Abstract:
BACKGROUND:A specific psychotherapy for chronic depression, the Cognitive Behavioral Analysis System of Psychotherapy (CBASP), was compared to escitalopram (ESC). METHODS:Sixty patients with chronic major depression were randomized to 'CBASP' (22 sessions) or 'ESC plus clinical management' (ESC/CM) at two treatment sites. The primary outcome measure was the score on the Montgomery-Asberg Depression Rating Scale (MADRS) after 8 weeks of acute treatment assessed by blinded raters. In the case of nonimprovement (<20% reduction in the MADRS score), the other condition was augmented for the following 20 weeks of extended treatment. Secondary end points were, among others, depressive symptoms, remission (MADRS score of ≤9) and response rates (reduction of MADRS score of ≥50%) 28 weeks after randomization. RESULTS:An intent-to-treat analysis revealed that clinician-rated depression scores decreased significantly after 8 and 28 weeks with no significant differences between the groups. The response rates after 28 weeks of treatment were high (CBASP: 68.4%, ESC/CM: 60.0%), and the remission rates were moderate (CBASP: 36.8%, ESC/CM: 50.0%) with neither group being superior. Nonimprovers to the initial treatment caught up with the initial improvers in terms of depression scores and response and remission rates by the end of the treatment after being augmented with the respective other condition. CONCLUSIONS:CBASP and ESC/CM appear to be equally effective treatment options for chronically depressed outpatients. For nonimprovers to the initial treatment, it is efficacious to augment with medication in the case of nonresponse to CBASP and vice versa.
journal_name
Psychother Psychosomjournal_title
Psychotherapy and psychosomaticsauthors
Schramm E,Zobel I,Schoepf D,Fangmeier T,Schnell K,Walter H,Drost S,Schmidt P,Brakemeier EL,Berger M,Normann Cdoi
10.1159/000381957subject
Has Abstractpub_date
2015-01-01 00:00:00pages
227-40issue
4eissn
0033-3190issn
1423-0348pii
000381957journal_volume
84pub_type
杂志文章,随机对照试验abstract::Some patients become grossly disorganized during a hospital stay for medical illness. In the midst of a confusing medical picture, the unpredictable behavior of such patients causes great consternation among the medical or surgical staff. Families also become particularly anxious; their concern about the medical probl...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000287284
更新日期:1978-01-01 00:00:00
abstract::The borderline has deficiencies in the capacity to maintain stable self and object representations and in establishing 'emotional separateness' from others. In order to create and maintain a 'propitious treatment situation' and a 'therapeutic alliance' the therapist must work with unusual sensitivity and repetitivenes...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000287017
更新日期:1976-01-01 00:00:00
abstract::Adolescents are frequently entangled in a web of transitions during their developmental journey from child to adult. These modulations include physiological and psychological changes: individual, familial and social readjustments, and alterations in the evolving family group. Psychosomatic manifestations are often tar...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000287421
更新日期:1980-01-01 00:00:00
abstract::The concept of the specificity of psychosomatic diseases (Alexander) is being differentiated at the time. In order to clarify some aspects of this problem, we want to investigate whether types of self-rating of normal persons differ from those of patients with bronchial asthma. In a second step we shall examine whethe...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288407
更新日期:1991-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章,随机对照试验
doi:10.1159/000481177
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:We explored whether medical health workers had more psychosocial problems than nonmedical health workers during the COVID-19 outbreak. METHODS:An online survey was run from February 19 to March 6, 2020; a total of 2,182 Chinese subjects participated. Mental health variables were assessed via the Insomnia Sev...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000507639
更新日期:2020-01-01 00:00:00
abstract::The impact of the loss of the breast in women undergoing surgical treatment for breast cancer is subordinated to the confrontation with the diagnosis of a malignancy in causing depression. The equal distribution of depression in mastectomy and in lumpectomy patients supports the hypothesis that it is the confrontation...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288153
更新日期:1989-01-01 00:00:00
abstract::In order to compare hypochondriacal phenomena in patients with generalized anxiety disorder (GAD) and panic disorder (PD), and in order to examine the relationship between worries about illness on one hand, and disease fears/phobias and hypochondriacal beliefs on the other, the authors administered the Illness Attitud...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288873
