Abstract：
BACKGROUND:Multiple sclerosis (MS) is a common autoimmune and neurodegenerative disease of the central nervous system characterized by inflammatory demyelination, axonal degeneration, and neuronal loss. The exact pathogenesis of MS remains uncertain; however, studies have shown that the development of MS is influenced by genetic and environmental factors. Cerebral aneurysms (CAs) are life-threatening lesions of cerebral vessels characterized by a bulge in the intracranial arterial wall that spontaneously ruptures. It has been hypothesized that patients with MS are at increased risk of developing cerebral aneurysms. This hypothesis can be supported by analyzing the pathogenesis and genetics of the development of MS and CA. To our knowledge, no previous studies have shown an association between MS and CA. CASE DESCRIPTION:In this report, we performed middle cerebral artery aneurysm clipping for two patients with MS who were referred to our clinic for CA in the bifurcation of middle cerebral artery that was found incidentally on magnetic resonance imaging. We aim to identify any genetic correlation between MS and CA pathogenesis. CONCLUSION:This report suggests a possible genetic association between MS and CAs. The strongest evidence of association was found for the TNFRSF1A gene, a proinflammatory gene that is involved in mitogen-activated protein kinase (MAPK) and NF-Kappa B signaling pathways, and has been identified as a candidate gene in the development of MS. MAPKs were also found to be elevated in CAs.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Albrekkan FM,Bachir S,Jumaa MA,Zaidi SF,Medhkour Adoi
10.1016/j.wneu.2016.04.027subject
Has Abstractpub_date
2016-11-01 00:00:00pages
624.e1-624.e4eissn
1878-8750issn
1878-8769pii
S1878-8750(16)30151-6journal_volume
95pub_type
杂志文章abstract：BACKGROUND:We describe our experience in the endoscopic treatment of cervical spondylosis. We present a "hybrid" technique that is similar to an open anterior cervical discectomy with fusion but is performed endoscopically. We also analyzed data from studies on endoscopic cervical discectomies published in the past 2 d...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.wneu.2019.07.122
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Neuronavigation has become a common means of placing pedicle screws in vertebral arthrodesis, because it reduces the incidence of complications related to poor screw positioning. OBJECTIVE:The To evaluate the accuracy of pedicle screw placement during lumbar arthrodesis performed with the new ROSA Spine rob...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.05.118
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:Interbody cage implantation during minimally invasive surgery for transforaminal lumbar interbody fusion (MIS TLIF) presents challenges. Expandable cages when collapsed facilitate insertion; subsequent expansion in situ optimizes endplate contact. This report describes clinical and radiographic outcomes of MI...
journal_title：World neurosurgery
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.wneu.2016.02.075
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Spinal tuberculosis is the most common form of tuberculosis affecting bone and often needs surgical treatment. Single anterior, single posterior, and combined anterior and posterior approaches are the 3 most commonly used approaches in surgical treatment. Clinically, the choice of optimal surgical approach r...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.12.023
更新日期：2020-12-11 00:00:00
abstract：BACKGROUND:Isolated hypoglossal nerve palsy caused by an atlantooccipital synovial cyst is a rare lesion, with fewer than 5 cases reported in the literature. CASE DESCRIPTION:Our patient presented with acute hypoglossal nerve dysfunction. Our differential included neoplasm, trauma, stroke, multiple sclerosis, or other...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.03.159
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:Intracranial aneurysms (IAs) are occasionally associated with moyamoya disease (MMD). The purpose of this study was to elucidate differences between patients with MMD with and without IAs and differences between patients with IAs at different locations. METHODS:Between May 2012 and December 2017, consecutive...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.10.118
更新日期：2020-10-27 00:00:00
abstract：:Control of bleeding in the confined area of the skull is imperative for successful neurosurgery and the prevention of devastating complications such as postoperative hemorrhage. This paper reviews the historical evolution of methods to achieve successful hemostasis in neurosurgery from the early1800s to today. The maj...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2018.12.015
更新日期：2018-12-19 00:00:00
abstract：BACKGROUND:Poor-grade aneurysmal subarachnoid hemorrhage (aSAH) is associated with increased intracranial pressure, and these patients are unstable with a high risk of rebleeding. Computed tomography angiography (CTA) has been proposed as an examination tool for the rapid detection of ruptured aneurysms. We aimed to de...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2016.03.099
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:VerifyNow-directed personalized antiplatelet therapy for aneurysm embolization with a Pipeline Embolization Device (PED) remains controversial. Evaluate thrombotic complications between patients who received VerifyNow-directed personalized antiplatelet therapy versus those who did not after PED flow diversio...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.03.046
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:De novo aneurysm formation has been reported as a rare complication of superficial temporal artery (STA) to middle cerebral artery (MCA) bypass surgery. CASE DESCRIPTION:The first patient with intracerebral hemorrhage had a ruptured de novo aneurysm arising from the recipient MCA at 6 years after undergoing...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2016.05.075
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Intracranial nail gun injury is a rare traumatic event and can result from a suicide attempt. Cerebral angiography is essential in the evaluation of damage to the intracranial vessels, and surgical removal of nails is generally the optimal treatment. Intraventricular hemorrhage can happen after removal of in...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.07.104
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:A spontaneous persistent primitive trigeminal artery-cavernous sinus fistula (PCF) is extremely rare. Until recently, endovascular treatment for PCF involving transarterial and/or transvenous coil embolization of the cavernous sinus (with/without the persistent trigeminal artery) was commonly performed. Howe...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.05.003
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:Evaluation of lumbar canal dimensions in a Chicago population born in 2 different decades. METHODS:This is a retrospective chart review analyzing computed tomography reconstruction from patients born between 1940 and 1949 (older group) and 1970 and 1979 (younger group). The cross-sectional area (CSA) and ant...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.11.039
更新日期：2020-11-16 00:00:00
abstract：OBJECTIVE:Percutaneous endoscopic lumbar discectomy is an effective way to treat lumbar disc herniation. Traditional preoperative planning based on a 2-dimensional method by magnetic resonance/computed tomography may cause inaccuracy of puncture during surgery. We used virtual reality to stimulate a surgery environment...
