An Omics Perspective on Candida Infections: Toward Next-Generation Diagnosis and Therapy.

Abstract:

:Candida species can cause severe infections associated with high morbidity and mortality. Therefore, it is essential to gain more insight into the anti-fungal host defense response. The advent of omics technology and development of advanced systems biology tools has permitted to approach this in an unbiased and quantitative manner. This review summarizes the insights gained on anti-Candida immunity from genetic-, transcriptome-, proteome-, metabolome-, microbiome-, mycobiome-, and computational systems biology studies and discusses practical aspects and future perspectives.

journal_name

Front Microbiol

authors

Smeekens SP,van de Veerdonk FL,Netea MG

doi

10.3389/fmicb.2016.00154

subject

Has Abstract

pub_date

2016-02-16 00:00:00

pages

154

issn

1664-302X

journal_volume

7

pub_type

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