Gaucher disease: fate of the splenic remnant after partial splenectomy--a case of rapid enlargement.

Abstract:

:In Gaucher disease, partial splenectomy has been suggested for alleviating the complications of splenomegaly as well as for avoiding the immunologic compromise and potential acceleration of bony and hepatic involvement that may follow total splenic resection. However, the fate of the splenic remnant has been reported rarely. A subtotal splenectomy (85%) was performed in a 19-month-old girl with rapidly progressing Gaucher disease and massive splenomegaly (12% of body weight). Within 3 months, the splenic remnant had increased four-fold in size. Previous reports indicated only three Gaucher patients had significant enlargement of the splenic remnant after partial splenectomy. These findings indicate that splenomegaly may recur rapidly in Gaucher disease following partial splenectomy.

journal_name

J Pediatr Surg

authors

Fleshner PR,Astion DJ,Ludman MD,Aufses AH Jr,Grabowski GA,Dolgin SE

doi

10.1016/s0022-3468(89)80520-2

subject

Has Abstract

pub_date

1989-06-01 00:00:00

pages

610-2

issue

6

eissn

0022-3468

issn

1531-5037

pii

S0022346889002423

journal_volume

24

pub_type

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