Abstract:
:Congenital glioblastoma multiforme is a rare tumor of the central nervous system with unique features. The existing evidence on its pathogenesis, genetic and molecular profile, special characteristics, treatment, and prognosis is reviewed. An increased number of antenatal diagnoses and prolonged survival for those individuals who can tolerate combined surgical resection and chemotherapy has been noted. The overall prognosis, however, remains poor. A better understanding of this unusual entity is important. Further research is needed to discern tumor's pathogenesis and natural history. This will likely lead to the development and implementation of treatment strategies that may decrease mortality and morbidity in these patients.
journal_name
Neuropediatricsjournal_title
Neuropediatricsauthors
Anestis DM,Tsitsopoulos PP,Ble CA,Tsitouras V,Tsonidis CAdoi
10.1055/s-0037-1601858subject
Has Abstractpub_date
2017-12-01 00:00:00pages
403-412issue
6eissn
0174-304Xissn
1439-1899journal_volume
48pub_type
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