更新日期:1994-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000287738
更新日期:1983-01-01 00:00:00
abstract::Prevailing reports on psychological prediction of renal graft integration are rare, mostly based on case studies. Focusing on patients' expectations from the transplantation process before grafting, we investigate the influence of psychological data and statements on the final transplantation results. In the whole gro...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000287899
更新日期:1985-01-01 00:00:00
abstract::114 patients with permanent colostomy for carcinoma of the rectum were compared by questionnaire and interview with 110 cancer patients, having undergone colonic resection but not bearing a colostomy. The patients' own assessment of their health was for the colostomy group even better than for the controls. The emotio...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000286938
更新日期:1975-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章,meta分析
doi:10.1159/000343131
更新日期:2013-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288987
更新日期:1995-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 历史文章,杂志文章
doi:10.1159/000287311
更新日期:1979-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000289091
更新日期:1996-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288608
更新日期:1992-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288592
更新日期:1992-01-01 00:00:00
abstract::The relationship between depressed mood and alexithymia, measured by the Toronto Alexithymia Scale (TAS) was investigated in a group of psychiatric inpatients (n = 81) and outpatients (n = 97). In both cohorts correlations between the TAS and obsessoid personality style were significant when controlled for mood. The o...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288373
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Depressive syndromes that do not comply with the diagnostic criteria for specific depressive disorders are designated as 'subclinical' or 'subsyndromal' depressive syndromes. Using our own data from a clinical study, this paper outlines the significance of subclinical depressive syndromes and demonstrates th...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000012404
更新日期:2000-09-01 00:00:00
abstract::Endocrine and metabolic changes, as well as affective functions, were studied in eight healthy volunteers anticipating and executing a prearranged sequence of aerobatic flight. Control measurements were made at complete physical and mental rest. The following were determined: anxiety and hostility levels, blood glucos...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000286916
更新日期:1975-01-01 00:00:00
abstract::Metatherapy (a psychotherapeutic procedure based upon parental couple collaboration) is a technique useful for working with severely disorganized family contexts, in which psychopathological diseases (such as psychotic or psychosomatic disorders, suicide attempts of the children etc.) can appear. The management of the...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000288312
更新日期:1989-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000287297
更新日期:1978-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000162299
更新日期:2009-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000071897
更新日期:2003-09-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000287871
更新日期:1985-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Patients with medically unexplained symptoms (MUS) are difficult to treat and cause high health-care costs. Psychological interventions might be a beneficial option for treating patients with MUS, but evidence is inconsistent. This meta-analysis compares the effectiveness of psychological interventions for M...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000380914
更新日期:2015-01-01 00:00:00
abstract::Alexithymic characteristics were studied in 15 monozygotic and 18 like-sex dizygotic healthy young twin pairs in a semistructured interview. Variance analysis showed larger within-pair variances in the dizygotic than in the monozygotic twins. With some reservations, these results point to a genetic influence on the et...
journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章
doi:10.1159/000287301
更新日期:1978-01-01 00:00:00
abstract::From the moment Max Hamilton started his psychiatric education, he considered psychometrics to be a scientific discipline on a par with biochemistry or pharmacology in clinical research. His clinimetric skills were in operation in the 1950s when randomised clinical trials were established as the method for the evaluat...
journal_title:Psychotherapy and psychosomatics
pub_type: 传,历史文章,杂志文章
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更新日期:2009-01-01 00:00:00
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journal_title:Psychotherapy and psychosomatics
pub_type: 杂志文章,随机对照试验
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更新日期:2014-01-01 00:00:00