Abstract：
PURPOSE:This study aimed to evaluate iron levels in cardiac and hepatic tissues using magnetic resonance imaging (MRI) T2*. METHODS:Cardiac and hepatic MRI was performed for 93 patients with β-thalassemia major. RESULTS:Cardiac T2* was in the range of 2.9-56.6 ms. Myocardial siderosis was detected in 44% of patients; 25 patients had moderate and severe siderosis with serum ferritin level (SFL) of 576-10,284 ng/ml. There was a significant correlation between SFL and cardiac T2* (p<.001). CONCLUSIONS:The effective role of MRI as a noninvasive producible method in measurement of iron concentration in tissues is not accessible with conventional techniques.
journal_name
Clin Imagingjournal_title
Clinical imagingauthors
Shamsian BS,Esfahani SA,Milani H,Akhlaghpoor S,Mojtahedzadeh S,Karimi A,Shamshiri AR,Alavi S,Safari A,Rezaei N,Arzanian MTdoi
10.1016/j.clinimag.2011.11.029subject
Has Abstractpub_date
2012-09-01 00:00:00pages
483-8issue
5eissn
0899-7071issn
1873-4499pii
S0899-7071(11)00309-3journal_volume
36pub_type
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