Abstract：
INTRODUCTION:Primary orbitofrontal cholesterol granuloma (OFCG) is rare. We present 4 cases of OFCG and a systematic literature review to examine patient characteristics, presentation, treatment, and outcome. METHODOLOGY:Our institutional records were reviewed for OFCG cases. A systematic literature review was performed using PubMed. Inclusion criteria were English-language studies with pathology-proven OFCG. Exclusion criteria were OFCG in a craniofacial sinus. The search-string yielded 172 results. Fifty studies met inclusion criteria (39 primary and 11 secondary), and relevant data were reviewed. RESULTS:Four patients underwent surgery for OFCG at our institution (ages 53, 43, 34, and 43; 3 females, 1 male). All patients were treated with surgery using a tailored frontal-orbital craniotomy with complete resection. There was no recurrence at 12-month, 4-year, 10-year, and 22-year follow-up for each patient, respectively. Systematic review of the literature identified 172 patients. Follow-up was available in 93 patients (54.1%) with a mean follow-up of 43.3 months. Seven patients demonstrated recurrence at a median of 36 months following surgery. Combining our 4 cases with the 93 patients with reported follow-up gives a recurrence rate of 7% (7/97). Recurrence was associated with incomplete resection and an orbital approach. CONCLUSION:Thorough removal of the lesion with curettage of the boney cavity is recommended for OFCG. Recurrence following complete removal of OFCG is rare.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Hughes JD,Jacob JT,Garrity JA,Salomao DR,Link MJdoi
10.1016/j.wneu.2015.11.095subject
Has Abstractpub_date
2016-03-01 00:00:00pages
355-61eissn
1878-8750issn
1878-8769pii
S1878-8750(15)01718-0journal_volume
87pub_type
杂志文章,评审abstract：BACKGROUND:There are no current evidence-based recommendations on mechanical thrombectomy (MT) in M2 or other distal occlusions. The objective of this paper was to investigate clinical and radiologic outcomes of MT in distal locations using the new generation of mini-0.017 microcatheter compatible-stent retrievers (SRs...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
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abstract：BACKGROUND:One of the main challenges during skull base tumor surgery is identifying the relationships between the lesion and the principal intracranial vessels. To this end, neuronavigation systems based on preoperative imaging lack accuracy because of brain shift and brain deformation. Intraoperative navigated B-mode...
journal_title：World neurosurgery
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/j.wneu.2017.07.052
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.05.072
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2013.01.093
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journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2017.11.156
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journal_title：World neurosurgery
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abstract：BACKGROUND:Microsurgical clipping is regarded as the most durable treatment for cerebral aneurysms. Aneurysm recurrence after clipping is uncommon and is associated with an increased risk of rupture. Reoperation for recurrent cerebral aneurysms is particularly challenging because of adhesions and scaring, and it carrie...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2016.06.065
更新日期：2016-09-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.04.005
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pub_type： 杂志文章,评审
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更新日期：2019-02-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2014.07.013
更新日期：2014-12-01 00:00:00
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pub_type： 杂志文章
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journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
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pub_type： 杂志文章
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2020-02-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：2016-10-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.wneu.2013.08.019
更新日期：2014-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-01-08 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2020-07-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.02.020
更新日期：2017-04-01 00:00:00
