Abstract:
OBJECTIVE:The aim of this study was to determine the efficacy of short-duration use of finasteride and dutasteride before transurethral resection of the prostate (TURP) on intraoperative blood loss and microvessel density (MVD) of prostate stroma and suburethral tissues in benign prostatic hyperplasia (BPH). METHODS:This study includes 450 patients who were planned for TURP. They were prospectively randomized into three groups (150 patients each). Group 1 received placebo, group 2 received finasteride, 5 mg per day, and group 3 patients received dutasteride, 0.5 mg per day, for 4 weeks before surgery. The total blood loss, requirement of blood, and MVDs in prostate stroma and suburethral tissues were calculated in each patient and then compared among three groups. RESULTS:There was significant reduction in mean blood loss, blood loss/time, and total blood loss per gram of resected tissue in finasteride and dutasteride groups compared with placebo. Prostate stromal and suburethral MVDs were significantly higher compared with placebo. Blood transfusion was required in 9.3%, 2.7%, and 2% of the patients, respectively (p = 0.004). However, no statistically significant differences were observed between finasteride and dutasteride groups for these parameters (p > 0.05). The weight of resected prostate, operating time, and amount of irrigation fluid used did not show any significant difference between the three groups. CONCLUSION:Short-term pretreatment with finasteride and dutasteride has similar efficacy and significantly reduces perioperative bleeding during TURP and has minimal negative impact on sexual function. According to our findings, a 4-week prior administration of 5-alpha-reductase inhibitors may reduce operative blood loss and prostatic MVD in TURP, thus potentially decreasing blood loss-related complications and the requirement of blood transfusion.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Bansal A,Arora Adoi
10.1089/end.2016.0696-revsubject
Has Abstractpub_date
2017-09-01 00:00:00pages
910-917issue
9eissn
0892-7790issn
1557-900Xpii
10.1089/end.2016.0696-revjournal_volume
31pub_type
杂志文章,随机对照试验abstract:INTRODUCTION:Functional outcome and quality of life (QOL) domains are important outcomes after curative therapy for prostate cancer. Although useful for scientific purposes, QOL questionnaires may be too extensive for daily routine, and single questions or interview-assessed outcomes may be more practical alternatives....
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0735
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There remains equipoise with regard to whether laparoscopic radical prostatectomy (LRP) or robot-assisted radical prostatectomy (RARP) has any benefit over the other. Despite this, there is a trend for the increasing adoption of RARP at great cost to health services across the world. The aim was ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2014.0810
更新日期:2015-08-01 00:00:00
abstract::Laparoscopic living-donor nephrectomy has decreased the disincentives to live renal donation with a risk of complications similar to that of open donor nephrectomy. We report a patient who developed chylous ascites after an otherwise-uneventful laparoscopic donor nephrectomy. On MEDLINE search, we could find only two ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2005.19.839
更新日期:2005-09-01 00:00:00
abstract::A 42-year-old man undergoing bilateral laparoscopic hernia repair requested vasectomy for family planning purposes. Bilateral vasectomy was done by a laparoscopic approach at the time of extraperitoneal hernia repair, and a separate scrotal incision was avoided. In addition to reporting a case of laparoscopic vasectom...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/089277902753619618
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Laparoscopic radical cystectomy is confined to centers where advanced laparoscopy is performed, and its role is not yet well clear. Our aim was to evaluate, through a prospective comparative study, the advantages of the laparoscopic compared with an open approach. PATIENTS AND METHODS:From Novem...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2006.0224
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ascertaining the optimal depth of dilator progression is a crucial factor during tract dilation in percutaneous nephrolithotomy. Dilation is generally guided under fluoroscopy, ultrasonography, or combination of both techniques, and it is still difficult to prevent overdilation causing perforatio...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0710
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Patients with spinal neuropathy are at an increased risk for urolithiasis. Data on percutaneous nephrolithotomy (PCNL) in this population are limited. Our objective is to review our experience in managing stones with PCNL in patients with spinal neuropathy. PATIENTS AND METHODS:Twenty-one patien...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0344
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:We present our experience in the design and development of a training program in laparoscopic radical prostatectomy (LRP), and the validation of the first steps of the program by objective measurement of the attendants' skills improvement and subjective evaluation of its contents. MATERIALS AND METHODS:Our tra...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2014.0050
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:To construct, train, and apply an artificial neural network (ANN) system for prediction of different outcome variables of percutaneous nephrolithotomy (PCNL). We calculated predictive accuracy, sensitivity, and precision for each outcome variable. METHODS:During the study period, all adult patients who underwe...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0791
更新日期:2017-05-01 00:00:00
abstract::Ureteral injury is an uncommon complication of cesarean section. As with all iatrogenic ureteral injuries, if the problem is not recognized intraoperatively, the manifestations may be protean. The management of ureteral injury that is first recognized in the early postoperative period must be individualized. We presen...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1994.8.345
更新日期:1994-10-01 00:00:00
abstract::A case of a foreign body-induced renal stone in which the patient was treated successfully with a ureterorenoscopic approach is presented. ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1999.13.437
更新日期:1999-07-01 00:00:00
abstract::The surgical treatment of prostatic obstruction associated with a clinically significant bladder diverticulum has classically combined open diverticulectomy with relief of the bladder outlet obstruction. This report demonstrates that this result may be efficiently achieved by performing transurethral surgery followed ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1996.10.545
更新日期:1996-12-01 00:00:00
abstract::Cryoablation of renal masses is an evolving in situ ablative technique for the management of localized renal masses and can be performed in a laparoscopic or percutaneous manner. Its usefulness is increasing and correlates with the increasing frequency of incidentally diagnosed renal lesions. At present, this techniqu...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0102
