Validation of a point-of-care prothrombin time test after cardiopulmonary bypass in cardiac surgery.

Abstract:

:Point-of-care coagulation monitoring can be used for the guidance of haemostasis management. However, the influence of time on point-of-care prothrombin time testing following protamine administration after cardiopulmonary bypass has not been investigated. Bland-Altman and error grid analysis were used to analyse the level of agreement between prothrombin time measurements from point-of-care and laboratory tests before cardiopulmonary bypass, and then 3 min, 6 min and 10 min after protamine administration. Prothrombin times were expressed as International Normalised Ratios. While the point-of-care and laboratory prothrombin time measurements showed a high level of agreement before bypass, this agreement deteriorated following protamine administration to a mean (SD) bias of -0.22 (0.13) [limits of agreement 0.48-0.04]. Error grid analysis revealed that 35 (70%) of the paired values showed a clinically relevant discrepancy in international normalised ratio. At 3 min, 6 min and 10 min after cardiopulmonary bypass there is a clinical unacceptable discrepancy between the point-of-care and laboratory measurement of prothrombin time.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Meesters MI,Kuiper G,Vonk AB,Loer SA,Boer C

doi

10.1111/anae.13591

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

1163-8

issue

10

eissn

0003-2409

issn

1365-2044

journal_volume

71

pub_type

杂志文章
  • C-reactive protein in patients undergoing cardiac surgery.

    abstract::Among 25 patients undergoing cardiac surgery with the aid of cardiopulmonary bypass, 13 who recovered uneventfully all had normal (less than 2 mg/litre) levels of serum C-reactive protein pre-operatively. In contrast, 10 of the 12 patients who suffered from various postoperative complications, including two who died, ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1986.tb12696.x

    authors: Boralessa H,de Beer FC,Manchie A,Whitwam JG,Pepys MB

    更新日期:1986-01-01 00:00:00

  • Anaesthetic manpower in the future in the UK.

    abstract::The short-term objective of the DHSS of a 1:1 consultant: junior ratio by 1988 is compatible with current trends in consultant expansion and implies no reduction in registrars before then. The target of doubling the number of consultants in 15 years cannot be met in anaesthesia without a fairly sharp, and relatively s...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1982.tb01862.x

    authors: Vickers MD

    更新日期:1982-09-01 00:00:00

  • Addition of clonidine to a continuous patient-controlled epidural infusion of low-concentration levobupivacaine plus sufentanil in primiparous women during labour.

    abstract::We studied the potentiation of analgesia for labour by the addition of clonidine to epidural low-concentration levobupivacaine with sufentanil in a randomised, double-blinded study. We enrolled primiparous women who were in spontaneous labour. The study solutions, made of 100 ml levobupivacaine 0.0625% plus sufentanil...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2011.06785.x

    authors: Bazin M,Bonnin M,Storme B,Bolandard F,Vernis L,Lavergne B,Pereira B,Bazin JE,Dualé C

    更新日期:2011-09-01 00:00:00

  • Vecuronium and atracurium infusions during hypothermic cardiopulmonary bypass.

    abstract::Two similar groups of patients undergoing coronary artery bypass grafting received either atracurium or vecuronium infusions for neuromuscular blockade. Both groups demonstrated a marked reduction in neuromuscular blocking requirements during hypothermic bypass at 30 C. The ratio of the dose rates at 30 C to that at 3...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1986.tb12916.x

    authors: Denny NM,Kneeshaw JD

    更新日期:1986-09-01 00:00:00

  • Comparison of rocuronium and suxamethonium for use during rapid sequence induction of anaesthesia.

    abstract::This study was designed to compare the tracheal intubating conditions during a rapid sequence induction of anaesthesia using rocuronium 0.6 (n = 61) or 1.0 mg.kg-1 (n = 130) or suxamethonium 1.0 mg.kg-1 (n = 127) as the neuromuscular blocking drugs. Anaesthesia was induced with fentanyl 1-2 micrograms.kg-1 and thiopen...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.1998.00342.x

    authors: McCourt KC,Salmela L,Mirakhur RK,Carroll M,Mäkinen MT,Kansanaho M,Kerr C,Roest GJ,Olkkola KT

