Temporary Intra-Operative Portocaval Shunts, Post-Operative Infections, and Mid-Term Survival after Cava-Sparing Liver Transplantation.

Abstract:

BACKGROUND:Temporary intra-operative portocaval shunts (TPCS) are believed to improve outcomes after cava-sparing liver transplantation. We hypothesize that decompression of the portal venous system via a TPCS reduces gut congestion, thereby decreasing bacterial translocation. Thus, we sought to clarify whether transplantation with a TPCS alters rates of post-operative infections and survival. PATIENTS AND METHODS:Patients undergoing liver transplantation (n = 189) were stratified by usage of a TPCS and the type of intra-operative antibiotic prophylaxis. Rates of post-operative infections were analyzed using the χ2 test. The log-rank test was used to compare 120-d survival. RESULTS:The analysis of patients transplanted with a TPCS and meropenem revealed increased infection rates with gut-specific pathogens (Escherichia coli, Escherichia faecalis, Escherichia faecium; p = 0.04) and equal 120-d survival in comparison with patients transplanted without a TPCS. When vancomycin was added to meropenem infection rates did not differ and patients transplanted with a TPCS had better survival in comparison with patients transplanted without a TPCS (p = 0.02). Within the TPCS group, the administration of meropenem and vancomycin was associated with improved survival in comparison with meropenem only (p = 0.03). CONCLUSION:Survival of patients may be improved by usage of a TPCS when gut-specific pathogens are covered by intra-operative antibiotic prophylaxis.

journal_name

Surg Infect (Larchmt)

journal_title

Surgical infections

authors

Weniger M,Andrassy J,Weig T,Grabein B,Crispin A,Rentsch M,Siebers C,Bazhin A,D'Haese JG,Hartwig W,Werner J,Guba M,Faist E,Pratschke S,Angele MK

doi

10.1089/sur.2017.036

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

803-809

issue

7

eissn

1096-2964

issn

1557-8674

journal_volume

18

pub_type

杂志文章
  • Right Colectomy and Abdominal Perineal Resection for Cancer: Do Urinary Tract Infections Impact Outcomes?

    abstract:BACKGROUND:We aim to assess the patient factors and concomitant infectious outcomes associated with urinary tract infection (UTI) occurrence and the impact of UTI on length of stay (LOS), re-admission, and death in a colorectal surgical population. PATIENTS AND METHODS:National Surgical Quality Improvement Program Use...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.282

    authors: Armstrong JG,Li CH,Liao J,Byrn JC

    更新日期:2017-07-01 00:00:00

  • Reflections on the Complexity of Surgical Site Infection Prevention and Detection from an Organizational Lens.

    abstract:: Background: Within the United States, surgical site infections (SSIs) have now become the most common hospital-acquired infection and impact 2%-5% of all surgical patients. It is estimated that approximately 60% of SSIs could be prevented through improved adherence to pre-...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.135

    authors: Collins CR,Wick EC

    更新日期:2019-10-01 00:00:00

  • Effect of Hand Antisepsis Agent Selection and Population Characteristics on Surgical Site Infection Pathogens.

    abstract:BACKGROUND:Selection of a pre-operative hand antisepsis agent has not been studied in relation to surgical site infection (SSI) culture data. In our hospital, we introduced an alcohol-based hand rub (ABR) in 2012 as an alternative to traditional aqueous surgical scrubs (TSS). It was the goal of this study to review any...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.125

    authors: Oriel BS,Chen Q,Wong K,Itani KMF

    更新日期:2017-05-01 00:00:00

  • Neonatal osteomyelitis and complex nephro-ureteral duplication.

    abstract:OBJECTIVE:This report presents a case of femoral osteomyelitis secondary to urinary tract infection in a female neonate with bilateral urinary duplication and right ectopic ureterocele. METHODS:A female neonate with a history of late perinatal sepsis presented to the emergency department and was found to have left dis...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2009.075

    authors: de Jesus LE,Fernandes A,Sias SM,de Mello CM,de Carvalho AM,Junior NC

    更新日期:2011-02-01 00:00:00

  • Clinical and economic consequences of post-operative infections following major elective surgery in U.S. hospitals.

    abstract:BACKGROUND:The incidence and consequences of post-operative infections in patients undergoing major elective surgery is not well understood. METHODS:Using a large U.S. healthcare claims database, we identified all patients who underwent major elective surgery between January 1, 2007, and December 31, 2009. For each su...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.200

    authors: Berger A,Edelsberg J,Yu H,Oster G

    更新日期:2014-06-01 00:00:00

  • Nasal carriage of Staphylococcus aureus among surgeons and surgical residents: a nationwide prevalence study.

