Principles of plasticity in the developing brain.

Abstract:

:The developing brain is especially sensitive to a wide range of experiences, showing a remarkable capacity for plastic changes that influence behavioural outcomes throughout the lifetime. We review the principles that regulate this plasticity in development and consider the factors that modulate the developing brain. These include early sensory, motor, and language experience, early stress, caregiver interactions, peer interactions, psychoactive drugs, diet, microbiome, and the immune system. Emphasis is given to changes in behaviour, epigenetics, and neuronal morphology. WHAT THIS PAPER ADDS:A discussion of the surprising range of factors influencing brain development Life experiences interact resulting in a phenomenon called metaplasticity.

journal_name

Dev Med Child Neurol

authors

Kolb B,Harker A,Gibb R

doi

10.1111/dmcn.13546

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

1218-1223

issue

12

eissn

0012-1622

issn

1469-8749

journal_volume

59

pub_type

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