    更新日期:1998-09-01 00:00:00

  • Airtraq laryngoscope versus conventional Macintosh laryngoscope: a systematic review and meta-analysis.

    abstract::The Airtraq laryngoscope is a single-use laryngoscope designed to facilitate tracheal intubation in patients with either normal or difficult airways. The aim of this systematic review and meta-analysis was to compare the Airtraq with the conventional Macintosh laryngoscope. Data were retrieved from Medline, Embase, th...

    journal_title:Anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1365-2044.2011.06871.x

    authors: Lu Y,Jiang H,Zhu YS

    更新日期:2011-12-01 00:00:00

  • Use of the Airtraq laryngoscope in a model of difficult intubation by prehospital providers not previously trained in laryngoscopy.

    abstract::This study evaluated the ability of prehospital providers who had no previous training in intubation, to use an Airtraq laryngoscope to intubate a manikin model of a Cormack and Lehane grade III/IV view. Volunteers attending the Australian College of Ambulance Professionals conference, Adelaide, in November 2006 recei...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2007.05215.x

    authors: Woollard M,Mannion W,Lighton D,Johns I,O'meara P,Cotton C,Smyth M

    更新日期:2007-10-01 00:00:00

  • Pompe's disease and anaesthesia.

    abstract::A case report of a child with Pompe's disease (glycogen storage disease Cori type II), who underwent two general anaesthetics, is presented. The progressive infiltration of heart and skeletal muscle with glycogen results in a severe form of cardiomyopathy and respiratory muscle weakness. Consequently, there are signif...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1986.tb13007.x

    authors: McFarlane HJ,Soni N

    更新日期:1986-12-01 00:00:00

  • The cardiovascular response to insertion of the intubating laryngeal mask airway.

    abstract::Sixty-one patients received a standardised anaesthetic and were randomly assigned to three groups: tracheal intubation via direct laryngoscopy, tracheal intubation via an intubating laryngeal mask airway with immediate removal of the device, and tracheal intubation via an intubating laryngeal mask airway with delayed ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2002.02463.x

    authors: Choyce A,Avidan MS,Harvey A,Patel C,Timberlake C,Sarang K,Tilbrook L

    更新日期:2002-04-01 00:00:00

  • Peri-operative cardiac biomarker screening: a narrative review.

    abstract::Peri-operative risk estimation has traditionally focused on assessing the likelihood of postoperative morbidity and mortality using pre-operative functional assessment. Although this strategy is currently recommended by most major society guidelines, contemporary evidence suggests that cardiac biomarker measurement ha...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.14920

    authors: Ruzycki SM,Prystajecky M,Driedger MR,Kachra R

    更新日期:2020-01-01 00:00:00

  • Dantrolene sodium and dystrophia myotonica.

    abstract::A patient with dystrophia myotonica was given dantrolene sodium to try to provide muscle relaxation during a cholecystectomy. Dantrolene was used as it is accepted that the drug has a place in the control of spasticity and also causes muscle relaxation, whereas conventional muscle relaxants are unable to control myoto...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1984.tb07364.x

    authors: Phillips DC,Ellis FR,Exley KA,Ness MA

    更新日期:1984-06-01 00:00:00

  • Pulmonary shunts in the prone position.

    abstract::Pulmonary shunting (Qs/Qt with the FIO2 = 1) was determined in ten young healthy non-obese patients prior to anaesthesia, 30 min after induction in the supine position and 1 h later during surgery in the prone position. Respiration was spontaneous in awake patients and was controlled following the induction of anaesth...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1978.tb08387.x

    authors: Stone JG,Khambatta HJ

    更新日期:1978-06-01 00:00:00

  • Tracheal intubation following training with the GlideScope compared to direct laryngoscopy.

    abstract:SUMMARY:Tracheal intubation using direct laryngoscopy has a high failure rate when performed by untrained medical personnel. This study compares tracheal intubation following direct laryngoscopy by inexperienced medical students when initially trained by using either the GlideScope, a video assisted laryngoscope, or a ...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2010.06335.x

    authors: Ayoub CM,Kanazi GE,Al Alami A,Rameh C,El-Khatib MF

    更新日期:2010-07-01 00:00:00

  • Validation of a pre-anaesthetic screening questionnaire.