更新日期:2008-06-01 00:00:00
abstract::In 2005 we reported in this journal the treatment of cystic nephroma, a rare but presumed benign renal tumor, with percutaneous resection. Initial follow-up confirmed removal of the intra-pelvic portion of the cystic nephroma and persistence of the unresected intra-parenchymal portion. Surveillance with computed tomog...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.0441
更新日期:2008-07-01 00:00:00
abstract::A trichobezoar with a calculus in the center was diagnosed in a young woman on long-term urethral catheter drainage. Urologists need to be aware of this potentially preventable complication to save patients from significant morbidity. ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/0892779041271562
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Tubercular cold abscess of the seminal vesicle is very rare, and only a few cases are reported in literature. Preoperative diagnosis is difficult and to the best of our knowledge has not been reported. CASE REPORT:A 35-year-old man presented with a 7-year history of blood in the semen and a reddish brownish...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.436
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Helical CT has become the preferred method for imaging urinary calculi, and so it would be useful if data from helical CT could also be used to predict the number of shockwaves (SWs) needed to break a given stone. METHODS AND MATERIALS:We measured the number of SWs required to comminute calcium ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2000.14.471
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVE:To determine whether or not temporary drainage is necessary immediately following laparoscopic (lap) and robot-assisted (rob) pyeloplasty (PP). PATIENTS AND METHODS:Of 99 patients undergoing lap PP (n = 23) or rob PP (n = 76) for treatment of ureteropelvic junction obstruction (UPJO), 52 had no drainage, 47 ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0655
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Nucleation, growth, and aggregation are considered to be the principal crystallization mechanisms in stone development. It is important to understand their relative significance so that appropriate experimental models can be used, and to identify the best therapeutic targets. The aim of this stud...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1999.13.605
更新日期:1999-11-01 00:00:00
abstract:PURPOSE:We describe a technique for safely accessing an upper pole calix through a 9th or 10th intercostal puncture. PATIENTS AND METHODS:A 9th or 10th intercostal access was used for percutaneous nephrolithotomy (PCNL) in nine patients. Thoracoscopy via the 5th or 6th intercostal space was used to ensure safe passage...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277901750426337
更新日期:2001-08-01 00:00:00
abstract:: Introduction: There has been a surge in robotic surgery research publications over the past 20 years. However, to date, there has been no characterization of urology's contribution to the robotic field, and there is a lack of bibliometric literature to guide future investi...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2018.0866
更新日期:2019-05-01 00:00:00
abstract::Growing data suggest that lymphadenectomy is a critical component of the surgical management of urologic malignancies with both diagnostic and therapeutic benefit. The increased use of minimally invasive approaches for the management of urologic malignancies may be in conflict with the need for more extensive lymphade...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.2009.0562
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Recent advances in endoscopy have enabled microscopic imaging of live bladdercancer cells in situ. The newly developed Endocystoscopy system (Olympus Medical Systems Co., Tokyo, Japan) is a flexible digital endoscope that has more than a 450-fold magnifying power on a video monitor. PATIENTS AND...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.698
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:We evaluated the feasibility and effectiveness of percutaneous urinary diversion in patients with obstructive uropathy. PATIENTS AND METHODS:A total of 206 percutaneous nephrostomies (PCNs) (right-sided in 54, left in 56, and bilateral in 48) were performed in 102 male and 57 female patients 18 to 94 years ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2000.14.401
更新日期:2000-06-01 00:00:00
abstract::Cold-knife retrograde endopyelotomy is a simple, safe, and effective therapeutic option for primary and secondary symptomatic ureteropelvic junction obstruction (UPJO). Our long-term success rate with negligible complications demonstrates its durability and safety. Retrograde endopyelotomy should be considered a viabl...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.9828
更新日期:2008-04-01 00:00:00
abstract::We herein present the first case in the literature of enucleation of an aldosterone-producing adenoma by laparoscopy. The indication for adrenal-sparing surgery was bilateral adrenal adenoma. The operation turned out to be easier than laparoscopic adrenalectomy. The postoperative course was uneventful, and the patient...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1997.11.145
更新日期:1997-04-01 00:00:00
abstract:PURPOSE:To estimate the acceptance rate of peer-reviewed journals, to describe the time course of subsequent full publication, and to identify those with characteristics associated with publication of the abstracts presented at the World Congress of Endourology (WCE). METHODS:All abstracts accepted for presentation at...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.996
更新日期:2006-12-01 00:00:00
abstract:INTRODUCTION:Drugs and their metabolites are known factors in 1% to 2% of all kidney stones. Certain antiepileptic drugs are known to cause stone formation. Phenytoin is used as a first line antiepileptic therapy for many seizure disorders. We present what we believe to be the first report of a phenytoin metabolite uri...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.0410
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To assess the long-term survival and prognostic factors in patients with renal-cell carcinoma (RCC) who were treated with radiofrequency ablation (RFA). PATIENTS AND METHODS:A retrospective review of the records of all patients who underwent RFA of biopsy-proven RCC from February 2006 to December 2010 was perf...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2015.0454
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To determine factors affecting patients' discomfort during the period self-retaining ureteral stents are in place. PATIENTS AND METHODS:Between April 2001 and May 2003, 58 male and 42 female patients underwent temporary double-pigtail stenting. The indications were endopyelotomy in 39 patients, ureteroscopy in...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.33
更新日期:2006-01-01 00:00:00