Complications Associated With Bone Morphogenetic Protein in the Lumbar Spine.

Abstract:

:Complications associated with the use of recombinant human bone morphogenetic protein in the lumbar spine include retrograde ejaculation, ectopic bone formation, vertebral osteolysis and subsidence, postoperative radiculitis, and hematoma and seroma. These complications are controversial and remain widely debated. This article discusses the reported complications and possible implications for the practicing spine surgeon. Understanding the complications associated with the use of recombinant human bone morphogenetic protein and the associated controversies allows for informed decision making by both the patient and the surgeon. [Orthopedics. 2017; 40(2):e229-e237.].

journal_name

Orthopedics

journal_title

Orthopedics

authors

Kang DG,Hsu WK,Lehman RA Jr

doi

10.3928/01477447-20161213-06

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

e229-e237

issue

2

eissn

0147-7447

issn

1938-2367

journal_volume

40

pub_type

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