Abstract:
BACKGROUND:Structural and functional alterations occur in the caudate of patients with attention-deficit/hyperactivity disorder (ADHD). Here we aimed to investigate the functional connectivity between the dorsal caudate and other brain regions in ADHD children. METHODS:Resting-state functional connectivity from 30 ADHD and 33 age- and gender-matched "normal" children were measured by functional Magnetic Resonance Imaging. RESULTS:Positive connectivity with dorsal caudate was observed in the prefrontal areas, cingulate cortex and temporal lobe. Negative functional connectivity was observed in the precuneus, occipital cortices and cerebellum. The connectivity of left dorsal caudate to left inferior frontal gyrus was correlated with severity of ADHD. CONCLUSIONS:Connectivity of dorsal caudate with several brain regions was identified in ADHD children.
journal_name
Clin Imagingjournal_title
Clinical imagingauthors
Yang Z,Li H,Tu W,Wang S,Ren Y,Yi Y,Wu T,Jiang K,Shen H,Wu J,Dong Xdoi
10.1016/j.clinimag.2017.07.009subject
Has Abstractpub_date
2018-01-01 00:00:00pages
47-51eissn
0899-7071issn
1873-4499pii
S0899-7071(17)30129-8journal_volume
47pub_type
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