    abstract:BACKGROUND:Staphylococcus aureus nasal carriage is an independent risk factor for developing nosocomial infections and for developing surgical site infection (SSI) in particular. The number of post-operative nosocomial S. aureus infections can be reduced by screening patients and decolonizing nasal carriers. In additio...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2014.022

    authors: van Vugt JL,Coelen RJ,van Dam DW,Winkens B,Derikx JP,Heddema ER,Stoot JH

    更新日期:2015-04-01 00:00:00

  • Defining the research agenda for surgical infection: a consensus of experts using the Delphi approach.

    abstract:BACKGROUND:A substantial proportion of operative procedures are complicated by infections, either remote from or related to the surgical site. These infections account for substantive morbidity and health care costs. With limited research funds available to study interventions designed to either prevent or reduce the m...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2006.7.101

    authors: Nathens AB,Cook CH,Machiedo G,Moore EE,Namias N,Nwariaku F

    更新日期:2006-04-01 00:00:00

  • Infective complications in laparoscopic surgery.

    abstract:BACKGROUND AND PURPOSE:One of the main benefits of minimally invasive surgery compared with open surgery is the significant reduction in the incidence of postoperative infections. Possible explanations include the smaller incision, minimal use of central venous catheters for parenteral nutrition, faster mobilization, r...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2006.7.s2-109

    authors: Boni L,Benevento A,Rovera F,Dionigi G,Di Giuseppe M,Bertoglio C,Dionigi R

    更新日期:2006-01-01 00:00:00

  • Surveillance of surgical site infection after cholecystectomy using the hospital in Europe link for infection control through surveillance protocol.

    abstract:BACKGROUND:The third most common healthcare-associated infection is surgical site infection (SSI), accounting for 14%-16% of infections. These SSIs are associated with high morbidity, numerous deaths, and greater cost. METHODS:A prospective study was conducted to assess the incidence of SSI in a single university hosp...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2012.096

    authors: Bogdanic B,Bosnjak Z,Budimir A,Augustin G,Milosevic M,Plecko V,Kalenic S,Fiolic Z,Vanek M

    更新日期:2013-06-01 00:00:00

  • Treating Surgical Infections in Low- and Middle-Income Countries: Source Control, Then What?

    abstract::Surgical infections present a significant burden of disease globally. Management focuses on source control and appropriate antibiotic therapy. This remains a challenge in low- and middle-income settings, where access to surgical care and antibiotics is limited. This paper discusses the complex challenges facing the ma...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2018.125

    authors: Rickard J

    更新日期:2019-04-01 00:00:00

  • Surgical infections with enterococcus: outcome in patients treated with ertapenem versus piperacillin-tazobactam.

    abstract:BACKGROUND:The pathogenicity of Enterococcus in polymicrobial surgical infections is controversial. The objective of this analysis was two-fold. The impact of Enterococcus on clinical outcome was assessed in adults with complicated intra-abdominal (IAI), complicated skin and skin structure (CSSSI), or acute pelvic (PI)...

    journal_title:Surgical infections

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1089/109629602762539553

    authors: Teppler H,McCarroll K,Gesser RM,Woods GL

    更新日期:2002-01-01 00:00:00

  • Validation and Performance Comparison of Two Scoring Systems Created Specifically to Predict the Risk of Deep Sternal Wound Infection after Bilateral Internal Thoracic Artery Grafting.

    abstract:: Background: The Gatti and the bilateral internal mammary artery (BIMA) scores were created to predict the risk of deep sternal wound infection (DSWI) after bilateral internal thoracic artery (BITA) grafting. Methods: Both score...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.252

    authors: Gatti G,Pappalardo A,Chocron S,Biondi F,Porcari A,Ceschia A,Luzzati R,Ecarnot F,Perrotti A

    更新日期:2020-06-01 00:00:00

  • The Surviving Sepsis Campaign: a history and a perspective.

    abstract:BACKGROUND:The Surviving Sepsis Campaign (SSC) was launched in 2002 as a collaborative initiative of the European Society of Intensive Care Medicine (ESICM), the International Sepsis Forum (ISF), and the Society of Critical Care Medicine (SCCM). Its objective was, through the development and promulgation of evidence-ba...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2010.024

    authors: Marshall JC,Dellinger RP,Levy M

    更新日期:2010-06-01 00:00:00

  • Active hexose correlated compound (AHCC) enhances resistance to infection in a mouse model of surgical wound infection.

