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Vitamin D and cardiovascular disease: From atherosclerosis to myocardial infarction and stroke.

Abstract：

:There continues to be interest in understanding the role of vitamin D in the pathogenesis, epidemiology and prevention of cardiovascular disease (CVD). In fact vitamin D deficiency has been associated to an increased risk of developing CVD given to the relationship between low vitamin D levels and obesity, diabetes mellitus, dyslipidaemia, endothelial dysfunction and hypertension. However, although vitamin D has been identified as a potentially important marker of CVD, the mechanisms through which vitamin D deficiency leads from endothelial dysfunction to myocardial infarction and stroke are not fully understood. Thus, the goal of this review is to provide an updated review of the literature on the basic science of how vitamin D may affect the cardiovascular system and in particular to analyze the role that vitamin D may have in the whole dynamic process from the initiation of endothelial dysfunction to the development of myocardial infarction and stroke.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Muscogiuri G,Annweiler C,Duval G,Karras S,Tirabassi G,Salvio G,Balercia G,Kimball S,Kotsa K,Mascitelli L,Bhattoa HP,Colao A

doi

10.1016/j.ijcard.2016.12.053

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

577-584

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(16)34541-7

journal_volume

230

pub_type

杂志文章,评审

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