterns, and healthcare resource utilization (HRU)/costs of individuals treated for neuroendocrine tumors (NETs) in the US. METHODS:Using a US administrative claims database, this study identified commercially-insured adults newly diagnosed with carcinoid tumors ...

journal_title：Journal of medical economics

authors： Chuang CC,Bhurke S,Chen SY,Brulais S,Gabriel S

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Many countries have various requirements for local economic analyses to assess the value of a new health technology and/or to secure reimbursement. This study presents a case study of an economic model developed to assess the cost-effectiveness of posaconazole vs standard azole therapy (fluconazole/itraconaz...

journal_title：Journal of medical economics

authors： Papadopoulos G,Hunt S,Prasad M

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To investigate adherence to dornase alfa therapy among commercially-insured patients with cystic fibrosis (CF) and to examine the impact of adherence on health and economic outcomes. METHODS:This retrospective cohort analysis included CF patients with ≥1 dornase alfa (Pulmozyme) pharmacy claim between 1 Octo...

journal_title：Journal of medical economics

authors： Nasr SZ,Chou W,Villa KF,Chang E,Broder MS

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The spectrum of diseases caused by Streptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) represents a large burden on healthcare systems around the world. Meningitis, bacteraemia, community-acquired pneumonia (CAP), and acute otitis media (AOM) are vaccine-preventable infectious diseases tha...

journal_title：Journal of medical economics

authors： Knerer G,Ismaila A,Pearce D

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To compare outcomes between patients with type 2 diabetes mellitus (T2DM) using fixed-dose combination (FDC) and loose-dose combination (LDC) products. METHODS:This retrospective cohort study used MarketScan Commercial and Medicare Supplemental data from January 1, 2009-December 31, 2013. The identified popu...

journal_title：Journal of medical economics

authors： Lokhandwala T,Smith N,Sternhufvud C,Sörstadius E,Lee WC,Mukherjee J

更新日期：2016-01-01 00:00:00

abstract：AIM:Renal failure is a growing public health problem, and is mainly treated by hemodialysis. This study aims to estimate the societal costs of hemodialysis in Lebanon. METHODS:This was a quantitative, cross-sectional cost-of-illness study conducted alongside the Nutrition Education for Management of Osteodystrophy tri...

journal_title：Journal of medical economics

authors： Rizk R,Hiligsmann M,Karavetian M,Salameh P,Evers SM

更新日期：2016-12-01 00:00:00

abstract：:Aims: This study aimed to examine the long-term clinical and economic burden of adults with congenital heart disease (ACHD) in Hong Kong. Methods: It retrospectively analyzed 336 consecutive ACHD patients who attended the Adult Congenital Heart Clinic between January 1, 2009 and December 31, 2014. Direct medical costs...

journal_title：Journal of medical economics

authors： Lee VWY,Yan BP,Fong TMC,Fung AKP,Cheng FWT

更新日期：2019-08-01 00:00:00

abstract：AIMS:This paper evaluates the impact of multiple sclerosis (MS) in Ireland, and estimates the associated direct, indirect, and intangible costs to society based on a large nationally representative sample. MATERIALS AND METHODS:A questionnaire was developed to capture the demographics, disease characteristics, healthc...

journal_title：Journal of medical economics

authors： Carney P,O'Boyle D,Larkin A,McGuigan C,O'Rourke K

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To estimate the annualized differences in direct medical and indirect costs associated with improvement in fibromyalgia (FM) severity among pregabalin-treated patients. METHODS:Data from three clinical trials of pregabalin in patients with FM were modeled; efficacy results were extrapolated. Mean annual cost...

journal_title：Journal of medical economics

authors： Cappelleri JC,Bushmakin AG,Zlateva G,Chandran A

更新日期：2013-01-01 00:00:00

abstract：AIMS:Six Delta is a six-dimensional independent platform for outcome-based pricing/contracting. The six dimensions have been described separately: (δ1) cost-effectiveness analysis and cost-utility analysis-based pricing; (δ2) willingness-to-pay-based pricing; (δ3) reference-based pricing; (δ4) safety-based pricing; (δ5...

journal_title：Journal of medical economics

authors： Alkhatib NS,McBride A,Slack M,Bhattacharjee S,Erstad B,Ramos K,Abraham I

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:A new and smaller percutaneous ventricular assist device (pVAD, Impella, Abiomed, Danvers, MA) has been developed to provide circulatory support in hemodynamically unstable patients and to prevent hemodynamic collapse during high-risk percutaneous coronary interventions (PCI). The objective of the study was t...

journal_title：Journal of medical economics

authors： Roos JB,Doshi SN,Konorza T,Palacios I,Schreiber T,Borisenko OV,Henriques JP

