Evidence for Extending the Duration of Chemoprophylaxis following Free Flap Harvest from the Lower Extremity: Prospective Screening for Deep Venous Thrombosis.

Abstract:

BACKGROUND:The purpose of this study was to investigate the incidence of symptomatic and asymptomatic deep venous thrombosis in patients undergoing harvest of a free flap from the lower extremity who were receiving standard chemoprophylaxis while hospitalized. METHODS:A retrospective review of 65 consecutive patients undergoing surgery between 2011 and 2013 was performed to determine the incidence of symptomatic deep venous thrombosis. These patients were screened for deep venous thrombosis based on development of symptoms. Prospective evaluation of a similar consecutive population of 37 patients between 2014 and 2015 was then performed to determine the incidence of asymptomatic deep venous thrombosis. These patients underwent routine duplex ultrasonography of both legs at postoperative weeks 1 and 4. RESULTS:Symptomatic deep venous thrombosis occurred in 2.9 percent of all patients. In the prospective cohort, 8.1 percent of the patients were found to have an acute deep venous thrombosis by postoperative week 1. At postoperative week 4, 16.7 percent of the patients developed a new, acute deep venous thrombosis. The estimated costs of screening and treating deep venous thrombosis in the retrospective group and the prospective group were $222 and $2259, respectively. The cost of routine chemoprophylaxis without duplex screening for an additional 14 days after discharge was $125 per patient. CONCLUSIONS:The rate of asymptomatic deep venous thrombosis may be much higher than previously appreciated in this population of very high-risk patients, especially during the 2 weeks after discharge. Extending the duration of chemoprophylaxis to 4 weeks after surgery may be warranted. CLINICAL QUESTION/LEVEL OF EVIDENCE:Therapeutic, IV.

journal_name

Plast Reconstr Surg

authors

Rau AS,Harry BL,Leem TH,Song JI,Deleyiannis FW

doi

10.1097/PRS.0000000000002399

subject

Has Abstract

pub_date

2016-08-01 00:00:00

pages

500-508

issue

2

eissn

0032-1052

issn

1529-4242

pii

00006534-201608000-00040

journal_volume

138

pub_type

杂志文章
  • Airway and Feeding Outcomes of Mandibular Distraction, Tongue-Lip Adhesion, and Conservative Management in Pierre Robin Sequence: A Prospective Study.

    abstract:BACKGROUND:Pierre Robin sequence is characterized by mandibular retrognathia and glossoptosis resulting in airway obstruction and feeding difficulties. When conservative management fails, mandibular distraction osteogenesis or tongue-lip adhesion may be required to avoid tracheostomy. The authors' goal was to prospecti...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000003167

    authors: Khansa I,Hall C,Madhoun LL,Splaingard M,Baylis A,Kirschner RE,Pearson GD

    更新日期:2017-04-01 00:00:00

  • Various methods of breast reconstruction after mastectomy: an economic comparison.

    abstract::This study is an economic comparison of various methods of breast reconstruction after mastectomy. The hospital bills of 287 patients undergoing breast reconstruction at three institutions from June of 1988 to March of 1991 were analyzed. The procedures examined included mastectomy, implant and tissue-expander reconst...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199307000-00011

    authors: Elkowitz A,Colen S,Slavin S,Seibert J,Weinstein M,Shaw W

    更新日期:1993-07-01 00:00:00

  • Cranial fasciitis of childhood.

    abstract::Cranial fasciitis of childhood is a benign lesion occurring superficial to or involving the cranial bones of children at a median age of 18 months, with a male sex predilection of 2:1. It is histologically described as a well-circumscribed, loose proliferation of stellate to spindle-shaped fibroblasts in a myxoid back...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199004000-00018

    authors: Coates DB,Faught P,Sadove AM

    更新日期:1990-04-01 00:00:00

  • Shared medical appointments for preoperative evaluation of symptomatic macromastia.

    abstract:BACKGROUND:Shared medical appointments combine individual patient-physician encounters with a group educational segment. This allows for patients' needs to be addressed individually and for patients to benefit from shared learning. Shared medical appointments enhance knowledge, understanding, and management of disease ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000000750

    authors: Giladi AM,Brown DL,Alderman AK

    更新日期:2014-12-01 00:00:00

  • Stability of biodegradable implants in treatment of mandibular fractures.