journal_title：World neurosurgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.wneu.2018.08.082
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Our objective was to analyze the relevance, potential prognostic factors, and complications of endoscopic third ventriculostomy (ETV) in patients with shunt failures. METHODS:Among 721 ETVs performed between 1999 and 2013, we studied 53 patients with shunts (31 men, 21 less than 18 years of age) who had an ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.01.058
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation within or adjacent to the subthalamic nucleus (STN) represents the most common stereotactic procedure performed for Parkinson disease. Better STN imaging is often regarded as a requirement for improving stereotactic targeting. However, it is unclear whether there is consensus about the...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.11.012
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:To describe epidemiology in relation to gender differences and treatment modalities 10 years after intracranial aneurysm rupture in the Stockholm cohort 1996-1999. METHODS:A total of 468 consecutive patients with aneurysmal subarachnoid hemorrhage were followed-up in a retrospective cohort design 10 years af...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2012.06.041
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:Malformations in the craniocervical junction (CCJ) are rare in the pediatric population but often need surgical treatment. We present a pediatric case series of patients treated with a 2-stage surgical approach with a halo vest and occipitocervical fusion and review complications and outcomes. METHODS:A retr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.11.079
更新日期：2020-11-20 00:00:00
abstract：OBJECTIVE:To deduce structural trends in neurosurgery in Germany by comparison of data derived from polls conducted by the Deutsche Gesellschaft für Neurochirurgie (DGNC) in 1997, 2003 and 2008. METHODS:The questionnaires of the different polls probed a comparable set of issues. The data from the responding sample wer...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章
doi：10.1016/j.wneu.2011.05.060
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:Giant sacral schwannomas are rare and difficult to treat. Unexpected neurologic deficits after surgery and tumor recurrence should be considered when surgery is performed. We attempt to remove the tumors via piecemeal total or subtotal excision, leaving parts of the capsule adjacent to nerves to preserve the ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.113
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:We explored the external ventricular drain (EVD) practices in Thailand. METHODS:We performed a survey-based study to describe EVD insertion, maintenance, quality improvement (QI) practices, and incidence of EVD infection. RESULTS:The study included 58 of 101 hospitals contacted (57.4% response rate), with ≥...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.144
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:Medical complications severely impair recovery of neurosurgical patients after craniotomy. The purpose of this study was to identify patients at risk of peri- and postoperative medical complications. Therefore, we present a large population of patients with different medical complications after elective crani...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.03.087
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Inflammatory demyelinating changes in the absence of malignant cells can sometimes be found on initial biopsies preceding the diagnosis of primary central nervous system lymphoma (PCNSL), resulting in the term "sentinel" lesion. Sentinel lesions have been reported sporadically in literature, resulting in man...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.09.064
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Bipolar coagulation has enhanced the capabilities and safety profile of contemporary neurosurgery and has become indispensable in the neurosurgical armamentarium. Nevertheless, significant heat transfer issues remain to be resolved before it can achieve the status of minimal risk. METHODS:The Codman irrigat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2014.10.007
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To examine the occurrence of traumatic intracranial hemorrhage (tICH) and outcome in patients with minor head injury and assess the probable risk factors. METHODS:Patients with minor head injury who visited our hospital from January 2015 to July 2017 were registered consecutively, and enrolled patients were ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.06.044
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Aortic pseudoaneurysms are a rare cause of chronic back pain, usually resulting from compression of the adjacent neurovasculature. It is uncommon for patients with pseudoaneurysms of the abdominal aorta to present in a delayed fashion after initial traumatic injury. CASE DESCRIPTION:We describe an unusual c...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2017.11.035
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:Obesity has become a worldwide epidemic, with very few long-term successful treatment options for refractory disease. Deep brain stimulation (DBS) of the bilateral lateral hypothalamus (LH) in refractory obesity has been performed safely. However, questions remain regarding the optimal settings and its effect...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.10.002
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Novel audiovisual feedback methods were developed to improve image guidance during skull base surgery by providing audiovisual warnings when the drill tip enters a protective perimeter set at a distance around anatomic structures ("distance control") and visualizing bone drilling ("virtual drilling"). OBJEC...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.09.142
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Strokelike migraine attack after radiation therapy is a recently described clinical entity characterized by transient hemispheric dysfunction manifesting as, but not limited to, visuospatial deficits, confusion, hemisensory deficits, hemiparesis, aphasia, seizures, and, most prominently, headache in patients...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2013.01.028
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Cavernous hemangiomas account for 5%-13% of central nervous system vascular lesions. They are usually found intra-axially but rarely involve extra-axial structures, most commonly the middle cranial fossa. A cavernous hemangioma manifesting as a clinoid meningioma is extremely rare. CASE DESCRIPTION:A 36-yea...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.02.029
更新日期：2017-04-01 00:00:00
