Abstract：
PURPOSE:Fluoride uptake of enamel after application of fluoride varnishes was compared with fluoride release into artificial saliva. The hypothesis was that fluoride uptake is higher for products exhibiting faster fluoride release. MATERIALS AND METHODS:Fluoride varnishes, i.e. Fluor Protector S, Duraphat, MI Varnish, Clinpro White Varnish, Profluorid Varnish and Enamel Pro Varnish were applied on bovine enamel specimens. Subsequently, specimens were incubated in artificial saliva. After removal of the varnishes, surface bound fluoride was extracted with potassium hydroxide and measured with an ion-selective electrode. Structurally bound fluoride was etched from the same specimens with perchloric acid. Fluoride release of varnish films into artificial saliva was measured for comparison. RESULTS:After 4 h in artificial saliva, the highest total enamel fluoride uptake of 47.9 μg F·cm-² was found with Fluor Protector S, followed by Enamel Pro Varnish with 22.1 μg F·cm-². The other products ranged between 12-16 μg F·cm-². This was several times higher than the negative control. Fluoride uptake did not correlate with release into artificial saliva. During the first 4 h, Duraphat released the lowest and MI Varnish the highest amount of fluoride with 7.7 and 249 μg F·cm-², respectively. The fluoride uptake of these two products was not statistically different. CONCLUSION:Enamel fluoride uptake cannot be predicted from the fluoride release rate of a product. Hence, based on the results of this study, fluoride release into artificial saliva is no measure for the efficacy of a fluoride varnish.
journal_name
Oral Health Prev Dentjournal_title
Oral health & preventive dentistryauthors
Bolis C,Härtli GP,Lendenmann Udoi
10.3290/j.ohpd.a34373subject
Has Abstractpub_date
2015-01-01 00:00:00pages
545-56issue
6eissn
1602-1622issn
1757-9996pii
34373journal_volume
13pub_type
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