    abstract:BACKGROUND:Biodegradable implants have not been used on a large scale for internal fixation of mandibular fractures because of presumed inferior mechanical properties. This prospective clinical trial was designed to elucidate the stability and biocompatibility of self-reinforced poly-L/D-lactide plates and screws used ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000165075.51898.6f

    authors: Yerit KC,Hainich S,Turhani D,Klug C,Wittwer G,Ockher M,Ploder O,Undt G,Baumann A,Ewers R

    更新日期:2005-06-01 00:00:00

  • Functional return of tendon graft protected entirely by pseudosheath--experimental study.

    abstract::Sixty-three white Leghorn chickens were used in a two-stage tendon grafting into the deep flexor of the third toe. In the first stage, a 4- or 8-week-old pseudosheath was created around the Silastic rod. In the second stage, the grafting was carried out: in 33 birds the new sheath covered the entire tendon graft and i...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198002000-00011

    authors: Farkas LG,Lindsay WK

    更新日期:1980-02-01 00:00:00

  • The history of injectable silicone fluids for soft-tissue augmentation.

    abstract:BACKGROUND:The debate over the legitimacy of silicone as a safe tool for soft-tissue augmentation has spanned well over half a century. Proponents concede that injections of questionable purity and/or of massive quantities have produced unfavorable outcomes. They assert that in experienced hands with "injectable-grade"...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/01.prs.0000267580.92163.33

    authors: Chasan PE

    更新日期:2007-12-01 00:00:00

  • The Current Role of Three-Dimensional (3D) Printing in Plastic Surgery.

    abstract::Since the advent of three-dimensional (3D) printing in the 1980s, it is now possible to produce physical objects from digital files and create 3D objects by adding one layer at a time following a predetermined pattern. Due to the continued development of inexpensive and easy- to- use 3D printers and bioprinting, this ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000000150

    authors: Kamali P,Dean D,Skoracki R,Koolen PG,Paul MA,Ibrahim AM,Lin SJ

    更新日期:2016-01-21 00:00:00

  • Bioactive sutures.

    abstract::With the first wave of bioactive sutures already in the marketplace, research is ongoing in the development of future products. Such sutures could potentially have not only antimicrobial activity but also anesthetic and antineoplastic functions. Some clinical trials have already been completed in Russia. This technolo...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/01.prs.0000248418.23513.1f

    authors: Neligan PC,Plastic Surgery Educational Foundation Technology Assessment Committee.

    更新日期:2006-12-01 00:00:00

  • Skin flap failure: pathophysiology.

    abstract::An experimental study was undertaken in pigs to clarify the pathophysiologic events occurring in a failing skin flap. It was demonstrated that skin flaps fail because of arterial insufficiency. Arteriovenous shunting is not a major cause of skin flap necrosis. ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-198312000-00003

    authors: Kerrigan CL

    更新日期:1983-12-01 00:00:00

  • Vascular Endothelial Growth Factor Enhances Proliferation of Human Tenocytes and Promotes Tenogenic Gene Expression.

    abstract:BACKGROUND:In obtaining human tenocytes for tendon tissue engineering, a low proliferation rate and phenotype loss during passaging is a problem. It was the authors' aim to evaluate the influence of vascular endothelial growth factor (VEGF) on human tenocyte growth and gene expression. METHODS:Human tenocytes were exp...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000004920

    authors: Kraus A,Sattler D,Wehland M,Luetzenberg R,Abuagela N,Infanger M

    更新日期:2018-11-01 00:00:00

  • The American Association of Plastic Surgeons Recent History, with a Review of the Past.

    abstract::The American Association of Plastic Surgeons was founded in 1921 and is the oldest of the plastic surgery societies. It was born out of the enthusiasm of reconstructive surgeons who had recently increased in numbers and expanded the scope of their activities as a result of the challenges posed by battle-injured soldie...

    journal_title:Plastic and reconstructive surgery

    pub_type: 历史文章,杂志文章

    doi:10.1097/PRS.0000000000002259

    authors: Lawrence WT

    更新日期:2016-07-01 00:00:00

  • Reduction mammaplasty and correction of ptosis: a personal technique.

