Endocytoscopy: novel endoscopic imaging technology for in-situ observation of bladder cancer cells.

Abstract:

BACKGROUND AND PURPOSE:Recent advances in endoscopy have enabled microscopic imaging of live bladdercancer cells in situ. The newly developed Endocystoscopy system (Olympus Medical Systems Co., Tokyo, Japan) is a flexible digital endoscope that has more than a 450-fold magnifying power on a video monitor. PATIENTS AND METHODS:This supermagnifying endoscope was used to evaluate bladder carcinoma in five patients through the working channel of a rigid cystoscope. RESULTS:The cell structure and nuclear morphology were imaged adequately compared with conventional hematoxylin and eosin staining of a biopsy specimen. The tumors were graded correctly in four of five cases. CONCLUSION:This novel technology appears to be useful for histologic diagnosis during endoscopic examinations, potentially allowing us to avoid a conventional biopsy.

journal_name

J Endourol

journal_title

Journal of endourology

authors

Ohigashi T,Kozakai N,Mizuno R,Miyajima A,Murai M

doi

10.1089/end.2006.20.698

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

698-701

issue

9

eissn

0892-7790

issn

1557-900X

journal_volume

20

pub_type

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