Evaluation of the corpus callosum in clumsy children born prematurely: a functional and morphological study.

Abstract:

:The aim of this study was to evaluate the incidence of functional and neuroradiological abnormalities of the corpus callosum in a group of 21 prematurely born children (GA < 34 weeks) who were found to be "clumsy" on the Movement Assessment Battery for Children at 6 years of age. All children underwent functional and morphological assessment of the corpus callosum. The functional assessment included tests of somesthesis, diadochokinesis and repetitive finger tapping. The morphology of the corpus callosum was evaluated on midsagittal MRI. Thirteen of the 21 clumsy children showed morphological abnormalities which were significantly associated with functional abnormalities. Morphological changes of the corpus callosum were also significantly associated with lesions on both neonatal ultrasound and late MRI. Our results support the view that morphological abnormalities of the corpus callosum are frequent in children born prematurely. The association between these abnormalities and lesions on US or MRI suggests that they are likely to be secondary to pre- or perinatal lesions.

journal_name

Neuropediatrics

journal_title

Neuropediatrics

authors

Mercuri E,Jongmans M,Henderson S,Pennock J,Chung YL,de Vries L,Dubowitz L

doi

10.1055/s-2007-973801

subject

Has Abstract

pub_date

1996-12-01 00:00:00

pages

317-22

issue

6

eissn

0174-304X

issn

1439-1899

journal_volume

27

pub_type

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