    abstract::New upper pedicle reduction mammaplasty and mastopexy techniques are presented. The surgical steps are described point by point. An analysis is made of the results obtained in 25 patients who underwent surgery between November of 1987 and November of 1988 and were examined in December of 1990 with a mean follow-up of ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199305000-00012

    authors: Marconi F,Cavina C

    更新日期:1993-05-01 00:00:00

  • In vitro deflation of prefilled saline breast implants.

    abstract:BACKGROUND:The purpose of this study was to determine whether or not prefilled breast implants retain their volume in packaging. METHODS:This study examined 32 Poly Implant Prosthesis prefilled textured saline breast implants. All of these implants were within the manufacturer's expiration date at the time of weighing...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000227674.65284.80

    authors: Stevens WG,Hirsch EM,Stoker DA,Cohen R

    更新日期:2006-08-01 00:00:00

  • Determining the Oncologic Safety of Autologous Fat Grafting as a Reconstructive Modality: An Institutional Review of Breast Cancer Recurrence Rates and Surgical Outcomes.

    abstract:BACKGROUND:The increasing use of autologous fat grafting in breast cancer patients has raised concerns regarding its oncologic safety. This study evaluated patient outcomes and tumor recurrence following mastectomy reconstruction and autologous fat grafting. METHODS:Retrospective chart review identified patients who u...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0000000000003576

    authors: Cohen O,Lam G,Karp N,Choi M

    更新日期:2017-09-01 00:00:00

  • Facial asymmetry: three-dimensional analysis using laser surface scanning.

    abstract::This study evaluates six different techniques with respect to their ability to quantitatively describe facial asymmetry in three dimensions. Three-dimensional facial images were acquired using a Cyberware 3030RGB laser surface scanner. Image processing was performed on a Silicon Graphics Indigo computer workstation. T...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199909040-00006

    authors: O'Grady KF,Antonyshyn OM

    更新日期:1999-09-01 00:00:00

  • Histologic structure of human costochondral junction.

    abstract::Costochondral grafts are commonly used to restore dysplastic mandibular condyles. Despite their worldwide use, the growth of the condyle-ramus unit constructed with a costochondral graft is highly unpredictable, excess growth being the most common consequential problem. In a recent series of experiments on rats, it be...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199410000-00003

    authors: Peltomäki T

    更新日期:1994-10-01 00:00:00

  • Free flap from the flexor aspect of the wrist for resurfacing defects of the hand and fingers.

    abstract::The distal portion of the flexor aspect of the forearm has been used as the donor site of full-thickness skin grafts, venous skin grafts, and Chinese forearm flaps. This article describes the use of a free flap harvested from the flexor aspect of the wrist and based on the superficial palmar branch of the radial arter...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.PRS.0000049883.75820.4F

    authors: Sakai S

    更新日期:2003-04-01 00:00:00

  • The Future of Plastic Surgery Resident Education.

    abstract::The challenge of the current graduate medical education environment requires in plastic surgery acceptance of those contemporary pressures that cannot be substantially modified and address of those that can be successfully met. To do so implies an examination of conference didactics, intraoperative teaching, and a val...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/01.prs.0000479982.67922.8a

    authors: Luce EA

    更新日期:2016-03-01 00:00:00

  • Macroscopic and microangiographic anatomy of the teres major muscle: a new free functional muscle flap?

    abstract:BACKGROUND:The teres major can be seen as an additional head of the latissimus dorsi muscle for three-dimensional movement of the arm. It gained importance in pedicled muscle transfers for the treatment of plexus palsies and shoulder instability. Its supplying vessels belong to the subscapular system. According to the ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/01.prs.0000252268.06443.61

    authors: Giessler GA,Doll S,Germann G

    更新日期:2007-03-01 00:00:00

  • Analysis of nerve and neuropeptide patterns in vacuum-assisted closure-treated diabetic murine wounds.

    abstract:BACKGROUND:Reestablishment of the peripheral nervous system occurs in parallel with wound healing. With accelerated wound healing seen with the vacuum-assisted closure device, the authors studied its effects on nerve fiber regeneration, nerve sprouting, and the stimulation of neuropeptides and neurotrophins. METHODS:A...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e3181da86d0

    authors: Younan G,Ogawa R,Ramirez M,Helm D,Dastouri P,Orgill DP

    更新日期:2010-07-01 00:00:00

  • Ernst Blasius's contributions to plastic surgery.

