Surgically induced SMART syndrome: case report and review of the literature.

Abstract:

BACKGROUND:Strokelike migraine attack after radiation therapy is a recently described clinical entity characterized by transient hemispheric dysfunction manifesting as, but not limited to, visuospatial deficits, confusion, hemisensory deficits, hemiparesis, aphasia, seizures, and, most prominently, headache in patients with a history of remote external beam radiation therapy to the brain. The radiographic hallmark on magnetic resonance imaging is the presence of transient, diffuse, unilateral gadolinium enhancement of the cortex with white matter sparing, usually corresponding to the previous radiation field. CASE DESCRIPTION:We present a case of strokelike migraine attacks after radiation therapy syndrome diagnosed immediately following a craniotomy and temporal lobectomy for recurrent metastatic tumor resection after prior gamma knife radiosurgery and whole-brain radiation therapy. CONCLUSION:SMART syndrome should be considered in the differential diagnosis of postsurgical patients with remote history of cranial irradiation and significant, new transient neurologic deficits not explainable by any other mechanism. It is possible that manipulation of the trigeminal ganglion, or the dura of the Meckel cave, contributed to triggering the manifestations of this syndrome in our patient during the immediate postoperative period.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Maloney PR,Rabinstein AA,Daniels DJ,Link MJ

doi

10.1016/j.wneu.2013.01.028

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

240.e7-12

issue

1-2

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(13)00089-2

journal_volume

82

pub_type

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