    abstract::We developed a screening questionnaire to be used by nurses to decide which patients should see an anaesthetist for further evaluation before the day of surgery. Our objective was to measure the accuracy of responses to the questionnaire. Agreement between questionnaire responses and the anaesthetist's assessment was ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2003.03335.x

    authors: Hilditch WG,Asbury AJ,Jack E,McGrane S

    更新日期:2003-09-01 00:00:00

  • Airway management guidance for the endemic phase of COVID-19.

    abstract::It is now apparent that severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19) will remain endemic for some time. Improved therapeutics and a vaccine may shorten this period, but both are far from certain. Plans must be put in place on the assumption that the virus and its...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.15253

    authors: Cook TM,McGuire B,Mushambi M,Misra U,Carey C,Lucas N,O'Sullivan E,Harrop-Griffiths W

    更新日期:2021-02-01 00:00:00

  • Blood ordering practices in obstetric units in the United Kingdom.

    abstract::A postal questionnaire on blood ordering practices and blood availability was sent to 89 randomly selected maternity units within the United Kingdom. The replies demonstrated a wide variation in crossmatching practices. Of those units that replied, 56% crossmatch for elective and 64% for emergency Caesarean section, 5...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1993.tb07483.x

    authors: Clark VA,Wardall GJ,McGrady EM

    更新日期:1993-11-01 00:00:00

  • Use of a low-power nerve stimulator during sciatic nerve block.

    abstract::The use of a low-power nerve stimulator to aid nerve location during the performance of sciatic nerve block was compared with a conventional anatomically based technique. The success rate, both in terms of the production of an effective block and the duration of postoperative analgesia, was significantly higher in the...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb03043.x

    authors: Smith BE,Allison A

    更新日期:1987-03-01 00:00:00

  • Electro-acupuncture and postoperative emesis.

    abstract::One hundred unpremedicated female patients of ASA grade 1 or 2 who underwent laparoscopy as outpatients were allocated randomly to one of four groups. All patients received general anaesthesia with fentanyl, thiopentone, halothane, nitrous oxide and oxygen; suxamethonium was given to facilitate tracheal intubation. In...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1990.tb14744.x

    authors: Ho RT,Jawan B,Fung ST,Cheung HK,Lee JH

    更新日期:1990-04-01 00:00:00

  • Exposure of nitrous oxide to X-rays. Production of nitric oxide and nitrogen dioxide.

    abstract::X-radiation has been shown to produce nitric oxide (NO) and nitrogen dioxide (NO2) in the presence of nitrous oxide (N2O). The purpose of the present study was to confirm how much NO and NO2 was produced when constant amounts of nitrous oxide were exposed to constant X-radiation. Twenty polyethylene bottles (capacity ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1980.tb05073.x

    authors: Yanagida H,Nakajima M

    更新日期:1980-12-01 00:00:00

  • A comparison of the clinical use of the Laryngeal Tube S and the ProSeal Laryngeal Mask Airway by first-month anaesthesia residents in anaesthetised patients.

    abstract::The Laryngeal Tube S and the LMA-ProSeal are supraglottic instruments with an improved airway seal and a drainage tube to protect against regurgitation and to facilitate passage of a gastric tube. We compared the feasibility of these two instruments in a randomised, controlled clinical trial. One hundred and sixty pat...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2007.05073.x

    authors: Klaver NS,Kuizenga K,Ballast A,Fidler V

    更新日期:2007-07-01 00:00:00

  • Anaphylactic reaction after atropine.

    abstract::A 38-year-old woman developed symptoms of anaphylactic shock after intravenous atropine and required adrenaline to maintain perfusion pressure. A strongly positive response was obtained on intradermal testing. The Prausnitz-Kuestner test was also positive, which indicated the presence of drug specific IgE antibodies. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1988.tb05661.x

    authors: Aguilera L,Martinez-Bourio R,Cid C,Arino JJ,Saez de Eguilaz JL,Arizaga A

    更新日期:1988-11-01 00:00:00

  • Legal and ethical implications of defining an optimum means of achieving unconsciousness in assisted dying.