    abstract:BACKGROUND:Infection is the most common postoperative complication within the surgical wound and during severe trauma. In spite of the use of modern sterile techniques and prophylaxis, infection continues to be a leading cause of death in these patients. Therefore, it has become crucial to develop new alternatives to p...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2006.7.527

    authors: Aviles H,O'Donnell P,Sun B,Sonnenfeld G

    更新日期:2006-12-01 00:00:00

  • Contemporary predictors of conversion from laparoscopic to open appendectomy.

    abstract:BACKGROUND:We defined the contemporary conversion rate from laparoscopic appendectomy (LA) to open appendectomy and identified pre-operative factors associated with conversion. METHODS:Retrospective review of 941 consecutive LAs performed for suspected acute appendicitis in a single urban university hospital between 2...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2010.079

    authors: Wagner PL,Eachempati SR,Aronova A,Hydo LJ,Pieracci FM,Bartholdi M,Umunna BP,Shou J,Barie PS

    更新日期:2011-08-01 00:00:00

  • Validation of a Predictive Scoring System for Deep Sternal Wound Infection after Bilateral Internal Thoracic Artery Grafting in a Cohort of French Patients.

    abstract:BACKGROUND:The Gatti score is a weighted scoring system based on risk factors for deep sternal wound infection (DSWI) that was created in an Italian center to predict DSWI risk after bilateral internal thoracic artery (BITA) grafting. No external evaluation based on validation samples derived from other surgical center...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.150

    authors: Perrotti A,Gatti G,Dorigo E,Sinagra G,Pappalardo A,Chocron S

    更新日期:2017-02-01 00:00:00

  • Use of Cidofovir for Cytomegalovirus Disease Refractory to Ganciclovir in Solid Organ Recipients.

    abstract:BACKGROUND:Solid organ transplantation (SOT) frequently is complicated by cytomegalovirus (CMV) infections. Cidofovir (CDV) is active against CMV, including many ganciclovir (GCV)-resistant mutants, but often is considered to be too nephrotoxic for use after organ transplantation. PATIENTS AND METHODS:Seven males and ...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2015.266

    authors: Bonatti H,Sifri CD,Larcher C,Schneeberger S,Kotton C,Geltner C

    更新日期:2017-02-01 00:00:00

  • Poor Outcome Could Be Predicted by Lower Monocyte Human Leukocyte Antigen-DR Expression in Patients with Complicated Intra-Abdominal Infections: A Review.

    abstract::Complicated intra-abdominal infections (cIAIs) are still associated with high morbidity and mortality levels. Early prognostic evaluation is a great challenge, and a serious amount of resources have been used to find the perfect mortality predictor. Monocyte human leukocyte antigen-DR (mHLA-DR) expression has been stu...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2019.050

    authors: Dimitrov E,Enchev E,Minkov G,Halacheva K,Yovtchev Y

    更新日期:2020-03-01 00:00:00

  • Antimicrobial Activity of Ceftaroline Tested against Staphylococcus aureus from Surgical Skin and Skin Structure Infections in US Medical Centers.

    abstract:BACKGROUND:Ceftaroline fosamil is a novel cephalosporin approved by the United States Food and Drug Administration (US FDA) for treatment of acute bacterial skin and skin structure infection, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). We evaluated the activity of ceftaroline and compa...

    journal_title:Surgical infections

    pub_type: 杂志文章,多中心研究

    doi:10.1089/sur.2015.209

    authors: Sader HS,Farrell DJ,Flamm RK,Jones RN

    更新日期:2016-08-01 00:00:00

  • Open fractures: it doesn't come out in the wash.

    abstract:BACKGROUND:Six hours from injury to washout is considered the gold standard in the treatment of open traumatic fractures. Despite this being our hospital policy, the rural nature of our Level I trauma center causes delays in discovery and transport, creating a unique randomization of time to washout. We hypothesized th...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2010.075

    authors: Schlitzkus LL,Goettler CE,Waibel BH,Sagraves SG,Hasty CC,Edwards M,Rotondo MF

    更新日期:2011-10-01 00:00:00

  • Polymorphonuclear neutrophil infiltration intensity as consequence of Entamoeba histolytica density in amebic colitis.

    abstract:BACKGROUND:It has been suggested that the damage observed in invasive amebiasis is related to interactions between polymorphonuclear leukocytes (PMN) and Entamoeba histolytica trophozoites. We analyzed the relation between infiltrating inflammatory cell populations and E. histolytica density in intestinal amebic lesion...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2008.011

    authors: Dickson-Gonzalez SM,de Uribe ML,Rodriguez-Morales AJ

    更新日期:2009-04-01 00:00:00

  • Severe group a streptococcus infection after thyroidectomy: report of three cases and review.

