Preferential sites of metastatic relapse on MRI of initially localized ependymoma in children.

Abstract:

OBJECTIVE:Relapse of ependymoma in childhood portends a grave prognosis. While the detection of local recurrence is usually simple, spotting leptomeningeal metastasis might be challenging. We aimed to evaluate possible "hotspots" where metastasis tend to appear. MATERIALS AND METHODS:Medical records and Magnetic Resonance (MR) studies of all patients diagnosed with brain ependymomas between the years 2000-2015 were reviewed. RESULTS:Leptomeningeal spread was detected among 42% of relapsed patients. The most common sites were spine and hypothalamic area (26% each). CONCLUSION:A meticulous assessment of the brain and spine including a thorough evaluation of the hypothalamic area is recommended.

journal_name

Clin Imaging

journal_title

Clinical imaging

authors

Rootman MS,Konen O,Fried I,Toledano H

doi

10.1016/j.clinimag.2017.03.015

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

12-15

eissn

0899-7071

issn

1873-4499

pii

S0899-7071(17)30052-9

journal_volume

44

pub_type

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