    abstract::A decision by a society to sanction assisted dying in any form should logically go hand-in-hand with defining the acceptable method(s). Assisted dying is legal in several countries and we have reviewed the methods commonly used, contrasting these with an analysis of capital punishment in the USA. We expected that, sin...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.14532

    authors: Sinmyee S,Pandit VJ,Pascual JM,Dahan A,Heidegger T,Kreienbühl G,Lubarsky DA,Pandit JJ

    更新日期:2019-05-01 00:00:00

  • Serious complications with dextran-70 despite hapten prophylaxis. Is it best avoided prior to delivery?

    abstract::Dextran is used clinically for plasma volume expansion, improvement of blood flow and thromboprophylaxis, but has been associated with untoward side effects. Immunoprophylaxis with dextran I (hapten), before the infusion of dextran-70, has reduced the incidence of serious dextran-induced anaphylactoid reactions. We re...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1991.tb09916.x

    authors: Berg EM,Fasting S,Sellevold OF

    更新日期:1991-12-01 00:00:00

  • Facilitation of laryngeal mask airway insertion: effects of remifentanil administered before induction with target-controlled propofol infusion.

    abstract::Eighty-six adult day-case patients were recruited into a prospective, randomised study and allocated to one of two groups. Patients received either intravenous remifentanil 0.3 microg.kg(-1) or an equivalent volume of sodium chloride 0.9% followed by induction of anaesthesia with propofol target-controlled infusion un...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2001.02059-5.x

    authors: Grewal K,Samsoon G

    更新日期:2001-09-01 00:00:00

  • The absence of teratogenic effects of some analgesics used in anaesthesia. Additional evidence from a mouse model.

    abstract::The possibility exists that agents used in anaesthesia may have adverse teratogenic effects on staff, patients, and developing fetuses. It has been shown that a range of neurotropic drugs, when injected into pregnant mice on the 9th day of gestation, produce a characteristic group of central nervous system malformatio...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1992.tb02267.x

    authors: Martin LV,Jurand A

    更新日期:1992-06-01 00:00:00

  • An unusual cause of neonatal respiratory distress. RDS in a neonate with a neuro-enteric cyst.

    abstract::A 2.5 kg male infant developed respiratory distress in the neonatal period. A diagnosis of idiopathic hyaline membrane disease was made and he was treated accordingly. At 24 hours of age he required intubation, and the immediate and dramatic improvement in his condition suggested that the original diagnosis was incorr...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1981.tb08817.x

    authors: Cahill JF

    更新日期:1981-08-01 00:00:00

  • Spinal anaesthesia for outpatient surgery.

    abstract::In a prospective study of 51 young male outpatients given spinal anaesthesia through a 25-gauge needle, we found a 37.2% incidence of postdural puncture headache. In addition, 54.9% complained of backache after surgery. Occurrence of headache significantly prolonged the sick-leave from work. General anaesthesia would ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1985.tb10612.x

    authors: Flaatten H,Raeder J

    更新日期:1985-11-01 00:00:00

  • Post-operative convulsions due to penicillin applied to the spinal theca.

    abstract::Two cases are described and discussed in which penicillin powder applied to the theca at the end of laminectomy caused delayed convulsions. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1975.tb00796.x

    authors: Bordbar A,Beheshti M

    更新日期:1975-01-01 00:00:00

  • Anticipated difficult airway during obstetric general anaesthesia: narrative literature review and management recommendations.

    abstract::We reviewed the literature on management of general and regional anaesthesia in pregnant women with anticipated airway difficulty. We identified 138 publications comprising 158 cases; these either described equipment or techniques for the provision of general anaesthesia, or the management of women with regional analg...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.15007

    authors: Mushambi MC,Athanassoglou V,Kinsella SM

    更新日期:2020-07-01 00:00:00

  • The use of etomidate infusions during anaesthesia for cardiopulmonary bypass.

    abstract::The effects of cardiopulmonary bypass and hypothermia were studied on the plasma concentration and metabolism of a continuous infusion of etomidate in six patients. Continuous etomidate infusions (20 micrograms/kg/minute) with analgesic cover may be a suitable anaesthetic for cardiac surgery. This rate of infusion pro...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1983.tb15183.x

    authors: Oduro A,Tomlinson AA,Voice A,Davies GK

    更新日期:1983-07-01 00:00:00