    abstract::Blasius was a famous teacher and surgeon. Apart from his own writings on surgery and his new methods for reconstructions, such as the replacement of nose, lips, and eyelids, some theses were also inspired by him. His main work is his three-volume Handbuch der Akiurgie, to which he added an excellent atlas, from which ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1097/00006534-198410000-00020

    authors: Hauben DJ

    更新日期:1984-10-01 00:00:00

  • The intravascular stenting method for treatment of extremity lymphedema with multiconfiguration lymphaticovenous anastomoses.

    abstract:BACKGROUND:In secondary extremity lymphedema, normal antegrade lymphatic flow is disrupted by the disease state. Attempts to capture aberrant retrograde lymphatic flow by means of microsurgical lymphaticovenous anastomoses have been hindered because of technical limitations. The authors applied the intravascular stenti...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e3181cb64da

    authors: Narushima M,Mihara M,Yamamoto Y,Iida T,Koshima I,Mundinger GS

    更新日期:2010-03-01 00:00:00

  • Neuromucosal prelaminated flaps for reconstruction of intraoral lining defects after radical tumor resection.

    abstract::To reconstruct intraoral lining defects after radical tumor resection by reinnervated vascularized mucosa, eight distal radial forearm flaps and two fibula flaps were prelaminated. Prelamination was performed by exposing the vascularized fascia, onto which the split distal end of a sural graft was fixed. The fascia an...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199903000-00007

    authors: Rath T,Tairych GV,Frey M,Lang S,Millesi W,Glaser C

    更新日期:1999-03-01 00:00:00

  • Microsurgical lymphaticovenous implantation for the treatment of chronic lymphedema.

    abstract::This article presents our experience with microsurgical lymphaticovenous implantation in the treatment of chronic lymphedema. Our attempt is to create a lymphaticovenous shunt with an implantation of the collecting lymphatics, including some lymphatic vessels and lymphatic capillaries, within external connective adven...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199801000-00026

    authors: Yamamoto Y,Sugihara T

    更新日期:1998-01-01 00:00:00

  • The importance of a skin bridge in peripheral tissue perfusion in perforator flaps.

    abstract:BACKGROUND:Perforator flaps are increasingly used in reconstructive surgery. However, the microvascular perfusion pattern within these flaps remains essentially unknown. In perforator flaps, the importance of preserving the skin bridge at the base is still an object of debate. The authors hypothesized that dividing the...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/PRS.0b013e31824423f8

    authors: Mešić H,Kirkebøen KA,Bains R

    更新日期:2012-03-01 00:00:00

  • A systematic review of comparison of efficacy and complication rates among face-lift techniques.

    abstract:BACKGROUND:The ideal face lift has the longest efficacy, the fewest complications, and ultimately, the highest patient satisfaction. With so many different techniques, there exists a need to make this comparison and to establish which approaches may work best in various groups. To date, there has been no systematic rev...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审

    doi:10.1097/PRS.0b013e3181f95c08

    authors: Chang S,Pusic A,Rohrich RJ

    更新日期:2011-01-01 00:00:00

  • Neurovascular free flaps. A preliminary report.

    abstract::An experimental, anatomical, and clinical study has confirmed the feasibility of free neurovascular flaps. The interrelationship between the cutaneous vascular and neural supply has been defined and demonstrated electrophysiologically, both in man and in experimental animals. A potential donor site in man has been e...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-197507000-00004

    authors: Daniel RK,Terzis J,Schwarz G

    更新日期:1975-07-01 00:00:00

  • Platysma muscle cutaneous flap for large defects of the lower lip and mental region.

    abstract::Based on the experience acquired using the depressor anguli oris flap for lateral lower lip reconstruction, the authors in this paper present their own technique to reconstruct large deficits of the lower lateral lip, involving the commissure and the mental region, by means of a platysma muscle cutaneous flap with a t...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199806000-00005

    authors: Moschella F,Cordova A

    更新日期:1998-06-01 00:00:00

  • Tissue expansion in the treatment of pressure ulcers.

    abstract::The authors report their experience using skin expanders in 11 patients with severe bed sores. The expanders, with different volumes, from 250 to 1000 cc, were generally overfilled using the cutaneous tonometer. In fact, with the information revealed by this apparatus on the skin in expansion, the authors were able to...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章

    doi:10.1097/00006534-199103000-00018

    authors: Esposito G,Di Caprio G,Ziccardi P,Scuderi N

    更新日期:1991-03-01 00:00:00