更新日期：2013-01-01 00:00:00

abstract：:Aims: Nocturia (getting up at night to urinate, where each urination being followed by sleep or intention to sleep) is a bothersome symptom with potentially negative consequences for individual health and daytime functioning. This study assessed the burden of nocturia in the workplace by investigating associations bet...

journal_title：Journal of medical economics

authors： Hafner M,Andersson FL,Burtea T,van Stolk C,Whitmore M,Yerushalmi E,Troxel WM

更新日期：2020-09-01 00:00:00

abstract：AIMS:Percutaneous closure of a patent foramen ovale (PFO) is known to lower the risk of recurrent stroke in patients with a cryptogenic stroke. However, the economic implications of transcatheter PFO closure are less well known. From a UK payer perspective, a detailed economic appraisal of PFO closure was performed for...

journal_title：Journal of medical economics

authors： Hildick-Smith D,Turner M,Shaw L,Nakum M,Hartaigh BÓ,Evans RM,Rhodes JF,Sondergaard L,Kasner SE

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Abdominal paracentesis is commonly performed for diagnostic, therapeutic, and palliative indications, but the use of ultrasound guidance for these procedures is relatively recent, variable, and not well documented. A retrospective database analysis of abdominal paracentesis procedures was performed to determi...

journal_title：Journal of medical economics

authors： Patel PA,Ernst FR,Gunnarsson CL

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To critically evaluate published cost-effectiveness studies of novel drug products requiring less-frequent medication dosing compared to conventional formulations of the same drug substance. METHODS:A search was conducted in the Medline and Embase databases for cost-effectiveness studies published before May...

journal_title：Journal of medical economics

authors： Cheng MM,Alfonso R,Best JH,Garrison LP,Bruhn D,Veenstra DL

更新日期：2010-01-01 00:00:00

abstract：AIMS:In this pharmacoeconomic simulation, we: (1) modeled the cost-efficiency of converting patients from reference pegfilgrastim to biosimilar pegfilgrastim-cbqv for prophylaxis of chemotherapy-induced (febrile) neutropenia (CIN/FN) from the US payer perspective, (2) simulated how savings enable, on a budget-neutral b...

journal_title：Journal of medical economics

authors： MacDonald K,McBride A,Alrawashdh N,Abraham I

更新日期：2020-10-24 00:00:00

abstract：AIMS:Fast-acting insulin analogues (FAIAs) reduce hypoglycaemia and improve administration flexibility compared with short-acting human insulin (SHI). This analysis examines whether these benefits translate into cost offsets when comparing the total treatment costs for FAIA versus SHI used as basal-bolus therapy for tr...

journal_title：Journal of medical economics

authors： Christensen TE,Gundgaard J,Pilgaard T

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Reduction in health-related quality of life is common in children born small for gestational age (SGA) or children with growth hormone deficiency (GHD). Growth hormone treatment with somatropin in these children leads to normalisation of height. The aim of this study was to determine whether somatropin is a c...

journal_title：Journal of medical economics

authors： Christensen T,Fidler C,Bentley A,Djurhuus C

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Neuroblastoma (NB) is notorious in childhood cancer because of its high incidence and poor prognosis. The Children's Oncology Group reported that the 3-year OS in the high-risk (HR) group is 50%, and the HR-NB with bone marrow metastasis in our center is 43.1%. Thousands of families in China suffer from the ...

journal_title：Journal of medical economics

authors： Jiang C,Cai S,Duan C,Xu N,Zhou Y,Peng X,Ma X

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the economic burden of herpes zoster (HZ) on the US healthcare system among an immunocompetent population. METHODS:Claims data from the MarketScan Research databases for 2008-2011 were extracted to determine the incremental healthcare resource utilization (RU) and direct medical costs associated...

journal_title：Journal of medical economics

authors： Johnson BH,Palmer L,Gatwood J,Lenhart G,Kawai K,Acosta CJ

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:To compare demographic and comorbidity profiles and healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% (lidocaine patch) versus patients not treated with the lidocaine patch. Repeat comparison for the subset of patients treated in long-term care (LTC) sett...

journal_title：Journal of medical economics

authors： Kirson NY,Ivanova JI,Birnbaum HG,Wei R,Kantor E,Amy Puenpatom R,Ben-Joseph RH,Summers KH

更新日期：2010-01-01 00:00:00

abstract：:Objectives: Aging populations are contributing to an increased volume of osteoporotic fractures. The goals of this study were to (1) develop a scorecard on epidemiological burden, policy framework, service provision, and service uptake for osteoporosis in Saudi Arabia and (2) estimate the direct costs of managing oste...

journal_title：Journal of medical economics

authors： Aziziyeh R,Garcia Perlaza J,Saleem N,Sadat-Ali M,Elsalmawy A,McTavish RK,Duperrouzel C,Cameron C

更新日期：2020-07-01 00:00:00