    abstract:BACKGROUND:Group A Streptococcus (GAS) is an uncommon cause of infection after clean surgery in non-pregnant adults. METHODS:Report of three cases and review of the literature. results: For the first time in France, severe GAS infections were observed in three patients who underwent thyroidectomy at three hospitals. T...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2007.069

    authors: Faibis F,Sapir D,Luis D,Laigneau P,Lepoutre A,Pospisil F,Borgey F,Demachy MC,Botterel F

    更新日期:2008-10-01 00:00:00

  • The Bacteremia Caused by Non-Lactose Fermenting Gram-Negative Bacilli in Solid Organ Transplant Recipients.

    abstract:BACKGROUND:Blood stream infections (BSIs) remain as a serious life-threatening condition after solid organ transplant (SOT). In recent years, a progressive growth in the incidence of bacteremia caused by non-lactose fermenting gram-negative bacilli (NLF GNB) has been observed. NLF GNB led to high mortality among SOT re...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2015.005

    authors: Wan Q,Ye Q,Huang F

    更新日期:2015-10-01 00:00:00

  • New antibiotic agents: problems and prospects.

    abstract:BACKGROUND:Surgical site infections are the third most common healthcare-associated infection, often leading to prolonged hospital stay and excessive expenditures. Management of these infections has become more challenging due to rising rates of multi-drug-resistant organisms and few new antibiotic options. METHODS:Th...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:

    authors: Weber DJ,Rutala WA

    更新日期:2005-01-01 00:00:00

  • Combined Strategy for Post-Operative Patients with Central Nervous System Infections Caused by Extensively Drug-Resistant/Pan-Drug-Resistant Acinetobacter baumannii: A Retrospective Study.

    abstract:: Background: Post-operative central nervous system infections (PCNSIs) caused by extensively drug-resistant (XDR) or pan-drug-resistant (PDR) Acinetobacter baumannii are rare but intractable problems. To investigate a potential combined strategy to treat Acinetobacter bauma...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.341

    authors: Chang JB,Chen Y,Wang H,Ma X,Zhang X,Wu H,Ma B,Zuo W,Ma W,Wang R,Wei J

    更新日期:2020-12-01 00:00:00

  • Successful treatment of Scedosporium aurantiacum osteomyelitis in an immunocompetent patient.

    abstract:BACKGROUND:Bacterial infections are a well-known complication of traumatic amputations. In cases involving contact with soil or water contaminated with manure, one also must be aware of infections with fungi, particularly Scedosporium spp. We report on an immunocompetent trauma patient with an infection caused by a rec...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2006.038

    authors: Kooijman CM,Kampinga GA,de Hoog GS,Goudswaard WB,Reijnen MM

    更新日期:2007-12-01 00:00:00

  • Safety of excisional inguinal lymph node biopsies performed for research purposes in HIV-1-infected women and men.

    abstract:BACKGROUND:Most HIV-1 replication occurs in secondary lymphoid tissues, and evaluating these tissues is crucial to investigations of pathogenesis. Inguinal lymph nodes (LN) are obtained frequently for these studies as they are readily detectable in most individuals and provide abundant numbers of cells. Knowledge of th...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.218

    authors: Meditz AL,Connick E,McCarter M

    更新日期:2014-08-01 00:00:00

  • Nosocomial infections adversely affect the outcomes of patients with serious intraabdominal infections.

    abstract:BACKGROUND:Patients with serious intraabdominal infections (IAI) who subsequently acquire nosocomial infections (NI) have been shown to have adverse outcomes. We evaluated factors that put patients at risk for developing NI and examined the effect of the NI on outcomes. METHODS:This study was a retrospective review of...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/109629604773860273

    authors: Merlino JI,Yowler CJ,Malangoni MA

    更新日期:2004-04-01 00:00:00

  • COVID-19 in Post-Operative Patients: Imaging Findings.

    abstract:: Background: Coronavirus 2019 (COVID-19) in the post-operative period is challenging. Its clinical manifestations may have similarities to other septic, thoracic, or gastrointestinal post-surgical complications. Additionally, the post-operative period may be a time of incre...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2020.169

    authors: Moliere S,Veillon F

    更新日期:2020-06-01 00:00:00

  • Surgery for appendicitis: is it necessary?

    abstract:BACKGROUND:Appendectomy for acute appendicitis is an effective, universally accepted procedure performed more than 300,000 times annually in the United States. It is generally believed that appendicitis progresses invariably from early inflammation to later gangrene and perforation, and that appendectomy is required fo...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2007.079

    authors: Mason RJ

    更新日期:2008-08-01 00:00:00